spiramycin-3419 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the spiramycin-3419 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP1 Rho GTPase activating protein 1
ARSB arylsulfatase B
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPH aspartate beta-hydroxylase
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BICD1 bicaudal D homolog 1 (Drosophila)
BIRC7 baculoviral IAP repeat containing 7
C3 complement component 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC68 coiled-coil domain containing 68
CD82 CD82 molecule
COL6A1 collagen, type VI, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRY2 cryptochrome circadian clock 2
CTNS cystinosin, lysosomal cystine transporter
DBT dihydrolipoamide branched chain transacylase E2
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DIXDC1 DIX domain containing 1
ELSPBP1 epididymal sperm binding protein 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXTL3 exostosin-like glycosyltransferase 3
FBXL6 F-box and leucine-rich repeat protein 6
FBXO9 F-box protein 9
FCMR Fc fragment of IgM receptor
FGL1 fibrinogen-like 1
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-C major histocompatibility complex, class I, C
HR hair growth associated
IDI2-AS1 IDI2 antisense RNA 1
INPP1 inositol polyphosphate-1-phosphatase
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITFG2 integrin alpha FG-GAP repeat containing 2
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLHL25 kelch-like family member 25
KLHL35 kelch-like family member 35
KRT17 keratin 17, type I
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LMNA lamin A/C
LOC399491
LOC647070 uncharacterized LOC647070
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP2 low density lipoprotein receptor-related protein 2
LRRC61 leucine rich repeat containing 61
LTBP4 latent transforming growth factor beta binding protein 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP9 microtubule-associated protein 9
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MGC12488
MIA3 melanoma inhibitory activity family, member 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MOSPD3 motile sperm domain containing 3
MVB12B multivesicular body subunit 12B
MXD3 MAX dimerization protein 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEUROD1 neuronal differentiation 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARVA parvin, alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RAB3A RAB3A, member RAS oncogene family
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
REPS1 RALBP1 associated Eps domain containing 1
RHOQ ras homolog family member Q
RNF24 ring finger protein 24
RPS4Y1 ribosomal protein S4, Y-linked 1
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMR3A submaxillary gland androgen regulated protein 3A
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPON2 spondin 2, extracellular matrix protein
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SUGP1 SURP and G patch domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TMEM144 transmembrane protein 144
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR55 WD repeat domain 55
WSCD1 WSC domain containing 1
ZNF10 zinc finger protein 10
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD14A abhydrolase domain containing 14A
ABLIM3 actin binding LIM protein family, member 3
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARRB1 arrestin, beta 1
ATXN2 ataxin 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BFSP1 beaded filament structural protein 1, filensin
C12ORF4 chromosome 12 open reading frame 4
C2ORF44 chromosome 2 open reading frame 44
CALCOCO1 calcium binding and coiled-coil domain 1
CASD1 CAS1 domain containing 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CCDC109B coiled-coil domain containing 109B
CDR2L cerebellar degeneration-related protein 2-like
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLK1 CDC-like kinase 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CORO1A coronin, actin binding protein, 1A
EFHD2 EF-hand domain family, member D2
ENO2 enolase 2 (gamma, neuronal)
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
EXOSC9 exosome component 9
FER fer (fps/fes related) tyrosine kinase
FGGY FGGY carbohydrate kinase domain containing
GCHFR GTP cyclohydrolase I feedback regulator
GDAP1 ganglioside induced differentiation associated protein 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
HIRA histone cell cycle regulator
IFT81 intraflagellar transport 81
IGFBP6 insulin-like growth factor binding protein 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KDM5C lysine (K)-specific demethylase 5C
KIZ kizuna centrosomal protein
KLF3 Kruppel-like factor 3 (basic)
KLHL26 kelch-like family member 26
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRP3 low density lipoprotein receptor-related protein 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MFSD10 major facilitator superfamily domain containing 10
MITF microphthalmia-associated transcription factor
MMP9 matrix metallopeptidase 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTRF1 mitochondrial translational release factor 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1D myosin ID
MYO1F myosin IF
NABP2 nucleic acid binding protein 2
NDRG1 N-myc downstream regulated 1
OLFML3 olfactomedin-like 3
PARD6B par-6 family cell polarity regulator beta
PIBF1 progesterone immunomodulatory binding factor 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PODXL2 podocalyxin-like 2
PRR7 proline rich 7 (synaptic)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTDSS2 phosphatidylserine synthase 2
PYCRL pyrroline-5-carboxylate reductase-like
RECQL4 RecQ protein-like 4
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RRAGB Ras-related GTP binding B
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP5 secretory carrier membrane protein 5
SHARPIN SHANK-associated RH domain interactor
SIK1 salt-inducible kinase 1
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC35A5 solute carrier family 35, member A5
SPATA2L spermatogenesis associated 2-like
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
THOP1 thimet oligopeptidase 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TM6SF1 transmembrane 6 superfamily member 1
TMEM104 transmembrane protein 104
TMSB15A thymosin beta 15a
TRABD TraB domain containing
TSPAN1 tetraspanin 1
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
VWA1 von Willebrand factor A domain containing 1
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
ZBTB3 zinc finger and BTB domain containing 3
ZC3H3 zinc finger CCCH-type containing 3
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF350 zinc finger protein 350
ZNF430 zinc finger protein 430
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF721 zinc finger protein 721
ZNF862 zinc finger protein 862