| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the spiramycin-3938 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM7 | ADAM metallopeptidase domain 7 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANGPT4 | angiopoietin 4 |
| ANKRD55 | ankyrin repeat domain 55 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ART1 | ADP-ribosyltransferase 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CELF2 | CUGBP, Elav-like family member 2 |
| CNGB1 | cyclic nucleotide gated channel beta 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCTN2 | dynactin 2 (p50) |
| DFNA5 | deafness, autosomal dominant 5 |
| DFNB31 | deafness, autosomal recessive 31 |
| DIO2 | deiodinase, iodothyronine, type II |
| DLX2 | distal-less homeobox 2 |
| DNASE1 | deoxyribonuclease I |
| EFCAB11 | EF-hand calcium binding domain 11 |
| FBN1 | fibrillin 1 |
| GHRH | growth hormone releasing hormone |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR135 | G protein-coupled receptor 135 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM8 | glutamate receptor, metabotropic 8 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HERC2P3 | hect domain and RLD 2 pseudogene 3 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA1 | homeobox A1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IQCC | IQ motif containing C |
| IRF4 | interferon regulatory factor 4 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KIAA1324 | KIAA1324 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LIMK1 | LIM domain kinase 1 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LY86 | lymphocyte antigen 86 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MBD2 | methyl-CpG binding domain protein 2 |
| MC5R | melanocortin 5 receptor |
| MPPE1 | metallophosphoesterase 1 |
| MUC8 | mucin 8 |
| NPAS3 | neuronal PAS domain protein 3 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 |
| NRL | neural retina leucine zipper |
| NTM | neurotrimin |
| P2RX2 | purinergic receptor P2X, ligand gated ion channel, 2 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAPPA2 | pappalysin 2 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLK3 | polo-like kinase 3 |
| PMEL | premelanosome protein |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POLL | polymerase (DNA directed), lambda |
| POU2F2 | POU class 2 homeobox 2 |
| PTAFR | platelet-activating factor receptor |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC26A4 | solute carrier family 26 (anion exchanger), member 4 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TAZ | tafazzin |
| TFEB | transcription factor EB |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTPA | tocopherol (alpha) transfer protein |
| UBE3A | ubiquitin protein ligase E3A |
| UBXN1 | UBX domain protein 1 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACPP | acid phosphatase, prostate |
| ACTL8 | actin-like 8 |
| ADCK4 | aarF domain containing kinase 4 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCL2L2 | BCL2-like 2 |
| BMP15 | bone morphogenetic protein 15 |
| BMP4 | bone morphogenetic protein 4 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC71 | coiled-coil domain containing 71 |
| CCNK | cyclin K |
| CD34 | CD34 molecule |
| CFHR4 | complement factor H-related 4 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLEC4E | C-type lectin domain family 4, member E |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DLL3 | delta-like 3 (Drosophila) |
| DRD1 | dopamine receptor D1 |
| DYM | dymeclin |
| EGFL7 | EGF-like-domain, multiple 7 |
| FAM120C | family with sequence similarity 120C |
| FANCC | Fanconi anemia, complementation group C |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GK3P | glycerol kinase 3 pseudogene |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR143 | G protein-coupled receptor 143 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2AK | histone cluster 1, H2ak |
| HOXA4 | homeobox A4 |
| HOXC11 | homeobox C11 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFI35 | interferon-induced protein 35 |
| IFNA17 | interferon, alpha 17 |
| ITGA10 | integrin, alpha 10 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| KIF13A | kinesin family member 13A |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL25 | kelch-like family member 25 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MOB3B | MOB kinase activator 3B |
| MOCS3 | molybdenum cofactor synthesis 3 |
| NELL2 | NEL-like 2 (chicken) |
| ONECUT2 | one cut homeobox 2 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POPDC3 | popeye domain containing 3 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RFXAP | regulatory factor X-associated protein |
| RGS2 | regulator of G-protein signaling 2 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC17A2 | solute carrier family 17, member 2 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TAOK1 | TAO kinase 1 |
| TARP | TCR gamma alternate reading frame protein |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TBX3 | T-box 3 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM19 | transmembrane protein 19 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF484 | zinc finger protein 484 |
| ZNF551 | zinc finger protein 551 |
| ZNF652 | zinc finger protein 652 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |
| ZW10 | zw10 kinetochore protein |