sprouting angiogenesis Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The extension of new blood vessels from existing capillaries into avascular tissues resulting from the proliferation of blood vessel endothelial cells. (Gene Ontology, GO_0002040)
External Link http://amigo.geneontology.org/amigo/term/GO:0002040
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Genes

59 genes participating in the sprouting angiogenesis biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
ADGRA2 adhesion G protein-coupled receptor A2
ADTRP androgen-dependent TFPI-regulating protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
BMP4 bone morphogenetic protein 4
BMPER BMP binding endothelial regulator
CCBE1 collagen and calcium binding EGF domains 1
CDH13 cadherin 13
CDH5 cadherin 5, type 2 (vascular endothelium)
CRIPTO3 cripto, EGF-CFC family member 3
CTNND1 catenin (cadherin-associated protein), delta 1
DLL1 delta-like 1 (Drosophila)
E2F7 E2F transcription factor 7
E2F8 E2F transcription factor 8
EFNB2 ephrin-B2
EGR3 early growth response 3
EHD4 EH-domain containing 4
ENG endoglin
EPHB4 EPH receptor B4
ESM1 endothelial cell-specific molecule 1
FGF13 fibroblast growth factor 13
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GREM1 gremlin 1, DAN family BMP antagonist
ITGB1BP1 integrin beta 1 binding protein 1
JMJD6 jumonji domain containing 6
KDR kinase insert domain receptor
LOXL2 lysyl oxidase-like 2
MIA3 melanoma inhibitory activity family, member 3
MICALL1 MICAL-like 1
NAXE NAD(P)HX epimerase
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRARP NOTCH-regulated ankyrin repeat protein
NRP1 neuropilin 1
OTULIN OTU deubiquitinase with linear linkage specificity
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PARVA parvin, alpha
PGF placental growth factor
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PTK2B protein tyrosine kinase 2 beta
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RNF213 ring finger protein 213
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RSPO3 R-spondin 3
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLIT2 slit homolog 2 (Drosophila)
SRF serum response factor (c-fos serum response element-binding transcription factor)
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VEGFD vascular endothelial growth factor D
YJEFN3 YjeF N-terminal domain containing 3