spine Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck. (Gene Ontology, GO_0044309)
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Genes

110 genes co-occuring with the biological term spine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ADAM10 ADAM metallopeptidase domain 10
ADIPOQ adiponectin, C1Q and collagen domain containing
AHSG alpha-2-HS-glycoprotein
ALOX12 arachidonate 12-lipoxygenase
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARF6 ADP-ribosylation factor 6
ARHGAP32 Rho GTPase activating protein 32
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ASCL4 achaete-scute family bHLH transcription factor 4
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAIAP2 BAI1-associated protein 2
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
CDK5 cyclin-dependent kinase 5
CDKL5 cyclin-dependent kinase-like 5
CHMP2B charged multivesicular body protein 2B
CLCN7 chloride channel, voltage-sensitive 7
CLEC2D C-type lectin domain family 2, member D
COL1A1 collagen, type I, alpha 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DBN1 drebrin 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLG4 discs, large homolog 4 (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
DSTN destrin (actin depolymerizing factor)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
FGF23 fibroblast growth factor 23
FLNB filamin B, beta
FMN2 formin 2
FMR1 fragile X mental retardation 1
FNBP1 formin binding protein 1
FRMPD4 FERM and PDZ domain containing 4
GLUD1 glutamate dehydrogenase 1
GPRC6A G protein-coupled receptor, class C, group 6, member A
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HMGN3 high mobility group nucleosomal binding domain 3
HOXD4 homeobox D4
IAPP islet amyloid polypeptide
ICAM5 intercellular adhesion molecule 5, telencephalin
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
INS insulin
ITSN2 intersectin 2
KALRN kalirin, RhoGEF kinase
KL klotho
LAMA2 laminin, alpha 2
LMNA lamin A/C
LRP5 low density lipoprotein receptor-related protein 5
LTF lactotransferrin
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MECP2 methyl CpG binding protein 2
MEF2C myocyte enhancer factor 2C
MIR221 microRNA 221
MIRLET7I microRNA let-7i
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NF1 neurofibromin 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NPPB natriuretic peptide B
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUMB numb homolog (Drosophila)
OPHN1 oligophrenin 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PPARG peroxisome proliferator-activated receptor gamma
PSEN1 presenilin 1
PTH parathyroid hormone
PYY peptide YY
QPCT glutaminyl-peptide cyclotransferase
RAB8A RAB8A, member RAS oncogene family
RANBP2 RAN binding protein 2
RCAN1 regulator of calcineurin 1
RET ret proto-oncogene
RTN4 reticulon 4
SEPN1 selenoprotein N, 1
SFRP4 secreted frizzled-related protein 4
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SOST sclerostin
SPTBN1 spectrin, beta, non-erythrocytic 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SSH1 slingshot protein phosphatase 1
STK24 serine/threonine kinase 24
SYNPO synaptopodin
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
VASP vasodilator-stimulated phosphoprotein
VCP valosin containing protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WASF1 WAS protein family, member 1