| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the spiramycin-4319 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ARTN | artemin |
| ATP11A | ATPase, class VI, type 11A |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| B9D1 | B9 protein domain 1 |
| B9D2 | B9 protein domain 2 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| BTD | biotinidase |
| CALU | calumenin |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CDK10 | cyclin-dependent kinase 10 |
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL4A1 | collagen, type IV, alpha 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DMBT1 | deleted in malignant brain tumors 1 |
| DOK4 | docking protein 4 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP3 | dual specificity phosphatase 3 |
| EDN1 | endothelin 1 |
| ELMO2 | engulfment and cell motility 2 |
| FHL1 | four and a half LIM domains 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR137 | G protein-coupled receptor 137 |
| GPR19 | G protein-coupled receptor 19 |
| GRK4 | G protein-coupled receptor kinase 4 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HAP1 | huntingtin-associated protein 1 |
| HDAC11 | histone deacetylase 11 |
| IL11 | interleukin 11 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KIAA1644 | KIAA1644 |
| KITLG | KIT ligand |
| KLHL22 | kelch-like family member 22 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LPIN1 | lipin 1 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MEF2D | myocyte enhancer factor 2D |
| MFAP3 | microfibrillar-associated protein 3 |
| MLXIP | MLX interacting protein |
| MTMR1 | myotubularin related protein 1 |
| MUC7 | mucin 7, secreted |
| NBEAL2 | neurobeachin-like 2 |
| NCOA3 | nuclear receptor coactivator 3 |
| NEK9 | NIMA-related kinase 9 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| OLFML2B | olfactomedin-like 2B |
| OPRL1 | opiate receptor-like 1 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PAX9 | paired box 9 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLA1A | phospholipase A1 member A |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK4 | polo-like kinase 4 |
| POLM | polymerase (DNA directed), mu |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB2A | RAB2A, member RAS oncogene family |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS14 | regulator of G-protein signaling 14 |
| RGS5 | regulator of G-protein signaling 5 |
| RPL23 | ribosomal protein L23 |
| RXRB | retinoid X receptor, beta |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIRPA | signal-regulatory protein alpha |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SORT1 | sortilin 1 |
| SP1 | Sp1 transcription factor |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| STC1 | stanniocalcin 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBC1D30 | TBC1 domain family, member 30 |
| TBC1D5 | TBC1 domain family, member 5 |
| TLE4 | transducin-like enhancer of split 4 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNPO2 | transportin 2 |
| TNXB | tenascin XB |
| VPRBP | Vpr (HIV-1) binding protein |
| WT1 | Wilms tumor 1 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF24 | zinc finger protein 24 |
| ZNF639 | zinc finger protein 639 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ALPK1 | alpha-kinase 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ATG10 | autophagy related 10 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBX8 | chromobox homolog 8 |
| CCNE1 | cyclin E1 |
| CD101 | CD101 molecule |
| CD53 | CD53 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CPNE7 | copine VII |
| CRMP1 | collapsin response mediator protein 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNM3 | dynamin 3 |
| DOC2A | double C2-like domains, alpha |
| EFNB1 | ephrin-B1 |
| FAM120C | family with sequence similarity 120C |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FLT4 | fms-related tyrosine kinase 4 |
| FZD10 | frizzled class receptor 10 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSTM5 | glutathione S-transferase mu 5 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H4C | histone cluster 1, H4c |
| HOXC11 | homeobox C11 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL2 | interleukin 2 |
| IL24 | interleukin 24 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA0894 | KIAA0894 protein |
| KIRREL | kin of IRRE like (Drosophila) |
| KLHL28 | kelch-like family member 28 |
| LAMC3 | laminin, gamma 3 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRRC6 | leucine rich repeat containing 6 |
| LYRM9 | LYR motif containing 9 |
| MBTD1 | mbt domain containing 1 |
| MDM4 | MDM4, p53 regulator |
| MED18 | mediator complex subunit 18 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTA2 | metastasis associated 1 family, member 2 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NID2 | nidogen 2 (osteonidogen) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PLSCR2 | phospholipid scramblase 2 |
| POLL | polymerase (DNA directed), lambda |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRR14L | proline rich 14-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBBP5 | retinoblastoma binding protein 5 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPGRIP1L | RPGRIP1-like |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SPIN1 | spindlin 1 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TCP11 | t-complex 11, testis-specific |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TEP1 | telomerase-associated protein 1 |
| TLN1 | talin 1 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF264 | zinc finger protein 264 |
| ZNF652 | zinc finger protein 652 |
| ZNF669 | zinc finger protein 669 |
| ZNF721 | zinc finger protein 721 |