| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the spiradoline-4553 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM28 | ADAM metallopeptidase domain 28 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BMP8A | bone morphogenetic protein 8a |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC181 | coiled-coil domain containing 181 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN18 | claudin 18 |
| CNN1 | calponin 1, basic, smooth muscle |
| CNTNAP2 | contactin associated protein-like 2 |
| COL7A1 | collagen, type VII, alpha 1 |
| CYB5R2 | cytochrome b5 reductase 2 |
| CYTH1 | cytohesin 1 |
| CYTH4 | cytohesin 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| DOK3 | docking protein 3 |
| DPYS | dihydropyrimidinase |
| DRP2 | dystrophin related protein 2 |
| ELK1 | ELK1, member of ETS oncogene family |
| ELL | elongation factor RNA polymerase II |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXO22 | F-box protein 22 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FCMR | Fc fragment of IgM receptor |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FYB | FYN binding protein |
| GAS7 | growth arrest-specific 7 |
| GK2 | glycerol kinase 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR19 | G protein-coupled receptor 19 |
| HDAC11 | histone deacetylase 11 |
| HES2 | hes family bHLH transcription factor 2 |
| HGFAC | HGF activator |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL15 | interleukin 15 |
| IL33R | interleukin 33 receptor |
| INO80D | INO80 complex subunit D |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA1107 | KIAA1107 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLF4 | Kruppel-like factor 4 (gut) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOXL3 | lysyl oxidase-like 3 |
| MAGEB2 | melanoma antigen family B2 |
| MCPH1 | microcephalin 1 |
| MLXIP | MLX interacting protein |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCAM1 | neural cell adhesion molecule 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDPN | podoplanin |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PIP | prolactin-induced protein |
| POU6F1 | POU class 6 homeobox 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PROX1 | prospero homeobox 1 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RUNX1 | runt-related transcription factor 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SIRPA | signal-regulatory protein alpha |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPRR2B | small proline-rich protein 2B |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STK17B | serine/threonine kinase 17b |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TBR1 | T-box, brain, 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| ZNF219 | zinc finger protein 219 |
| ZNF44 | zinc finger protein 44 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C1S | complement component 1, s subcomponent |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CEP131 | centrosomal protein 131kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CNN2 | calponin 2 |
| CPNE7 | copine VII |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYBRD1 | cytochrome b reductase 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNM3 | dynamin 3 |
| ECM1 | extracellular matrix protein 1 |
| EFNA3 | ephrin-A3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EN2 | engrailed homeobox 2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM120C | family with sequence similarity 120C |
| FAM53B | family with sequence similarity 53, member B |
| FMO4 | flavin containing monooxygenase 4 |
| FOXK2 | forkhead box K2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| HDAC5 | histone deacetylase 5 |
| HHLA3 | HERV-H LTR-associating 3 |
| HINFP | histone H4 transcription factor |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXB5 | homeobox B5 |
| HOXC4 | homeobox C4 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL15RA | interleukin 15 receptor, alpha |
| IL17RA | interleukin 17 receptor A |
| IRF1 | interferon regulatory factor 1 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| JUNB | jun B proto-oncogene |
| KIF16B | kinesin family member 16B |
| KLF3 | Kruppel-like factor 3 (basic) |
| LMNB2 | lamin B2 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG4 | NDRG family member 4 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OLFML3 | olfactomedin-like 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSBP2 | oxysterol binding protein 2 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLAC8 | placenta-specific 8 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| PORCN | porcupine homolog (Drosophila) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKX | protein kinase, X-linked |
| PRPF39 | pre-mRNA processing factor 39 |
| PRSS8 | protease, serine, 8 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF122 | ring finger protein 122 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCIN | scinderin |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SYT17 | synaptotagmin XVII |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TESK1 | testis-specific kinase 1 |
| TMEM57 | transmembrane protein 57 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| ULBP2 | UL16 binding protein 2 |
| WDR18 | WD repeat domain 18 |
| WDR76 | WD repeat domain 76 |
| WDR91 | WD repeat domain 91 |
| XAB2 | XPA binding protein 2 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |
