stachydrine-2743 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the stachydrine-2743 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM8 ADAM metallopeptidase domain 8
ADCY3 adenylate cyclase 3
AGGF1 angiogenic factor with G patch and FHA domains 1
ANKRD12 ankyrin repeat domain 12
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APP amyloid beta (A4) precursor protein
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
B9D2 B9 protein domain 2
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BIN1 bridging integrator 1
BMP1 bone morphogenetic protein 1
C14ORF93 chromosome 14 open reading frame 93
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMTA2 calmodulin binding transcription activator 2
CEP76 centrosomal protein 76kDa
CGA glycoprotein hormones, alpha polypeptide
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLIP4 CAP-GLY domain containing linker protein family, member 4
COL1A2 collagen, type I, alpha 2
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ERCC1 excision repair cross-complementation group 1
FCMR Fc fragment of IgM receptor
FH fumarate hydratase
FHL1 four and a half LIM domains 1
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GYG2 glycogenin 2
HCRP1 hepatocellular carcinoma-related HCRP1
HOMER3 homer scaffolding protein 3
HOXB5 homeobox B5
HYAL1 hyaluronoglucosaminidase 1
IDS iduronate 2-sulfatase
IL11 interleukin 11
KAT6A K(lysine) acetyltransferase 6A
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM5A lysine (K)-specific demethylase 5A
KLHL23 kelch-like family member 23
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT10 keratin 10, type I
LEPR leptin receptor
LRRC14 leucine rich repeat containing 14
MED23 mediator complex subunit 23
MEF2D myocyte enhancer factor 2D
METTL16 methyltransferase like 16
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP11 matrix metallopeptidase 11
MTG1 mitochondrial ribosome-associated GTPase 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEU3 sialidase 3 (membrane sialidase)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRTN neurturin
OSBPL10 oxysterol binding protein-like 10
PAQR3 progestin and adipoQ receptor family member III
PER3 period circadian clock 3
PLA2G12A phospholipase A2, group XIIA
PLK3 polo-like kinase 3
PLLP plasmolipin
PMP22 peripheral myelin protein 22
POLQ polymerase (DNA directed), theta
POMT2 protein-O-mannosyltransferase 2
PRF1 perforin 1 (pore forming protein)
RAB40C RAB40C, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RGS10 regulator of G-protein signaling 10
RIOK3 RIO kinase 3
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RWDD3 RWD domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SCHIP1 schwannomin interacting protein 1
SDF4 stromal cell derived factor 4
SH2B1 SH2B adaptor protein 1
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SIRT5 sirtuin 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLPI secretory leukocyte peptidase inhibitor
SOAT1 sterol O-acyltransferase 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STC1 stanniocalcin 1
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
TBKBP1 TBK1 binding protein 1
TK1 thymidine kinase 1, soluble
TUBA4B tubulin, alpha 4b
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USB1 U6 snRNA biogenesis 1
XYLT1 xylosyltransferase I
YIPF2 Yip1 domain family, member 2
ZNF202 zinc finger protein 202
ZNF226 zinc finger protein 226
ZNF518A zinc finger protein 518A
ZNF74 zinc finger protein 74

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ALS2CL ALS2 C-terminal like
APOLD1 apolipoprotein L domain containing 1
ARPIN actin-related protein 2/3 complex inhibitor
AUTS2 autism susceptibility candidate 2
BMP15 bone morphogenetic protein 15
BST2 bone marrow stromal cell antigen 2
BTF3P12 basic transcription factor 3 pseudogene 12
C8ORF60 chromosome 8 open reading frame 60
CD34 CD34 molecule
CD83 CD83 molecule
CFAP45 cilia and flagella associated protein 45
CLCN2 chloride channel, voltage-sensitive 2
CNR2 cannabinoid receptor 2 (macrophage)
CORT cortistatin
CST6 cystatin E/M
DCAF4 DDB1 and CUL4 associated factor 4
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLK2 delta-like 2 homolog (Drosophila)
DNALI1 dynein, axonemal, light intermediate chain 1
EDAR ectodysplasin A receptor
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
FAM212B family with sequence similarity 212, member B
FXYD5 FXYD domain containing ion transport regulator 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GLB1L galactosidase, beta 1-like
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR27 G protein-coupled receptor 27
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H2BJ histone cluster 1, H2bj
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
IL12RB1 interleukin 12 receptor, beta 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JMJD4 jumonji domain containing 4
KDM8 lysine (K)-specific demethylase 8
KEL Kell blood group, metallo-endopeptidase
KIAA0894 KIAA0894 protein
LARP6 La ribonucleoprotein domain family, member 6
LRRC20 leucine rich repeat containing 20
MFSD12 major facilitator superfamily domain containing 12
MMP15 matrix metallopeptidase 15 (membrane-inserted)
NECAB3 N-terminal EF-hand calcium binding protein 3
NIPAL2 NIPA-like domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPFFR1 neuropeptide FF receptor 1
NPTX2 neuronal pentraxin II
NTF3 neurotrophin 3
ONECUT2 one cut homeobox 2
OSMR oncostatin M receptor
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PDE8B phosphodiesterase 8B
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCD1 phospholipase C, delta 1
PMEL premelanosome protein
POLH polymerase (DNA directed), eta
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVRL3 poliovirus receptor-related 3
RAB8B RAB8B, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPAP2 RNA polymerase II associated protein 2
RPL34 ribosomal protein L34
RPS15A ribosomal protein S15a
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP7 SUMO1/sentrin specific peptidase 7
SERGEF secretion regulating guanine nucleotide exchange factor
SLC12A8 solute carrier family 12, member 8
SMA4 glucuronidase, beta pseudogene
SPINK4 serine peptidase inhibitor, Kazal type 4
STX1A syntaxin 1A (brain)
TCP10 t-complex 10
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TICAM1 toll-like receptor adaptor molecule 1
TLR5 toll-like receptor 5
TM4SF4 transmembrane 4 L six family member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TYRP1 tyrosinase-related protein 1
VEGFC vascular endothelial growth factor C
XAB2 XPA binding protein 2
ZNF16 zinc finger protein 16