| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the spiradoline-4375 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADCK4 | aarF domain containing kinase 4 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATN1 | atrophin 1 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BTNL3 | butyrophilin-like 3 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| CALCR | calcitonin receptor |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CEMP1 | cementum protein 1 |
| CHI3L2 | chitinase 3-like 2 |
| CLEC4E | C-type lectin domain family 4, member E |
| CNTLN | centlein, centrosomal protein |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DTNA | dystrobrevin, alpha |
| ECE1 | endothelin converting enzyme 1 |
| EDNRA | endothelin receptor type A |
| EMID1 | EMI domain containing 1 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FOXG1 | forkhead box G1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GP5 | glycoprotein V (platelet) |
| GPM6B | glycoprotein M6B |
| GPR182 | G protein-coupled receptor 182 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HFE | hemochromatosis |
| ICOSLG | inducible T-cell co-stimulator ligand |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IFI44 | interferon-induced protein 44 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| ING4 | inhibitor of growth family, member 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KIAA1456 | KIAA1456 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LTB4R | leukotriene B4 receptor |
| LYZL6 | lysozyme-like 6 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MR1 | major histocompatibility complex, class I-related |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MVB12B | multivesicular body subunit 12B |
| MXD4 | MAX dimerization protein 4 |
| MYO15B | myosin XVB |
| NKX2-8 | NK2 homeobox 8 |
| NPAS2 | neuronal PAS domain protein 2 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PCDHA5 | protocadherin alpha 5 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POU3F4 | POU class 3 homeobox 4 |
| PRKCI | protein kinase C, iota |
| PRSS53 | protease, serine, 53 |
| PTHLH | parathyroid hormone-like hormone |
| RANBP3 | RAN binding protein 3 |
| RGS4 | regulator of G-protein signaling 4 |
| RIOK3 | RIO kinase 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPL10 | ribosomal protein L10 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SHOX2 | short stature homeobox 2 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TAGLN3 | transgelin 3 |
| TBX3 | T-box 3 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TDRD12 | tudor domain containing 12 |
| THRB | thyroid hormone receptor, beta |
| TLK1 | tousled-like kinase 1 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TRIM10 | tripartite motif containing 10 |
| TRIM36 | tripartite motif containing 36 |
| USP22 | ubiquitin specific peptidase 22 |
| ZG16 | zymogen granule protein 16 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALOX15 | arachidonate 15-lipoxygenase |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BCO1 | beta-carotene oxygenase 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| CARTPT | CART prepropeptide |
| CD70 | CD70 molecule |
| CEL | carboxyl ester lipase |
| CFHR4 | complement factor H-related 4 |
| CIDEC | cell death-inducing DFFA-like effector c |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CTSF | cathepsin F |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DRD1 | dopamine receptor D1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENO3 | enolase 3 (beta, muscle) |
| EXOSC1 | exosome component 1 |
| FBXO2 | F-box protein 2 |
| FGF22 | fibroblast growth factor 22 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FSTL1 | follistatin-like 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GPR1 | G protein-coupled receptor 1 |
| GPR85 | G protein-coupled receptor 85 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HDAC5 | histone deacetylase 5 |
| HDAC7 | histone deacetylase 7 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HOXD11 | homeobox D11 |
| IFNA14 | interferon, alpha 14 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL2 | interleukin 2 |
| ISL1 | ISL LIM homeobox 1 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1462 | KIAA1462 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LMTK1 | lemur tail kinase 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAL | mal, T-cell differentiation protein |
| MAPK10 | mitogen-activated protein kinase 10 |
| MMP3 | matrix metallopeptidase 3 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| NAG18 | NAG18 mRNA |
| NNAT | neuronatin |
| NTF3 | neurotrophin 3 |
| OVOL1 | ovo-like zinc finger 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POU3F2 | POU class 3 homeobox 2 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETBP1 | SET binding protein 1 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SSTR5 | somatostatin receptor 5 |
| STON1 | stonin 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D2 | TBC1 domain family, member 2 |
| TEX14 | testis expressed 14 |
| TEX15 | testis expressed 15 |
| THAP9 | THAP domain containing 9 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM40 | transmembrane protein 40 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRIM68 | tripartite motif containing 68 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VNN2 | vanin 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF532 | zinc finger protein 532 |
