sphingolipid biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). (Gene Ontology, GO_0030148)
External Link http://amigo.geneontology.org/amigo/term/GO_0030148
Similar Terms
Downloads & Tools

Genes

78 genes participating in the sphingolipid biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACER1 alkaline ceramidase 1
ACER2 alkaline ceramidase 2
ACER3 alkaline ceramidase 3
AGK acylglycerol kinase
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
CERS2 ceramide synthase 2
CERS3 ceramide synthase 3
CERS4 ceramide synthase 4
CERS5 ceramide synthase 5
CERS6 ceramide synthase 6
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CSNK1G2 casein kinase 1, gamma 2
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22
DEGS1 delta(4)-desaturase, sphingolipid 1
DEGS2 delta(4)-desaturase, sphingolipid 2
ELOVL1 ELOVL fatty acid elongase 1
ELOVL2 ELOVL fatty acid elongase 2
ELOVL3 ELOVL fatty acid elongase 3
ELOVL4 ELOVL fatty acid elongase 4
ELOVL5 ELOVL fatty acid elongase 5
ELOVL6 ELOVL fatty acid elongase 6
ELOVL7 ELOVL fatty acid elongase 7
FA2H fatty acid 2-hydroxylase
FAM57B family with sequence similarity 57, member B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
GBA glucosidase, beta, acid
GDF1 growth differentiation factor 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HACD2 3-hydroxyacyl-CoA dehydratase 2
HACD3 3-hydroxyacyl-CoA dehydratase 3
HACD4 3-hydroxyacyl-CoA dehydratase 4
KDSR 3-ketodihydrosphingosine reductase
LARGE like-glycosyltransferase
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OSBP oxysterol binding protein
PLPP2 phospholipid phosphatase 2
PLPP3 phospholipid phosphatase 3
PNPLA1 patatin-like phospholipase domain containing 1
PPAP2A phosphatidic acid phosphatase type 2A
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
SAMD8 sterile alpha motif domain containing 8
SGMS1 sphingomyelin synthase 1
SGMS2 sphingomyelin synthase 2
SGPL1 sphingosine-1-phosphate lyase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SGPP2 sphingosine-1-phosphate phosphatase 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPNS2 spinster homolog 2 (Drosophila)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SPTSSA serine palmitoyltransferase, small subunit A
SPTSSB serine palmitoyltransferase, small subunit B
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TM9SF2 transmembrane 9 superfamily member 2
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa