sphingomyelin metabolic process Gene Set
Dataset
GO Biological Process Annotations 2025
Category
structural or functional annotations
Type
biological process
Description
The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine. (Gene Ontology , GO_0006684 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0006684
Similar Terms
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Genes
13 genes participating in the sphingomyelin metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.
Symbol
Name
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
OSBP
oxysterol binding protein
SAMD8
sterile alpha motif domain containing 8
SGMS1
sphingomyelin synthase 1
SGMS2
sphingomyelin synthase 2
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SMPD4
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
