| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the spironolactone-5781 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| AAK1 | AP2 associated kinase 1 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADCK2 | aarF domain containing kinase 2 |
| AHNAK | AHNAK nucleoprotein |
| ANGPTL4 | angiopoietin-like 4 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP9A | ATPase, class II, type 9A |
| AVP | arginine vasopressin |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BEST2 | bestrophin 2 |
| BMP7 | bone morphogenetic protein 7 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CCDC57 | coiled-coil domain containing 57 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK10 | cyclin-dependent kinase 10 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLIC3 | chloride intracellular channel 3 |
| CLMN | calmin (calponin-like, transmembrane) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COLEC12 | collectin sub-family member 12 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| EDNRB | endothelin receptor type B |
| ELAC1 | elaC ribonuclease Z 1 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FGB | fibrinogen beta chain |
| FOXE1 | forkhead box E1 |
| FOXG1 | forkhead box G1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GK | glycerol kinase |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IL11 | interleukin 11 |
| IL21R | interleukin 21 receptor |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KIAA1107 | KIAA1107 |
| KLHL23 | kelch-like family member 23 |
| KRT34 | keratin 34, type I |
| KRTAP9-9 | keratin associated protein 9-9 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LEPR | leptin receptor |
| LINC01558 | long intergenic non-protein coding RNA 1558 |
| LMTK2 | lemur tyrosine kinase 2 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MEGF8 | multiple EGF-like-domains 8 |
| MFAP3 | microfibrillar-associated protein 3 |
| MOG | myelin oligodendrocyte glycoprotein |
| MORN1 | MORN repeat containing 1 |
| MT1G | metallothionein 1G |
| MTSS1L | metastasis suppressor 1-like |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NGF | nerve growth factor (beta polypeptide) |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PGM5 | phosphoglucomutase 5 |
| POU5F1B | POU class 5 homeobox 1B |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RASL11B | RAS-like, family 11, member B |
| REEP2 | receptor accessory protein 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RHEB | Ras homolog enriched in brain |
| RTCA | RNA 3'-terminal phosphate cyclase |
| SH3BP2 | SH3-domain binding protein 2 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STC1 | stanniocalcin 1 |
| STOML1 | stomatin (EPB72)-like 1 |
| SUSD5 | sushi domain containing 5 |
| TAGLN3 | transgelin 3 |
| TAT | tyrosine aminotransferase |
| TBC1D22B | TBC1 domain family, member 22B |
| TFCP2L1 | transcription factor CP2-like 1 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TUBA3C | tubulin, alpha 3c |
| UPK3B | uroplakin 3B |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF254 | zinc finger protein 254 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARMC6 | armadillo repeat containing 6 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BEND5 | BEN domain containing 5 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C5 | complement component 5 |
| CCDC71 | coiled-coil domain containing 71 |
| CCNJL | cyclin J-like |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CISH | cytokine inducible SH2-containing protein |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CTSF | cathepsin F |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXORF56 | chromosome X open reading frame 56 |
| DBF4B | DBF4 zinc finger B |
| DLL3 | delta-like 3 (Drosophila) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DOCK1 | dedicator of cytokinesis 1 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| FAM53B | family with sequence similarity 53, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR19 | G protein-coupled receptor 19 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HDAC5 | histone deacetylase 5 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H3C | histone cluster 1, H3c |
| HIST1H3G | histone cluster 1, H3g |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| ITK | IL2-inducible T-cell kinase |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KLHL3 | kelch-like family member 3 |
| KRT9 | keratin 9, type I |
| LAMC3 | laminin, gamma 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC257152 | uncharacterized LOC257152 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC6 | leucine rich repeat containing 6 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEF1 | melanoma antigen family F1 |
| MATN3 | matrilin 3 |
| MMRN2 | multimerin 2 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NCS1 | neuronal calcium sensor 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| ODF2 | outer dense fiber of sperm tails 2 |
| OSMR | oncostatin M receptor |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PC | pyruvate carboxylase |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PODXL2 | podocalyxin-like 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RNF2 | ring finger protein 2 |
| SECISBP2 | SECIS binding protein 2 |
| SESN1 | sestrin 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMAD7 | SMAD family member 7 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPRYD7 | SPRY domain containing 7 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TAGLN | transgelin |
| TBC1D17 | TBC1 domain family, member 17 |
| TEP1 | telomerase-associated protein 1 |
| TMEM212 | transmembrane protein 212 |
| TOM1 | target of myb1 (chicken) |
| TRABD | TraB domain containing |
| TRAF2 | TNF receptor-associated factor 2 |
| TUBA4B | tubulin, alpha 4b |
| WDR33 | WD repeat domain 33 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF215 | zinc finger protein 215 |
| ZNF230 | zinc finger protein 230 |
| ZNF286A | zinc finger protein 286A |
| ZNF358 | zinc finger protein 358 |
| ZNF385D | zinc finger protein 385D |
| ZNF671 | zinc finger protein 671 |
