| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the spiramycin-2558 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTN2 | actinin, alpha 2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ANGPTL2 | angiopoietin-like 2 |
| AREG | amphiregulin |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ASPH | aspartate beta-hydroxylase |
| ATP10B | ATPase, class V, type 10B |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCNK | cyclin K |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CD84 | CD84 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL8A1 | collagen, type VIII, alpha 1 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSNK1E | casein kinase 1, epsilon |
| CTSZ | cathepsin Z |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DAPK3 | death-associated protein kinase 3 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPS8L1 | EPS8-like 1 |
| FBXO22 | F-box protein 22 |
| FLJ11292 | |
| FRMD8 | FERM domain containing 8 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPR4 | G protein-coupled receptor 4 |
| HIST1H2BC | histone cluster 1, H2bc |
| HOPX | HOP homeobox |
| HOXA10 | homeobox A10 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INCENP | inner centromere protein antigens 135/155kDa |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0226 | KIAA0226 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL20 | kelch-like family member 20 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMA2 | laminin, alpha 2 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| MAGED2 | melanoma antigen family D2 |
| MAP7 | microtubule-associated protein 7 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MYLK | myosin light chain kinase |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NID1 | nidogen 1 |
| NPEPL1 | aminopeptidase-like 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PEG3 | paternally expressed 3 |
| PIGR | polymeric immunoglobulin receptor |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RGS10 | regulator of G-protein signaling 10 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RUNX1 | runt-related transcription factor 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC38A7 | solute carrier family 38, member 7 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SP1 | Sp1 transcription factor |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TLN2 | talin 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM19 | transmembrane protein 19 |
| TP63 | tumor protein p63 |
| TRAF1 | TNF receptor-associated factor 1 |
| TYR | tyrosinase |
| UBOX5 | U-box domain containing 5 |
| USP29 | ubiquitin specific peptidase 29 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XDH | xanthine dehydrogenase |
| YLPM1 | YLP motif containing 1 |
| ZFHX4 | zinc finger homeobox 4 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF749 | zinc finger protein 749 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOL6 | apolipoprotein L, 6 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C5 | complement component 5 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBX8 | chromobox homolog 8 |
| CD9 | CD9 molecule |
| CEL | carboxyl ester lipase |
| CELP | carboxyl ester lipase pseudogene |
| CFP | complement factor properdin |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRYGC | crystallin, gamma C |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYM | dymeclin |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| FAM13C | family with sequence similarity 13, member C |
| FBRS | fibrosin |
| FJX1 | four jointed box 1 (Drosophila) |
| FMOD | fibromodulin |
| GOLGA8B | golgin A8 family, member B |
| GRPR | gastrin-releasing peptide receptor |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL11RA | interleukin 11 receptor, alpha |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| JAM3 | junctional adhesion molecule 3 |
| KIAA0319L | KIAA0319-like |
| KIF17 | kinesin family member 17 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MMP9 | matrix metallopeptidase 9 |
| MRAS | muscle RAS oncogene homolog |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MTSS1L | metastasis suppressor 1-like |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDE8B | phosphodiesterase 8B |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POLL | polymerase (DNA directed), lambda |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR7 | proline rich 7 (synaptic) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RAB3A | RAB3A, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SH2D3C | SH2 domain containing 3C |
| SHARPIN | SHANK-associated RH domain interactor |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPIDR | scaffolding protein involved in DNA repair |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STBD1 | starch binding domain 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAGLN | transgelin |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPCN1 | two pore segment channel 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TXLNG | taxilin gamma |
| UCN | urocortin |
| UPB1 | ureidopropionase, beta |
| WWC3 | WWC family member 3 |
| ZNF280A | zinc finger protein 280A |
| ZNF76 | zinc finger protein 76 |
| ZNF816 | zinc finger protein 816 |
| ZNF862 | zinc finger protein 862 |