sphingosine metabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues. (Gene Ontology, GO_0006670)
External Link http://amigo.geneontology.org/amigo/term/GO:0006670
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Genes

21 genes participating in the sphingosine metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACER1 alkaline ceramidase 1
ACER2 alkaline ceramidase 2
ACER3 alkaline ceramidase 3
AGK acylglycerol kinase
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
GBA1 glucosylceramidase beta 1
NAAA N-acylethanolamine acid amidase
PLPP1 phospholipid phosphatase 1
PLPP2 phospholipid phosphatase 2
PLPP3 phospholipid phosphatase 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SGPP2 sphingosine-1-phosphate phosphatase 2
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SPTSSA serine palmitoyltransferase, small subunit A
SPTSSB serine palmitoyltransferase, small subunit B