| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the spiperone-5777 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AGR2 | anterior gradient 2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BMP2 | bone morphogenetic protein 2 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CBS | cystathionine-beta-synthase |
| CCNA1 | cyclin A1 |
| CD300C | CD300c molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN1 | claudin 1 |
| CPB2 | carboxypeptidase B2 (plasma) |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FAM129A | family with sequence similarity 129, member A |
| FICD | FIC domain containing |
| FNDC3B | fibronectin type III domain containing 3B |
| FST | follistatin |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HPCAL4 | hippocalcin like 4 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HYOU1 | hypoxia up-regulated 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| INHBA | inhibin, beta A |
| INSIG1 | insulin induced gene 1 |
| JUNB | jun B proto-oncogene |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KRT16 | keratin 16, type I |
| KRT17 | keratin 17, type I |
| KRT34 | keratin 34, type I |
| LAMB3 | laminin, beta 3 |
| LIF | leukemia inhibitory factor |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MED25 | mediator complex subunit 25 |
| MIR22HG | MIR22 host gene |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| PTX3 | pentraxin 3, long |
| PVR | poliovirus receptor |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| S100P | S100 calcium binding protein P |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STC2 | stanniocalcin 2 |
| SYT1 | synaptotagmin I |
| TGFB2 | transforming growth factor, beta 2 |
| THBD | thrombomodulin |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TMEM50B | transmembrane protein 50B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIB3 | tribbles pseudokinase 3 |
| TSPYL2 | TSPY-like 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF804A | zinc finger protein 804A |
| Symbol | Name |
|---|---|
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADCY6 | adenylate cyclase 6 |
| ADRB2 | adrenoceptor beta 2, surface |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| B3GNT1 | |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CASKIN2 | CASK interacting protein 2 |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CBR3 | carbonyl reductase 3 |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC7 | cell division cycle 7 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFAP44 | cilia and flagella associated protein 44 |
| CLSPN | claspin |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DIXDC1 | DIX domain containing 1 |
| DNA2 | DNA replication helicase/nuclease 2 |
| E2F8 | E2F transcription factor 8 |
| EFNA3 | ephrin-A3 |
| EN1 | engrailed homeobox 1 |
| EPHB6 | EPH receptor B6 |
| EPN3 | epsin 3 |
| FAM111A | family with sequence similarity 111, member A |
| FHOD1 | formin homology 2 domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FZD8 | frizzled class receptor 8 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR3 | G protein-coupled receptor 3 |
| GRPR | gastrin-releasing peptide receptor |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H3G | histone cluster 1, H3g |
| HOXA2 | homeobox A2 |
| HOXB13 | homeobox B13 |
| HOXC10 | homeobox C10 |
| ICK | intestinal cell (MAK-like) kinase |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL4R | interleukin 4 receptor |
| IPO8 | importin 8 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITGA10 | integrin, alpha 10 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIF20A | kinesin family member 20A |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICALL2 | MICAL-like 2 |
| MKI67 | marker of proliferation Ki-67 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NOL12 | nucleolar protein 12 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PALMD | palmdelphin |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE12 | phosphodiesterase 12 |
| PMCH | pro-melanin-concentrating hormone |
| PRAME | preferentially expressed antigen in melanoma |
| PROS1 | protein S (alpha) |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SALL2 | spalt-like transcription factor 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SUOX | sulfite oxidase |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TCTN1 | tectonic family member 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TOM1 | target of myb1 (chicken) |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TREX1 | three prime repair exonuclease 1 |
| TSPAN15 | tetraspanin 15 |
| UNC119 | unc-119 homolog (C. elegans) |
| VASH2 | vasohibin 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF107 | zinc finger protein 107 |
| ZNF358 | zinc finger protein 358 |
| ZNF862 | zinc finger protein 862 |
