| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the spironolactone-2226 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACRV1 | acrosomal vesicle protein 1 |
| AIRE | autoimmune regulator |
| AK1 | adenylate kinase 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BCL2 | B-cell CLL/lymphoma 2 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CD248 | CD248 molecule, endosialin |
| CD48 | CD48 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CNTN1 | contactin 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DRD2 | dopamine receptor D2 |
| EDNRA | endothelin receptor type A |
| EFNB3 | ephrin-B3 |
| EMC1 | ER membrane protein complex subunit 1 |
| FBXO4 | F-box protein 4 |
| FGF12 | fibroblast growth factor 12 |
| FRMD1 | FERM domain containing 1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GLRX | glutaredoxin (thioltransferase) |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GOLGA8A | golgin A8 family, member A |
| HBEGF | heparin-binding EGF-like growth factor |
| HFE | hemochromatosis |
| HHLA1 | HERV-H LTR-associating 1 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXA10 | homeobox A10 |
| HOXC5 | homeobox C5 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IL2RB | interleukin 2 receptor, beta |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ITGB4 | integrin, beta 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KEL | Kell blood group, metallo-endopeptidase |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MALL | mal, T-cell differentiation protein-like |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| METTL7A | methyltransferase like 7A |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MYH6 | myosin, heavy chain 6, cardiac muscle, alpha |
| MYL10 | myosin, light chain 10, regulatory |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCALD | neurocalcin delta |
| NF2 | neurofibromin 2 (merlin) |
| NPY2R | neuropeptide Y receptor Y2 |
| NXF2 | nuclear RNA export factor 2 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PARD6B | par-6 family cell polarity regulator beta |
| PGR | progesterone receptor |
| PHF8 | PHD finger protein 8 |
| PLCD1 | phospholipase C, delta 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PVR | poliovirus receptor |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAB6B | RAB6B, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RBM5 | RNA binding motif protein 5 |
| REEP2 | receptor accessory protein 2 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNF122 | ring finger protein 122 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT5 | sirtuin 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SMAD1 | SMAD family member 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TEX14 | testis expressed 14 |
| TGFA | transforming growth factor, alpha |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TNS1 | tensin 1 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRIM29 | tripartite motif containing 29 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| ZFHX2 | zinc finger homeobox 2 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| AXIN1 | axin 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCDC134 | coiled-coil domain containing 134 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD82 | CD82 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CEL | carboxyl ester lipase |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN1 | claudin 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK5 | docking protein 5 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGFL7 | EGF-like-domain, multiple 7 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM110B | family with sequence similarity 110, member B |
| FAM155A | family with sequence similarity 155, member A |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FBRS | fibrosin |
| FLT4 | fms-related tyrosine kinase 4 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRPR | gastrin-releasing peptide receptor |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H3E | histone cluster 1, H3e |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA0125 | KIAA0125 |
| KRT15 | keratin 15, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC49 | leucine rich repeat containing 49 |
| LRRC61 | leucine rich repeat containing 61 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MATK | megakaryocyte-associated tyrosine kinase |
| MCOLN1 | mucolipin 1 |
| MEIS2 | Meis homeobox 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYOZ1 | myozenin 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKX3-2 | NK3 homeobox 2 |
| NLRX1 | NLR family member X1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NXPH4 | neurexophilin 4 |
| OLFML2A | olfactomedin-like 2A |
| OVOL1 | ovo-like zinc finger 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PICK1 | protein interacting with PRKCA 1 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLAC1 | placenta-specific 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PODXL2 | podocalyxin-like 2 |
| POM121 | POM121 transmembrane nucleoporin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PROS1 | protein S (alpha) |
| PRSS22 | protease, serine, 22 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS20 | regulator of G-protein signaling 20 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLIT2 | slit homolog 2 (Drosophila) |
| SPRYD7 | SPRY domain containing 7 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D19 | TBC1 domain family, member 19 |
| TDRD1 | tudor domain containing 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRAIP | TRAF interacting protein |
| TUBA3C | tubulin, alpha 3c |
| TYRP1 | tyrosinase-related protein 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XDH | xanthine dehydrogenase |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF506 | zinc finger protein 506 |
| ZNF516 | zinc finger protein 516 |
| ZNF770 | zinc finger protein 770 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
