spleen Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A highly vascular ductless organ that is located in the left abdominal region near the stomach or intestine of most vertebrates and is concerned with final destruction of red blood cells, filtration and storage of blood, and production of lymphocytes. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001281)
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Genes

79 genes co-occuring with the biological term spleen in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ARMC3 armadillo repeat containing 3
BCL2 B-cell CLL/lymphoma 2
C3 complement component 3
CCNT1 cyclin T1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD207 CD207 molecule, langerin
CD4 CD4 molecule
CD68 CD68 molecule
CD81 CD81 molecule
CHODL chondrolectin
CMKLR1 chemerin chemokine-like receptor 1
CREM cAMP responsive element modulator
CSF3 colony stimulating factor 3 (granulocyte)
CSF3R colony stimulating factor 3 receptor (granulocyte)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNTT DNA nucleotidylexotransferase
EIF4B eukaryotic translation initiation factor 4B
EMD emerin
EZR ezrin
FHOD1 formin homology 2 domain containing 1
FLT3LG fms-related tyrosine kinase 3 ligand
FOXP3 forkhead box P3
GBA glucosidase, beta, acid
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GTDC1 glycosyltransferase-like domain containing 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HAVCR2 hepatitis A virus cellular receptor 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMOX1 heme oxygenase 1
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGH immunoglobulin heavy locus
IL10 interleukin 10
IL2 interleukin 2
IL27 interleukin 27
IL5 interleukin 5
IL6 interleukin 6
IRF3 interferon regulatory factor 3
JAK2 Janus kinase 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KLC3 kinesin light chain 3
KLF3 Kruppel-like factor 3 (basic)
LINS lines homolog (Drosophila)
MEST mesoderm specific transcript
MPL MPL proto-oncogene, thrombopoietin receptor
MRC1 mannose receptor, C type 1
MYD88 myeloid differentiation primary response 88
NOS3 nitric oxide synthase 3 (endothelial cell)
NR5A1 nuclear receptor subfamily 5, group A, member 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PDCD1 programmed cell death 1
PRNP prion protein
PRSS33 protease, serine, 33
RAB43 RAB43, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RIPK2 receptor-interacting serine-threonine kinase 2
RPSA ribosomal protein SA
SIRPA signal-regulatory protein alpha
SLC44A2 solute carrier family 44 (choline transporter), member 2
STAB2 stabilin 2
SYK spleen tyrosine kinase
TFRC transferrin receptor
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TLX1 T-cell leukemia homeobox 1
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TPSD1 tryptase delta 1
TRAF3 TNF receptor-associated factor 3
TTYH2 tweety family member 2
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C