srf_17591768_igmpos_igdpos_b_cells_lof_mouse_gpl339_gds2805 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2805
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Genes

140 genes differentially expressed following the srf_17591768_igmpos_igdpos_b_cells_lof_mouse_gpl339_gds2805 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
GJB5 gap junction protein, beta 5, 31.1kDa 0.178526
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.178129
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 0.166951
FOXO4 forkhead box O4 0.163967
TRAPPC4 trafficking protein particle complex 4 0.159926
PRPF31 pre-mRNA processing factor 31 0.15844
ANKRD28 ankyrin repeat domain 28 0.156109
RAB33B RAB33B, member RAS oncogene family 0.148913
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.148362
SLURP1 secreted LY6/PLAUR domain containing 1 0.148016
TUFM Tu translation elongation factor, mitochondrial 0.145351
CLCC1 chloride channel CLIC-like 1 0.144531
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.13139
CDCA3 cell division cycle associated 3 0.125356
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 0.125356
PLSCR3 phospholipid scramblase 3 0.119001
TOP1MT topoisomerase (DNA) I, mitochondrial 0.116351
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.107871
AHCTF1 AT hook containing transcription factor 1 0.103209
EXOSC1 exosome component 1 0.097488
OR2H2 olfactory receptor, family 2, subfamily H, member 2 0.096512
TERF2IP telomeric repeat binding factor 2, interacting protein 0.079855
EPHA3 EPH receptor A3 0.078918
BPIFB1 BPI fold containing family B, member 1 0.078688
LRP2 low density lipoprotein receptor-related protein 2 0.07528
BHLHA15 basic helix-loop-helix family, member a15 0.073177
ZCCHC3 zinc finger, CCHC domain containing 3 0.072384
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.071128
STBD1 starch binding domain 1 0.066816
KRT8 keratin 8, type II 0.064652
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) 0.05996
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.057518
TINAG tubulointerstitial nephritis antigen 0.048879
PCYOX1 prenylcysteine oxidase 1 0.048452
MDFIC MyoD family inhibitor domain containing 0.040836
SPRR3 small proline-rich protein 3 0.036183
CEP57L1 centrosomal protein 57kDa-like 1 0.034753
GSTO1 glutathione S-transferase omega 1 0.03037
HLA-A major histocompatibility complex, class I, A 0.02787
TBC1D23 TBC1 domain family, member 23 0.025733
RESP18 regulated endocrine-specific protein 18 0.023922
FAM102A family with sequence similarity 102, member A 0.022052
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.017555
MAP2K5 mitogen-activated protein kinase kinase 5 0.014823
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.011277
SETD4 SET domain containing 4 0.010938
NAP1L4 nucleosome assembly protein 1-like 4 0.008581
KIAA1191 KIAA1191 0.007363
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.003742
KANSL1L KAT8 regulatory NSL complex subunit 1-like 0.002928
ABHD17C abhydrolase domain containing 17C 3.04E-4

decreased expression

Symbol Name Standardized Value
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -1.27117
EPHA8 EPH receptor A8 -1.17699
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -1.16991
GATAD1 GATA zinc finger domain containing 1 -1.15811
RBPMS RNA binding protein with multiple splicing -1.14349
WWC1 WW and C2 domain containing 1 -1.13309
SYNJ2 synaptojanin 2 -1.081
SOCS3 suppressor of cytokine signaling 3 -1.07971
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -1.03822
GCC2 GRIP and coiled-coil domain containing 2 -1.02266
PREB prolactin regulatory element binding -1.017
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -0.976247
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.96114
NRBP1 nuclear receptor binding protein 1 -0.952092
HHIP hedgehog interacting protein -0.939896
DZIP1 DAZ interacting zinc finger protein 1 -0.925288
MEPCE methylphosphate capping enzyme -0.910929
RAB14 RAB14, member RAS oncogene family -0.892122
ANO10 anoctamin 10 -0.887029
CLEC1B C-type lectin domain family 1, member B -0.884802
CLGN calmegin -0.860101
HIRA histone cell cycle regulator -0.856053
TCP11 t-complex 11, testis-specific -0.813443
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.810414
RAD54L RAD54-like (S. cerevisiae) -0.796939
MARCKS myristoylated alanine-rich protein kinase C substrate -0.770132
CUX1 cut-like homeobox 1 -0.768516
HAPLN1 hyaluronan and proteoglycan link protein 1 -0.767443
MIOX myo-inositol oxygenase -0.759161
GSPT1 G1 to S phase transition 1 -0.744692
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -0.740168
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 -0.720357
PGD phosphogluconate dehydrogenase -0.692766
YPEL1 yippee-like 1 (Drosophila) -0.689967
SDCCAG3 serologically defined colon cancer antigen 3 -0.689446
STAG2 stromal antigen 2 -0.688555
MAPK10 mitogen-activated protein kinase 10 -0.675684
EVI5 ecotropic viral integration site 5 -0.666937
SERAC1 serine active site containing 1 -0.666692
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -0.660393
C1R complement component 1, r subcomponent -0.655841
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -0.653213
TUBGCP4 tubulin, gamma complex associated protein 4 -0.652617
ANXA6 annexin A6 -0.648531
PTMA prothymosin, alpha -0.646325
PASK PAS domain containing serine/threonine kinase -0.631893
MAP7 microtubule-associated protein 7 -0.624872
EHD1 EH-domain containing 1 -0.611408
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -0.606443
MYO5B myosin VB -0.600791
DCAF11 DDB1 and CUL4 associated factor 11 -0.58271
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.582112
NCL nucleolin -0.574001
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 -0.573191
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 -0.566855
PTH1R parathyroid hormone 1 receptor -0.556567
IL36RN interleukin 36 receptor antagonist -0.550251
CTSE cathepsin E -0.532443
TRABD TraB domain containing -0.531026
PDLIM5 PDZ and LIM domain 5 -0.530441
OLA1 Obg-like ATPase 1 -0.519836
NECAP2 NECAP endocytosis associated 2 -0.497499
RPL18 ribosomal protein L18 -0.490817
CNN2 calponin 2 -0.490387
IER3IP1 immediate early response 3 interacting protein 1 -0.48914
FBXO22 F-box protein 22 -0.484909
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -0.481123
BET1L Bet1 golgi vesicular membrane trafficking protein-like -0.472722
OAZ2 ornithine decarboxylase antizyme 2 -0.469756
SDC2 syndecan 2 -0.460764
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.459941
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.457834
NRK Nik related kinase -0.444695
TOB2 transducer of ERBB2, 2 -0.441633
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -0.439537
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.438631
HLTF helicase-like transcription factor -0.074893
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.071633
POLG polymerase (DNA directed), gamma -0.062809
MRPL19 mitochondrial ribosomal protein L19 -0.05919
SIPA1L2 signal-induced proliferation-associated 1 like 2 -0.052082
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 -0.049876
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -0.045194
ZDHHC14 zinc finger, DHHC-type containing 14 -0.029268
EHBP1L1 EH domain binding protein 1-like 1 -0.024712
TRAF3 TNF receptor-associated factor 3 -0.024495
ABHD12 abhydrolase domain containing 12 -0.015895
MTF1 metal-regulatory transcription factor 1 -0.005543
DCAF8 DDB1 and CUL4 associated factor 8 -8.6E-5
Funding