spiramycin-3762 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the spiramycin-3762 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADRA2C adrenoceptor alpha 2C
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANGPTL2 angiopoietin-like 2
ANKRD55 ankyrin repeat domain 55
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOL3 apolipoprotein L, 3
ATP10A ATPase, class V, type 10A
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAIAP2 BAI1-associated protein 2
BBC3 BCL2 binding component 3
BTNL3 butyrophilin-like 3
C1ORF95 chromosome 1 open reading frame 95
C5ORF45 chromosome 5 open reading frame 45
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARTPT CART prepropeptide
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CEMIP cell migration inducing protein, hyaluronan binding
CEP41 centrosomal protein 41kDa
CERS4 ceramide synthase 4
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DBP D site of albumin promoter (albumin D-box) binding protein
DLG4 discs, large homolog 4 (Drosophila)
ELN elastin
ELOVL5 ELOVL fatty acid elongase 5
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
FAM49B family with sequence similarity 49, member B
FLRT2 fibronectin leucine rich transmembrane protein 2
FNDC4 fibronectin type III domain containing 4
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FRMD4B FERM domain containing 4B
FYB FYN binding protein
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GPR135 G protein-coupled receptor 135
H2AFX H2A histone family, member X
HFE hemochromatosis
HRASLS2 HRAS-like suppressor 2
HRG histidine-rich glycoprotein
IFNA16 interferon, alpha 16
INSL4 insulin-like 4 (placenta)
KIF1C kinesin family member 1C
KLK10 kallikrein-related peptidase 10
KLK2 kallikrein-related peptidase 2
KLK7 kallikrein-related peptidase 7
KRT2 keratin 2, type II
KSR1 kinase suppressor of ras 1
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LOXL2 lysyl oxidase-like 2
MAGEA5 melanoma antigen family A5
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MIER2 mesoderm induction early response 1, family member 2
MMP11 matrix metallopeptidase 11
MUC3B mucin 3B, cell surface associated
MYO7A myosin VIIA
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPR1 natriuretic peptide receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLAH oleoyl-ACP hydrolase
PCDH7 protocadherin 7
PF4 platelet factor 4
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PON1 paraoxonase 1
POU3F4 POU class 3 homeobox 4
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB5C RAB5C, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RNF208 ring finger protein 208
SCN1B sodium channel, voltage gated, type I beta subunit
SFTPB surfactant protein B
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SOS2 son of sevenless homolog 2 (Drosophila)
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAGLN3 transgelin 3
TAT tyrosine aminotransferase
TBCD tubulin folding cofactor D
TESPA1 thymocyte expressed, positive selection associated 1
TLX2 T-cell leukemia homeobox 2
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP5 vesicle-associated membrane protein 5
ZC3H13 zinc finger CCCH-type containing 13
ZNF362 zinc finger protein 362
ZNF506 zinc finger protein 506
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACSS3 acyl-CoA synthetase short-chain family member 3
AKAP5 A kinase (PRKA) anchor protein 5
AMDHD2 amidohydrolase domain containing 2
ANXA10 annexin A10
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOL6 apolipoprotein L, 6
APOLD1 apolipoprotein L domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHD1 bromo adjacent homology domain containing 1
BMP4 bone morphogenetic protein 4
C16ORF59 chromosome 16 open reading frame 59
C17ORF53 chromosome 17 open reading frame 53
C19ORF40 chromosome 19 open reading frame 40
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CCDC106 coiled-coil domain containing 106
CCDC85C coiled-coil domain containing 85C
CINP cyclin-dependent kinase 2 interacting protein
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL9A2 collagen, type IX, alpha 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL3 chemokine (C-X-C motif) ligand 3
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
EFNA3 ephrin-A3
EGLN3 egl-9 family hypoxia-inducible factor 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM204A family with sequence similarity 204, member A
GAS8 growth arrest-specific 8
GLS2 glutaminase 2 (liver, mitochondrial)
GMPR guanosine monophosphate reductase
GSDMD gasdermin D
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA7 homeobox A7
HOXB2 homeobox B2
HOXC11 homeobox C11
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INO80D INO80 complex subunit D
IPO8 importin 8
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM8 lysine (K)-specific demethylase 8
LINC00472 long intergenic non-protein coding RNA 472
LINS lines homolog (Drosophila)
LNPEP leucyl/cystinyl aminopeptidase
LOC100127972 uncharacterized LOC100127972
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
MMP3 matrix metallopeptidase 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NARFL nuclear prelamin A recognition factor-like
NECAP2 NECAP endocytosis associated 2
OGDHL oxoglutarate dehydrogenase-like
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P3H2 prolyl 3-hydroxylase 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PHF14 PHD finger protein 14
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMCH pro-melanin-concentrating hormone
PTGES2 prostaglandin E synthase 2
QPCTL glutaminyl-peptide cyclotransferase-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RPL10L ribosomal protein L10-like
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SCG2 secretogranin II
SCIN scinderin
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SNHG20 small nucleolar RNA host gene 20
SNORA21 small nucleolar RNA, H/ACA box 21
ST5 suppression of tumorigenicity 5
STRN striatin, calmodulin binding protein
TIGD6 tigger transposable element derived 6
TMC5 transmembrane channel-like 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN2 tetraspanin 2
UNC119 unc-119 homolog (C. elegans)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
ZNF37BP zinc finger protein 37B, pseudogene
ZNF415 zinc finger protein 415
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862