| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the spironolactone-1380 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
| ANXA11 | annexin A11 |
| APOL2 | apolipoprotein L, 2 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BBS4 | Bardet-Biedl syndrome 4 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CACYBP | calcyclin binding protein |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CBX5 | chromobox homolog 5 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DERL2 | derlin 2 |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DSCR3 | Down syndrome critical region 3 |
| DUS2 | dihydrouridine synthase 2 |
| DUSP10 | dual specificity phosphatase 10 |
| FAM153A | family with sequence similarity 153, member A |
| FAM63A | family with sequence similarity 63, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FBXO3 | F-box protein 3 |
| FLNB | filamin B, beta |
| GLRX3 | glutaredoxin 3 |
| GLS | glutaminase |
| GUK1 | guanylate kinase 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HINFP | histone H4 transcription factor |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H4J | histone cluster 1, H4j |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| ICAM2 | intercellular adhesion molecule 2 |
| IL6ST | interleukin 6 signal transducer |
| KDM4C | lysine (K)-specific demethylase 4C |
| KIFC1 | kinesin family member C1 |
| KLHL26 | kelch-like family member 26 |
| KLHL36 | kelch-like family member 36 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 |
| MED18 | mediator complex subunit 18 |
| MYL10 | myosin, light chain 10, regulatory |
| NDRG2 | NDRG family member 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOAZFP | nucleolar atypical zinc finger |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) |
| OGFR | opioid growth factor receptor |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PEX10 | peroxisomal biogenesis factor 10 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLS1 | plastin 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRF1 | perforin 1 (pore forming protein) |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRPF39 | pre-mRNA processing factor 39 |
| PRRC2C | proline-rich coiled-coil 2C |
| PTX3 | pentraxin 3, long |
| RABGAP1 | RAB GTPase activating protein 1 |
| RETN | resistin |
| RHOD | ras homolog family member D |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| STK19 | serine/threonine kinase 19 |
| TAC3 | tachykinin 3 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TMEM259 | transmembrane protein 259 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TREX1 | three prime repair exonuclease 1 |
| TSPYL2 | TSPY-like 2 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZDHHC4 | zinc finger, DHHC-type containing 4 |
| ZGPAT | zinc finger, CCCH-type with G patch domain |
| ZNF688 | zinc finger protein 688 |
| ZNF804A | zinc finger protein 804A |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCKDK | branched chain ketoacid dehydrogenase kinase |
| BCORL1 | BCL6 corepressor-like 1 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| CCDC130 | coiled-coil domain containing 130 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPJ | centromere protein J |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNPY3 | canopy FGF signaling regulator 3 |
| COQ3 | coenzyme Q3 methyltransferase |
| CPOX | coproporphyrinogen oxidase |
| CRTAP | cartilage associated protein |
| CTAGE9 | CTAGE family, member 9 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CUTC | cutC copper transporter |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DEAF1 | DEAF1 transcription factor |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 |
| ECD | ecdysoneless homolog (Drosophila) |
| FAM46A | family with sequence similarity 46, member A |
| FHOD1 | formin homology 2 domain containing 1 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H2AFZ | H2A histone family, member Z |
| HDAC9 | histone deacetylase 9 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IL4R | interleukin 4 receptor |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| ING3 | inhibitor of growth family, member 3 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRF8 | interferon regulatory factor 8 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KDM3A | lysine (K)-specific demethylase 3A |
| LIMA1 | LIM domain and actin binding 1 |
| LYRM2 | LYR motif containing 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MCRS1 | microspherule protein 1 |
| MED23 | mediator complex subunit 23 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUBP1 | nucleotide binding protein 1 |
| NUBP2 | nucleotide binding protein 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIGR | polymeric immunoglobulin receptor |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPIEL | peptidylprolyl isomerase E-like pseudogene |
| PUS7 | pseudouridylate synthase 7 (putative) |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RFX7 | regulatory factor X, 7 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLN | sarcolipin |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| TEX40 | testis expressed 40 |
| TFB2M | transcription factor B2, mitochondrial |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TSC22D1 | TSC22 domain family, member 1 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTC27 | tetratricopeptide repeat domain 27 |
| UIMC1 | ubiquitin interaction motif containing 1 |
| XBP1 | X-box binding protein 1 |
| XPOT | exportin, tRNA |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZNF140 | zinc finger protein 140 |
| ZNF274 | zinc finger protein 274 |
| ZNF529 | zinc finger protein 529 |
