| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the spiradoline-3901 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADM | adrenomedullin |
| ADRA2B | adrenoceptor alpha 2B |
| AHNAK | AHNAK nucleoprotein |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARL3 | ADP-ribosylation factor-like 3 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BDNF | brain-derived neurotrophic factor |
| C18ORF25 | chromosome 18 open reading frame 25 |
| C3AR1 | complement component 3a receptor 1 |
| CABP2 | calcium binding protein 2 |
| CAMK1G | calcium/calmodulin-dependent protein kinase IG |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CDC25C | cell division cycle 25C |
| CEP152 | centrosomal protein 152kDa |
| CLSTN2 | calsyntenin 2 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DRD2 | dopamine receptor D2 |
| EFNA5 | ephrin-A5 |
| FAM63B | family with sequence similarity 63, member B |
| FAM76A | family with sequence similarity 76, member A |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOXP3 | forkhead box P3 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GFER | growth factor, augmenter of liver regeneration |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HOXA10 | homeobox A10 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL25 | interleukin 25 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA0368 | KIAA0368 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LSP1 | lymphocyte-specific protein 1 |
| LY9 | lymphocyte antigen 9 |
| LYZL6 | lysozyme-like 6 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MED16 | mediator complex subunit 16 |
| MON2 | MON2 homolog (S. cerevisiae) |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MXRA8 | matrix-remodelling associated 8 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NELL2 | NEL-like 2 (chicken) |
| NMT2 | N-myristoyltransferase 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUP54 | nucleoporin 54kDa |
| NYNRIN | NYN domain and retroviral integrase containing |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE10A | phosphodiesterase 10A |
| PDE9A | phosphodiesterase 9A |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POU2F3 | POU class 2 homeobox 3 |
| PTCH1 | patched 1 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIOK3 | RIO kinase 3 |
| RNF17 | ring finger protein 17 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERHL2 | serine hydrolase-like 2 |
| SIRT5 | sirtuin 5 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SRPK3 | SRSF protein kinase 3 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STK17B | serine/threonine kinase 17b |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
| TECTA | tectorin alpha |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNPO2 | transportin 2 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TUBA4B | tubulin, alpha 4b |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF235 | zinc finger protein 235 |
| ZNF507 | zinc finger protein 507 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALOX12 | arachidonate 12-lipoxygenase |
| AXIN1 | axin 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNO | cyclin O |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRY2 | cryptochrome circadian clock 2 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DBF4B | DBF4 zinc finger B |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DMTN | dematin actin binding protein |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DRD1 | dopamine receptor D1 |
| DUSP9 | dual specificity phosphatase 9 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENO3 | enolase 3 (beta, muscle) |
| FGL1 | fibrinogen-like 1 |
| FRMD1 | FERM domain containing 1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMPR | guanosine monophosphate reductase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BM | histone cluster 1, H2bm |
| HSF4 | heat shock transcription factor 4 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYI | hydroxypyruvate isomerase (putative) |
| IL22 | interleukin 22 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0125 | KIAA0125 |
| KIF13B | kinesin family member 13B |
| KLK8 | kallikrein-related peptidase 8 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP2 | matrix metallopeptidase 2 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MUC3A | mucin 3A, cell surface associated |
| MUC3B | mucin 3B, cell surface associated |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKX3-2 | NK3 homeobox 2 |
| NPPA | natriuretic peptide A |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PICK1 | protein interacting with PRKCA 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNB3 | plexin B3 |
| PMCH | pro-melanin-concentrating hormone |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| S100A4 | S100 calcium binding protein A4 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMIM14 | small integral membrane protein 14 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOAT2 | sterol O-acyltransferase 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STK16 | serine/threonine kinase 16 |
| SYNC | syncoilin, intermediate filament protein |
| TARP | TCR gamma alternate reading frame protein |
| TBX19 | T-box 19 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VIM | vimentin |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZIC3 | Zic family member 3 |
| ZNF41 | zinc finger protein 41 |
