| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the spironolactone-6255 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATP11A | ATPase, class VI, type 11A |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDHR1 | cadherin-related family member 1 |
| CEP162 | centrosomal protein 162kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL4A1 | collagen, type IV, alpha 1 |
| CST6 | cystatin E/M |
| CTSF | cathepsin F |
| DCN | decorin |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EFNA3 | ephrin-A3 |
| EMX1 | empty spiracles homeobox 1 |
| EPHB6 | EPH receptor B6 |
| EXOC7 | exocyst complex component 7 |
| EXPH5 | exophilin 5 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FCAR | Fc fragment of IgA receptor |
| FHIT | fragile histidine triad |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALR3 | galanin receptor 3 |
| GGT1 | gamma-glutamyltransferase 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTP1 | glutathione S-transferase pi 1 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HFE | hemochromatosis |
| HOXB7 | homeobox B7 |
| HOXC10 | homeobox C10 |
| HPSE2 | heparanase 2 (inactive) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGB8 | integrin, beta 8 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| KLHL22 | kelch-like family member 22 |
| LIMK2 | LIM domain kinase 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LMF2 | lipase maturation factor 2 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MAG | myelin associated glycoprotein |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP4 | microtubule-associated protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MID1 | midline 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MUC3B | mucin 3B, cell surface associated |
| MYOM2 | myomesin 2 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL12 | nucleolar protein 12 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OMG | oligodendrocyte myelin glycoprotein |
| PCGF2 | polycomb group ring finger 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLCH1 | phospholipase C, eta 1 |
| PLTP | phospholipid transfer protein |
| PLXNA1 | plexin A1 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDX2 | peroxiredoxin 2 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLAMF8 | SLAM family member 8 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPEF1 | sperm flagellar 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPPL2B | signal peptide peptidase like 2B |
| SRPK2 | SRSF protein kinase 2 |
| SSTR4 | somatostatin receptor 4 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like |
| TAPBP | TAP binding protein (tapasin) |
| TAT | tyrosine aminotransferase |
| TLE4 | transducin-like enhancer of split 4 |
| TP63 | tumor protein p63 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| USP34 | ubiquitin specific peptidase 34 |
| VDAC3 | voltage-dependent anion channel 3 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZNF35 | zinc finger protein 35 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARMC6 | armadillo repeat containing 6 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| AZI2 | 5-azacytidine induced 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C11ORF57 | chromosome 11 open reading frame 57 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CBR4 | carbonyl reductase 4 |
| CCDC25 | coiled-coil domain containing 25 |
| CD2AP | CD2-associated protein |
| CHMP7 | charged multivesicular body protein 7 |
| CHN1 | chimerin 1 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNM1 | dynamin 1 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM13B | family with sequence similarity 13, member B |
| FAM189B | family with sequence similarity 189, member B |
| FANCF | Fanconi anemia, complementation group F |
| FBRS | fibrosin |
| FCHO1 | FCH domain only 1 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FKBP5 | FK506 binding protein 5 |
| FOXA1 | forkhead box A1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GATA6 | GATA binding protein 6 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HMBOX1 | homeobox containing 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| IL17RA | interleukin 17 receptor A |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KDM3B | lysine (K)-specific demethylase 3B |
| KDM5C | lysine (K)-specific demethylase 5C |
| LAMA3 | laminin, alpha 3 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MED24 | mediator complex subunit 24 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| NBEAL2 | neurobeachin-like 2 |
| NCAM2 | neural cell adhesion molecule 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPAN | peter pan homolog (Drosophila) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAI14 | retinoic acid induced 14 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF146 | ring finger protein 146 |
| RNF219 | ring finger protein 219 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SETMAR | SET domain and mariner transposase fusion gene |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNX15 | sorting nexin 15 |
| SYNJ2BP | synaptojanin 2 binding protein |
| SYT17 | synaptotagmin XVII |
| TAGLN | transgelin |
| TBC1D13 | TBC1 domain family, member 13 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TMEM184B | transmembrane protein 184B |
| TPCN1 | two pore segment channel 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPAN1 | tetraspanin 1 |
| TTC26 | tetratricopeptide repeat domain 26 |
| UBXN8 | UBX domain protein 8 |
| USP18 | ubiquitin specific peptidase 18 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF408 | zinc finger protein 408 |
| ZNF668 | zinc finger protein 668 |
| ZNF7 | zinc finger protein 7 |
| ZNF768 | zinc finger protein 768 |
| ZNF813 | zinc finger protein 813 |
| ZNF839 | zinc finger protein 839 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
