spike Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description An elongated inflorescence similar to a raceme but having the flowers sessile on the main axis. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001278)
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Genes

732 proteins co-occuring with the tissue spike in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CDSN corneodesmosin 3.20319
ACE2 angiotensin I converting enzyme 2 2.16655
NDC1 NDC1 transmembrane nucleoporin 2.053
COX6CP4 cytochrome c oxidase subunit VIc pseudogene 4 2.03
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.89668
MGAM maltase-glucoamylase 1.86513
ARHGAP21 Rho GTPase activating protein 21 1.8087
ERVW-1 endogenous retrovirus group W, member 1 1.79549
MT-ATP8 ATP synthase F0 subunit 8 1.67506
PVALB parvalbumin 1.65507
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.62856
CCK cholecystokinin 1.59424
PACS2 phosphofurin acidic cluster sorting protein 2 1.58141
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.46402
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 1.39927
AGPS alkylglycerone phosphate synthase 1.37316
INS insulin 1.34814
PPAN peter pan homolog (Drosophila) 1.33184
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.33139
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.30838
FURIN furin (paired basic amino acid cleaving enzyme) 1.30748
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.30343
DNAH8 dynein, axonemal, heavy chain 8 1.30253
TRH thyrotropin-releasing hormone 1.30208
FAM20C family with sequence similarity 20, member C 1.29534
CA1 carbonic anhydrase I 1.29534
GRM1 glutamate receptor, metabotropic 1 1.29399
KNG1 kininogen 1 1.28951
GJD2 gap junction protein, delta 2, 36kDa 1.28367
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 1.27157
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.27023
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 1.2452
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 1.24119
SST somatostatin 1.23985
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.23717
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.23673
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.23539
NOTCH1 notch 1 1.23494
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 1.23093
ADORA1 adenosine A1 receptor 1.2238
CSN3 casein kappa 1.21312
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.21268
SCN1A sodium channel, voltage gated, type I alpha subunit 1.19711
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 1.19045
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 1.17669
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 1.17358
TAC1 tachykinin, precursor 1 1.15008
MED12 mediator complex subunit 12 1.1359
PPP1R17 protein phosphatase 1, regulatory subunit 17 1.12305
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.12128
CNR1 cannabinoid receptor 1 (brain) 1.11199
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.10977
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 1.10624
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 1.09916
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.09208
SH2D3C SH2 domain containing 3C 1.07883
CD79A CD79a molecule, immunoglobulin-associated alpha 1.07441
TARBP2 TAR (HIV-1) RNA binding protein 2 1.06559
MLN motilin 1.06162
SCN10A sodium channel, voltage gated, type X alpha subunit 1.06162
POMC proopiomelanocortin 1.05545
HCRT hypocretin (orexin) neuropeptide precursor 1.05501
NPS neuropeptide S 1.05457
ERF Ets2 repressor factor 1.05369
PITX1 paired-like homeodomain 1 1.03302
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.0282
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 1.02206
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.01768
GP2 glycoprotein 2 (zymogen granule membrane) 1.01375
GYPE glycophorin E (MNS blood group) 1.01243
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.01025
ELL elongation factor RNA polymerase II 1.00981
RPS14 ribosomal protein S14 1.00807
CALB1 calbindin 1, 28kDa 1.00632
NPY neuropeptide Y 1.00109
SCN3A sodium channel, voltage gated, type III alpha subunit 0.978049
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.97285
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.971984
ACHE acetylcholinesterase (Yt blood group) 0.970253
CHAT choline O-acetyltransferase 0.96809
CD4 CD4 molecule 0.953409
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.952547
CAV3 caveolin 3 0.948239
CRH corticotropin releasing hormone 0.944366
GRM5 glutamate receptor, metabotropic 5 0.943505
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 0.941355
HRASLS5 HRAS-like suppressor family, member 5 0.937059
RYR1 ryanodine receptor 1 (skeletal) 0.934054
ANPEP alanyl (membrane) aminopeptidase 0.917779
FOS FBJ murine osteosarcoma viral oncogene homolog 0.916923
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.916923
RPS3 ribosomal protein S3 0.9118
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.911373
PORCN porcupine homolog (Drosophila) 0.90924
TMPRSS2 transmembrane protease, serine 2 0.908387
CCKBR cholecystokinin B receptor 0.907535
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.907535
CXXC5 CXXC finger protein 5 0.904553
CIC capicua transcriptional repressor 0.904127
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.899871
PLCZ1 phospholipase C, zeta 1 0.896895
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.890525
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.888405
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.881204
CTSC cathepsin C 0.879089
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.873172
TH tyrosine hydroxylase 0.873172
ICT1 immature colon carcinoma transcript 1 0.859258
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.858837
ALB albumin 0.858837
F2 coagulation factor II (thrombin) 0.858416
CALB2 calbindin 2 0.853368
FBXO17 F-box protein 17 0.852527
BCR breakpoint cluster region 0.850845
CCKAR cholecystokinin A receptor 0.850425
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.846644
DRD2 dopamine receptor D2 0.844126
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.842447
PROS1 protein S (alpha) 0.834061
DPP6 dipeptidyl-peptidase 6 0.829872
HRC histidine rich calcium binding protein 0.822757
PDYN prodynorphin 0.821085
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.818994
CA4 carbonic anhydrase IV 0.816486
ADCY2 adenylate cyclase 2 (brain) 0.816486
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.816068
CTSL cathepsin L 0.813979
KARS lysyl-tRNA synthetase 0.811056
LGI2 leucine-rich repeat LGI family, member 2 0.793959
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.790212
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.786883
GCG glucagon 0.785635
PTK7 protein tyrosine kinase 7 (inactive) 0.780648
BDNF brain-derived neurotrophic factor 0.77774
PCNXL2 pecanex-like 2 (Drosophila) 0.771514
DPP4 dipeptidyl-peptidase 4 0.768197
LCOR ligand dependent nuclear receptor corepressor 0.766954
DERA deoxyribose-phosphate aldolase (putative) 0.766125
ELP4 elongator acetyltransferase complex subunit 4 0.750818
ZFYVE21 zinc finger, FYVE domain containing 21 0.747515
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.743801
MYB v-myb avian myeloblastosis viral oncogene homolog 0.742564
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.741327
NGF nerve growth factor (beta polypeptide) 0.740915
SH2D3A SH2 domain containing 3A 0.740915
BCHE butyrylcholinesterase 0.739678
SACS sacsin molecular chaperone 0.736794
CD3D CD3d molecule, delta (CD3-TCR complex) 0.735971
RICTOR RPTOR independent companion of MTOR, complex 2 0.725685
MUT methylmalonyl CoA mutase 0.721166
OPRM1 opioid receptor, mu 1 0.720755
FSCN1 fascin actin-bundling protein 1 0.717882
UBIAD1 UbiA prenyltransferase domain containing 1 0.7105
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.705993
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.699853
HBG1 hemoglobin, gamma A 0.696989
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 0.692493
LGI1 leucine-rich, glioma inactivated 1 0.688409
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.688
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.686776
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.681471
GRP gastrin-releasing peptide 0.672506
GDF5 growth differentiation factor 5 0.667622
PLAGL2 pleiomorphic adenoma gene-like 2 0.667622
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.667215
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.663962
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.663555
NTS neurotensin 0.659897
CHMP2A charged multivesicular body protein 2A 0.657054
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.656242
CDKL5 cyclin-dependent kinase-like 5 0.653807
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.653807
PRL prolactin 0.6461
PTH parathyroid hormone 0.645695
CORT cortistatin 0.63719
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 0.634358
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.631527
AVP arginine vasopressin 0.62991
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.628697
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 0.624658
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.622639
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.622235
IL31RA interleukin 31 receptor A 0.622235
SARS seryl-tRNA synthetase 0.620621
CALCA calcitonin-related polypeptide alpha 0.619814
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.61699
IRGC immunity-related GTPase family, cinema 0.609735
GAL galanin/GMAP prepropeptide 0.603697
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.600479
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.600077
ADA adenosine deaminase 0.592043
CHRM2 cholinergic receptor, muscarinic 2 0.578416
TADA3 transcriptional adaptor 3 0.576015
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.576015
L3MBTL3 l(3)mbt-like 3 (Drosophila) 0.573616
LYPD1 LY6/PLAUR domain containing 1 0.573217
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.571219
GRM2 glutamate receptor, metabotropic 2 0.571219
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.571219
RPIA ribose 5-phosphate isomerase A 0.571219
STRCP1 stereocilin pseudogene 1 0.570021
STRC stereocilin 0.570021
MRRF mitochondrial ribosome recycling factor 0.564833
SPAG7 sperm associated antigen 7 0.563238
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.560449
FSCN3 fascin actin-bundling protein 3, testicular 0.559254
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 0.555274
BACE1 beta-site APP-cleaving enzyme 1 0.554478
GNS glucosamine (N-acetyl)-6-sulfatase 0.552888
GP5 glycoprotein V (platelet) 0.550106
ATP13A4 ATPase type 13A4 0.549312
TSPO translocator protein (18kDa) 0.547724
FSCN2 fascin actin-bundling protein 2, retinal 0.546136
RPL5 ribosomal protein L5 0.543756
SNN stannin 0.543756
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.538209
DAND5 DAN domain family member 5, BMP antagonist 0.533856
COBL cordon-bleu WH2 repeat protein 0.533856
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.531879
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.529903
DCPS decapping enzyme, scavenger 0.529903
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 0.527928
ZNF32 zinc finger protein 32 0.523982
CLEC14A C-type lectin domain family 14, member A 0.521617
SENP6 SUMO1/sentrin specific peptidase 6 0.520829
TKFC triokinase/FMN cyclase 0.520435
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.520435
RPS11 ribosomal protein S11 0.519253
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 0.516891
CA3 carbonic anhydrase III 0.51571
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 0.515317
ASPA aspartoacylase 0.514924
GRIK1 glutamate receptor, ionotropic, kainate 1 0.51453
SPTBN4 spectrin, beta, non-erythrocytic 4 0.513743
MYBPC1 myosin binding protein C, slow type 0.513743
THYN1 thymocyte nuclear protein 1 0.511778
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.511778
HHAT hedgehog acyltransferase 0.510992
GAST gastrin 0.506672
DUSP26 dual specificity phosphatase 26 (putative) 0.502357
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.502357
SRPX2 sushi-repeat containing protein, X-linked 2 0.499223
CLIP1 CAP-GLY domain containing linker protein 1 0.499223
APP amyloid beta (A4) precursor protein 0.498832
TMPRSS11E transmembrane protease, serine 11E 0.498832
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.498048
NLE1 notchless homolog 1 (Drosophila) 0.496874
MSTO1 misato 1, mitochondrial distribution and morphology regulator 0.496483
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 0.496483
HTN3 histatin 3 0.496092
GIF gastric intrinsic factor (vitamin B synthesis) 0.494528
VIP vasoactive intestinal peptide 0.494528
MEA1 male-enhanced antigen 1 0.492572
SYP synaptophysin 0.489447
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.487106
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.487106
AGO4 argonaute RISC catalytic component 4 0.484766
MMD monocyte to macrophage differentiation-associated 0.483206
HRH3 histamine receptor H3 0.482428
ALLC allantoicase 0.477756
PTN pleiotrophin 0.476979
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.476979
RPA3 replication protein A3, 14kDa 0.476589
SIGLEC10 sialic acid binding Ig-like lectin 10 0.476201
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.470375
STX8 syntaxin 8 0.468436
PER1 period circadian clock 1 0.466111
FN1 fibronectin 1 0.464174
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.461465
MATK megakaryocyte-associated tyrosine kinase 0.458759
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 0.457214
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.456828
FES FES proto-oncogene, tyrosine kinase 0.456442
CAT catalase 0.455284
CAPNS1 calpain, small subunit 1 0.452969
ATL3 atlastin GTPase 3 0.451428
TRDN triadin 0.451428
CELF4 CUGBP, Elav-like family member 4 0.450657
MECP2 methyl CpG binding protein 2 0.449501
TACR1 tachykinin receptor 1 0.446807
GYPA glycophorin A (MNS blood group) 0.446038
C5ORF38 chromosome 5 open reading frame 38 0.445653
CD209 CD209 molecule 0.445268
NBPF10 neuroblastoma breakpoint family, member 10 0.442578
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.442194
AXIN2 axin 2 0.442194
COX5A cytochrome c oxidase subunit Va 0.441426
CTSS cathepsin S 0.440658
GYG2 glycogenin 2 0.440658
CAV2 caveolin 2 0.438356
HOMER1 homer scaffolding protein 1 0.436822
CA2 carbonic anhydrase II 0.436822
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.436822
ISCA2 iron-sulfur cluster assembly 2 0.436438
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 0.436438
PGLYRP3 peptidoglycan recognition protein 3 0.436055
SV2A synaptic vesicle glycoprotein 2A 0.435289
THUMPD2 THUMP domain containing 2 0.427254
MYRF myelin regulatory factor 0.425726
PRDM4 PR domain containing 4 0.425726
GPHN gephyrin 0.425344
ENGASE endo-beta-N-acetylglucosaminidase 0.424581
MYLK myosin light chain kinase 0.421529
TOB1 transducer of ERBB2, 1 0.420766
PNPO pyridoxamine 5'-phosphate oxidase 0.420385
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.419623
PRRT2 proline-rich transmembrane protein 2 0.419242
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.415434
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.413912
GHRH growth hormone releasing hormone 0.413151
MTO1 mitochondrial tRNA translation optimization 1 0.411631
FOXD3 forkhead box D3 0.410491
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.410491
RCOR2 REST corepressor 2 0.410111
DEFB1 defensin, beta 1 0.407832
USF2 upstream transcription factor 2, c-fos interacting 0.406315
SCN7A sodium channel, voltage gated, type VII alpha subunit 0.405935
SDF4 stromal cell derived factor 4 0.405935
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.405555
KISS1R KISS1 receptor 0.404039
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.40366
MED28 mediator complex subunit 28 0.402523
MYH15 myosin, heavy chain 15 0.402144
STIM1 stromal interaction molecule 1 0.401007
SEPT3 septin 3 0.400628
CD151 CD151 molecule (Raph blood group) 0.40025
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.399492
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 0.399114
SELM selenoprotein M 0.397222
OPN4 opsin 4 0.395331
ATN1 atrophin 1 0.395331
S100A13 S100 calcium binding protein A13 0.393819
UQCRB ubiquinol-cytochrome c reductase binding protein 0.392686
INTS8 integrator complex subunit 8 0.392686
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 0.391176
A1BG alpha-1-B glycoprotein 0.390799
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.390799
MN1 meningioma (disrupted in balanced translocation) 1 0.389666
TBATA thymus, brain and testes associated 0.389666
SKAP2 src kinase associated phosphoprotein 2 0.388535
IGHV3-30 immunoglobulin heavy variable 3-30 0.388535
NARF nuclear prelamin A recognition factor 0.387781
JMJD6 jumonji domain containing 6 0.38552
KCNK18 potassium channel, two pore domain subfamily K, member 18 0.384766
L3MBTL1 l(3)mbt-like 1 (Drosophila) 0.384013
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.383637
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.382508
SALL4 spalt-like transcription factor 4 0.382508
NUTF2 nuclear transport factor 2 0.381379
GPR162 G protein-coupled receptor 162 0.381379
NGLY1 N-glycanase 1 0.379875
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.379123
IL6 interleukin 6 0.374243
CLEC4M C-type lectin domain family 4, member M 0.373868
UBE3A ubiquitin protein ligase E3A 0.371994
TPCN1 two pore segment channel 1 0.370121
PNOC prepronociceptin 0.368624
HDX highly divergent homeobox 0.36825
GUCY2C guanylate cyclase 2C 0.367502
ARX aristaless related homeobox 0.365633
NPR1 natriuretic peptide receptor 1 0.365633
PNMT phenylethanolamine N-methyltransferase 0.36526
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 0.364513
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.363766
MON1A MON1 secretory trafficking family member A 0.363393
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.362646
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.362646
FOXM1 forkhead box M1 0.361155
FUT2 fucosyltransferase 2 (secretor status included) 0.361155
PSENEN presenilin enhancer gamma secretase subunit 0.359664
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.359292
EFS embryonal Fyn-associated substrate 0.358919
TMPRSS11D transmembrane protease, serine 11D 0.354826
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 0.354826
CCDC112 coiled-coil domain containing 112 0.35334
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.35334
MKRN3 makorin ring finger protein 3 0.352598
SOD2 superoxide dismutase 2, mitochondrial 0.350001
MMRN2 multimerin 2 0.348889
CRHR1 corticotropin releasing hormone receptor 1 0.348148
DBT dihydrolipoamide branched chain transacylase E2 0.344449
PRB3 proline-rich protein BstNI subfamily 3 0.34334
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 0.341863
XYLB xylulokinase homolog (H. influenzae) 0.341863
APEH acylaminoacyl-peptide hydrolase 0.341495
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.340757
LATS1 large tumor suppressor kinase 1 0.340388
GRID2 glutamate receptor, ionotropic, delta 2 0.340019
SOS1 son of sevenless homolog 1 (Drosophila) 0.33744
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.337072
SDC2 syndecan 2 0.336704
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.336336
EDN1 endothelin 1 0.3356
GHRL ghrelin/obestatin prepropeptide 0.335233
HRH1 histamine receptor H1 0.33413
PFKM phosphofructokinase, muscle 0.333028
OCA2 oculocutaneous albinism II 0.333028
PON1 paraoxonase 1 0.332661
TMEM11 transmembrane protein 11 0.330827
SP6 Sp6 transcription factor 0.330827
SEMG1 semenogelin I 0.329361
CTRL chymotrypsin-like 0.329361
CCDC130 coiled-coil domain containing 130 0.328994
DSE dermatan sulfate epimerase 0.327896
TPH1 tryptophan hydroxylase 1 0.327896
PHF19 PHD finger protein 19 0.326432
NEK7 NIMA-related kinase 7 0.326067
DCX doublecortin 0.326067
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.326067
QDPR quinoid dihydropteridine reductase 0.325701
WNT10A wingless-type MMTV integration site family, member 10A 0.32497
OR13H1 olfactory receptor, family 13, subfamily H, member 1 0.324239
PLEK pleckstrin 0.323874
GALR1 galanin receptor 1 0.323874
VCL vinculin 0.323509
DOC2B double C2-like domains, beta 0.32205
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 0.321685
PCGF1 polycomb group ring finger 1 0.320591
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.319498
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.31877
RPS5 ribosomal protein S5 0.31877
PEX19 peroxisomal biogenesis factor 19 0.316588
TNF tumor necrosis factor 0.316224
TSPAN7 tetraspanin 7 0.315498
PLA2G1B phospholipase A2, group IB (pancreas) 0.315135
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.312957
MYLK3 myosin light chain kinase 3 0.312957
BTNL2 butyrophilin-like 2 0.312232
TMEM43 transmembrane protein 43 0.31187
MAP2 microtubule-associated protein 2 0.31187
SPTA1 spectrin, alpha, erythrocytic 1 0.31187
EDNRA endothelin receptor type A 0.311145
PHF12 PHD finger protein 12 0.309697
GPR176 G protein-coupled receptor 176 0.309335
GJA1 gap junction protein, alpha 1, 43kDa 0.308974
TRAK1 trafficking protein, kinesin binding 1 0.308974
MNX1 motor neuron and pancreas homeobox 1 0.308251
MAPT microtubule-associated protein tau 0.307167
AHSG alpha-2-HS-glycoprotein 0.307167
PDE5A phosphodiesterase 5A, cGMP-specific 0.30464
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.303919
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.303559
GSTM1 glutathione S-transferase mu 1 0.302838
AMY2A amylase, alpha 2A (pancreatic) 0.301758
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.300679
ERBB2 erb-b2 receptor tyrosine kinase 2 0.30032
LAX1 lymphocyte transmembrane adaptor 1 0.298883
CREB1 cAMP responsive element binding protein 1 0.296372
PPY pancreatic polypeptide 0.296372
RHO rhodopsin 0.295297
FBXO43 F-box protein 43 0.294581
SCN1B sodium channel, voltage gated, type I beta subunit 0.293151
ACP1 acid phosphatase 1, soluble 0.292436
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.292008
RPGRIP1L RPGRIP1-like 0.291365
OTOP1 otopetrin 1 0.290295
CYLD cylindromatosis (turban tumor syndrome) 0.289939
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.289226
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.289226
OTOF otoferlin 0.286736
LRP5 low density lipoprotein receptor-related protein 5 0.286736
CABP1 calcium binding protein 1 0.285884
FKBP1C FK506 binding protein 1C 0.285316
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.284891
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.283899
GH1 growth hormone 1 0.283899
PINK1 PTEN induced putative kinase 1 0.282483
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.28213
GLB1 galactosidase, beta 1 0.280717
LHB luteinizing hormone beta polypeptide 0.280364
MARK3 MAP/microtubule affinity-regulating kinase 3 0.280012
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 0.280012
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.279659
CRP C-reactive protein, pentraxin-related 0.278955
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.278251
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.277549
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.275794
ALPP alkaline phosphatase, placental 0.274394
PCDH19 protocadherin 19 0.2723
C8A complement component 8, alpha polypeptide 0.271952
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.271952
ERV3-1 endogenous retrovirus group 3, member 1 0.271604
PPT1 palmitoyl-protein thioesterase 1 0.271256
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.270214
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.269521
SLC10A4 solute carrier family 10, member 4 0.269521
CD44 CD44 molecule (Indian blood group) 0.268482
MREG melanoregulin 0.268482
RIMS2 regulating synaptic membrane exocytosis 2 0.268137
ADK adenosine kinase 0.267791
GP9 glycoprotein IX (platelet) 0.266413
IRF6 interferon regulatory factor 6 0.265725
PCSK7 proprotein convertase subtilisin/kexin type 7 0.265381
KRT77 keratin 77, type II 0.264353
ZDHHC17 zinc finger, DHHC-type containing 17 0.264011
QTRT1 queuine tRNA-ribosyltransferase 1 0.262645
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.261624
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.259254
KLK15 kallikrein-related peptidase 15 0.259254
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.258243
RPS10 ribosomal protein S10 0.258243
RIN2 Ras and Rab interactor 2 0.2559
LMNB1 lamin B1 0.2559
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.255234
CNOT2 CCR4-NOT transcription complex, subunit 2 0.255234
GRM8 glutamate receptor, metabotropic 8 0.253578
RASAL1 RAS protein activator like 1 (GAP1 like) 0.252919
SCN2A sodium channel, voltage gated, type II alpha subunit 0.251934
MDH1 malate dehydrogenase 1, NAD (soluble) 0.251606
F11R F11 receptor 0.251606
ALPPL2 alkaline phosphatase, placental-like 2 0.251606
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.250953
ALPL alkaline phosphatase, liver/bone/kidney 0.250953
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.250953
F9 coagulation factor IX 0.249977
RHOT1 ras homolog family member T1 0.249653
TLX3 T-cell leukemia homeobox 3 0.249329
CDKN2A cyclin-dependent kinase inhibitor 2A 0.249006
PER2 period circadian clock 2 0.248361
CSTB cystatin B (stefin B) 0.248361
RGS2 regulator of G-protein signaling 2 0.248361
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.24804
PEX5 peroxisomal biogenesis factor 5 0.24804
BSN bassoon presynaptic cytomatrix protein 0.24804
DEFB106B defensin, beta 106B 0.24676
ADGRL1 adhesion G protein-coupled receptor L1 0.246442
FMR1 fragile X mental retardation 1 0.245491
RNASEH2A ribonuclease H2, subunit A 0.245491
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.244545
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.244545
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 0.243918
GPER1 G protein-coupled estrogen receptor 1 0.243605
VIM vimentin 0.243294
GRM4 glutamate receptor, metabotropic 4 0.243294
CDH9 cadherin 9, type 2 (T1-cadherin) 0.242983
KDR kinase insert domain receptor 0.242672
GJB3 gap junction protein, beta 3, 31kDa 0.242363
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.241746
PHGDH phosphoglycerate dehydrogenase 0.241438
CANX calnexin 0.241438
STXBP5 syntaxin binding protein 5 (tomosyn) 0.240826
KLK3 kallikrein-related peptidase 3 0.240216
SYT1 synaptotagmin I 0.239913
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.238406
OSTF1 osteoclast stimulating factor 1 0.238108
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.23781
GLUL glutamate-ammonia ligase 0.237216
AURKA aurora kinase A 0.236921
PANX1 pannexin 1 0.236627
NEK4 NIMA-related kinase 4 0.23604
SBF1 SET binding factor 1 0.235167
ELP3 elongator acetyltransferase complex subunit 3 0.234878
HN1 hematological and neurological expressed 1 0.234302
PDLIM4 PDZ and LIM domain 4 0.234302
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.234016
DACT2 dishevelled-binding antagonist of beta-catenin 2 0.233446
NID1 nidogen 1 0.233162
F2R coagulation factor II (thrombin) receptor 0.232599
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.232039
FGL2 fibrinogen-like 2 0.231206
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 0.231206
EIF3F eukaryotic translation initiation factor 3, subunit F 0.229032
GFAP glial fibrillary acidic protein 0.228234
TEF thyrotrophic embryonic factor 0.227707
HOXA13 homeobox A13 0.227445
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.227186
IFITM5 interferon induced transmembrane protein 5 0.226411
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.226155
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.2259
SCX scleraxis basic helix-loop-helix transcription factor 0.2259
PRODH proline dehydrogenase (oxidase) 1 0.224398
KRT75 keratin 75, type II 0.223906
PRAMEF6 PRAME family member 6 0.223419
LST1 leukocyte specific transcript 1 0.222699
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.222699
GLI1 GLI family zinc finger 1 0.222699
DAZAP1 DAZ associated protein 1 0.219928
ADARB1 adenosine deaminase, RNA-specific, B1 0.219485
NR1D1 nuclear receptor subfamily 1, group D, member 1 0.219264
GAP43 growth associated protein 43 0.21883
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.218398
ELF2 E74-like factor 2 (ets domain transcription factor) 0.217346
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.217139
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.21573
CAV1 caveolin 1, caveolae protein, 22kDa 0.215534
CCNF cyclin F 0.215341
CABIN1 calcineurin binding protein 1 0.215341
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.214954
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.214954
MEMO1 mediator of cell motility 1 0.213833
APCS amyloid P component, serum 0.21365
APOLD1 apolipoprotein L domain containing 1 0.213112
CALR calreticulin 0.212761
ADAM17 ADAM metallopeptidase domain 17 0.212586
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.20834
GLUD1 glutamate dehydrogenase 1 0.206334
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.204668
PDX1 pancreatic and duodenal homeobox 1 0.20135
PDE4D phosphodiesterase 4D, cAMP-specific 0.199549
SCP2 sterol carrier protein 2 0.198478
GUSB glucuronidase, beta 0.19717
PRTN3 proteinase 3 0.196136
FLAD1 flavin adenine dinucleotide synthetase 1 0.195793
FBN1 fibrillin 1 0.194228
PGD phosphogluconate dehydrogenase 0.194222
PPA1 pyrophosphatase (inorganic) 1 0.194048
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.19399
TGM2 transglutaminase 2 0.193957
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.1938
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.193778
SOS2 son of sevenless homolog 2 (Drosophila) 0.193344
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.193044
NAGK N-acetylglucosamine kinase 0.192591
SSPN sarcospan 0.192343
PEX6 peroxisomal biogenesis factor 6 0.192122
PAOX polyamine oxidase (exo-N4-amino) 0.191629
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.191546
CUL2 cullin 2 0.19149
TPM3 tropomyosin 3 0.191448
SPEN spen family transcriptional repressor 0.191155
RBM15 RNA binding motif protein 15 0.190809
PTDSS1 phosphatidylserine synthase 1 0.189878
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.189763
IREB2 iron-responsive element binding protein 2 0.189763
WIPF3 WAS/WASL interacting protein family, member 3 0.189705
CKAP5 cytoskeleton associated protein 5 0.189299
COPS2 COP9 signalosome subunit 2 0.189046
KDM5B lysine (K)-specific demethylase 5B 0.189046
CLEC4D C-type lectin domain family 4, member D 0.189037
SRM spermidine synthase 0.189028
CHURC1 churchill domain containing 1 0.188931
EMP2 epithelial membrane protein 2 0.188669
EMC3 ER membrane protein complex subunit 3 0.188327
HIF3A hypoxia inducible factor 3, alpha subunit 0.187944
MANBA mannosidase, beta A, lysosomal 0.187497
LAMB1 laminin, beta 1 0.187221
TSN translin 0.187106
SPEG SPEG complex locus 0.187075
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.186819
ZDHHC23 zinc finger, DHHC-type containing 23 0.186787
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.18669
KLHL2 kelch-like family member 2 0.186613
RAP1B RAP1B, member of RAS oncogene family 0.186493
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.186448
HYLS1 hydrolethalus syndrome 1 0.186269
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.186247
TUB tubby bipartite transcription factor 0.186156
DICER1 dicer 1, ribonuclease type III 0.185597
CCNT1 cyclin T1 0.185465
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.185331
NPB neuropeptide B 0.185184
MATN3 matrilin 3 0.185034
SRL sarcalumenin 0.184858
NRG2 neuregulin 2 0.184391
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.184325
HOXD13 homeobox D13 0.184272
KLHL17 kelch-like family member 17 0.184272
COPA coatomer protein complex, subunit alpha 0.18411
RORB RAR-related orphan receptor B 0.184069
EMILIN1 elastin microfibril interfacer 1 0.183809
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 0.183726
RAP1A RAP1A, member of RAS oncogene family 0.183515
PLAUR plasminogen activator, urokinase receptor 0.183501
DHPS deoxyhypusine synthase 0.183067
ASPN asporin 0.182649
GYS1 glycogen synthase 1 (muscle) 0.182603
CARD16 caspase recruitment domain family, member 16 0.18209
CD177 CD177 molecule 0.182026
AACS acetoacetyl-CoA synthetase 0.181752
ANGPTL6 angiopoietin-like 6 0.181605
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 0.181571
WEE1 WEE1 G2 checkpoint kinase 0.180753
MACF1 microtubule-actin crosslinking factor 1 0.180593
SCAI suppressor of cancer cell invasion 0.179729
FICD FIC domain containing 0.179343
CAPN1 calpain 1, (mu/I) large subunit 0.179284
ALDOC aldolase C, fructose-bisphosphate 0.178724
ALDOB aldolase B, fructose-bisphosphate 0.178182
G6PD glucose-6-phosphate dehydrogenase 0.17733
EEF1A1P6 eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 0.177056
MASP2 mannan-binding lectin serine peptidase 2 0.176965
IPP intracisternal A particle-promoted polypeptide 0.176965
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.176496
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.176207
CNTN5 contactin 5 0.175962
MPG N-methylpurine-DNA glycosylase 0.175938
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.175863
UBE2H ubiquitin-conjugating enzyme E2H 0.175639
OCM2 oncomodulin 2 0.175307
NELFCD negative elongation factor complex member C/D 0.175153
OCM oncomodulin 0.175047
CKAP2 cytoskeleton associated protein 2 0.174889
SAA1 serum amyloid A1 0.174863
ALDOA aldolase A, fructose-bisphosphate 0.174352
BCO1 beta-carotene oxygenase 1 0.17416
BHMT betaine--homocysteine S-methyltransferase 0.173568
LGMN legumain 0.173568
AMD1 adenosylmethionine decarboxylase 1 0.173453
DCC DCC netrin 1 receptor 0.17331
ARAF A-Raf proto-oncogene, serine/threonine kinase 0.173133
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.172956
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.172135
DUSP1 dual specificity phosphatase 1 0.172041
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.172041
FYB FYN binding protein 0.172009
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 0.171852
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.171338
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.171111
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.170301
GYPC glycophorin C (Gerbich blood group) 0.169814
BEST1 bestrophin 1 0.169672
MAT1A methionine adenosyltransferase I, alpha 0.169636
ASPH aspartate beta-hydroxylase 0.168874
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.168727
LAP3 leucine aminopeptidase 3 0.168615
RAG1 recombination activating gene 1 0.168387
FABP3 fatty acid binding protein 3, muscle and heart 0.168236
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.167969
AK1 adenylate kinase 1 0.167733
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.16722
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.165903
CBS cystathionine-beta-synthase 0.165687
GSR glutathione reductase 0.165342
SUMF2 sulfatase modifying factor 2 0.162729
TCN2 transcobalamin II 0.162435
AK6 adenylate kinase 6 0.161945
PRF1 perforin 1 (pore forming protein) 0.161794
CSN1S1 casein alpha s1 0.16093
PRSS21 protease, serine, 21 (testisin) 0.160459
RPS19 ribosomal protein S19 0.159007
PTMS parathymosin 0.157133
GPR182 G protein-coupled receptor 182 0.155634