| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the stachydrine-2743 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADCY3 | adenylate cyclase 3 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| APP | amyloid beta (A4) precursor protein |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| B9D2 | B9 protein domain 2 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BIN1 | bridging integrator 1 |
| BMP1 | bone morphogenetic protein 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CEP76 | centrosomal protein 76kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COL1A2 | collagen, type I, alpha 2 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| ERCC1 | excision repair cross-complementation group 1 |
| FCMR | Fc fragment of IgM receptor |
| FH | fumarate hydratase |
| FHL1 | four and a half LIM domains 1 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GYG2 | glycogenin 2 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HOMER3 | homer scaffolding protein 3 |
| HOXB5 | homeobox B5 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IDS | iduronate 2-sulfatase |
| IL11 | interleukin 11 |
| KAT6A | K(lysine) acetyltransferase 6A |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLHL23 | kelch-like family member 23 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT10 | keratin 10, type I |
| LEPR | leptin receptor |
| LRRC14 | leucine rich repeat containing 14 |
| MED23 | mediator complex subunit 23 |
| MEF2D | myocyte enhancer factor 2D |
| METTL16 | methyltransferase like 16 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP11 | matrix metallopeptidase 11 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRTN | neurturin |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PER3 | period circadian clock 3 |
| PLA2G12A | phospholipase A2, group XIIA |
| PLK3 | polo-like kinase 3 |
| PLLP | plasmolipin |
| PMP22 | peripheral myelin protein 22 |
| POLQ | polymerase (DNA directed), theta |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRF1 | perforin 1 (pore forming protein) |
| RAB40C | RAB40C, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RGS10 | regulator of G-protein signaling 10 |
| RIOK3 | RIO kinase 3 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RWDD3 | RWD domain containing 3 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCHIP1 | schwannomin interacting protein 1 |
| SDF4 | stromal cell derived factor 4 |
| SH2B1 | SH2B adaptor protein 1 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SIRT5 | sirtuin 5 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SOAT1 | sterol O-acyltransferase 1 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STC1 | stanniocalcin 1 |
| STK17B | serine/threonine kinase 17b |
| STK4 | serine/threonine kinase 4 |
| TBKBP1 | TBK1 binding protein 1 |
| TK1 | thymidine kinase 1, soluble |
| TUBA4B | tubulin, alpha 4b |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| USB1 | U6 snRNA biogenesis 1 |
| XYLT1 | xylosyltransferase I |
| YIPF2 | Yip1 domain family, member 2 |
| ZNF202 | zinc finger protein 202 |
| ZNF226 | zinc finger protein 226 |
| ZNF518A | zinc finger protein 518A |
| ZNF74 | zinc finger protein 74 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ALS2CL | ALS2 C-terminal like |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| AUTS2 | autism susceptibility candidate 2 |
| BMP15 | bone morphogenetic protein 15 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CD34 | CD34 molecule |
| CD83 | CD83 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORT | cortistatin |
| CST6 | cystatin E/M |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| EDAR | ectodysplasin A receptor |
| EFNA3 | ephrin-A3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM212B | family with sequence similarity 212, member B |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GLB1L | galactosidase, beta 1-like |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR27 | G protein-coupled receptor 27 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIRA | histone cell cycle regulator |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| JMJD4 | jumonji domain containing 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA0894 | KIAA0894 protein |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LRRC20 | leucine rich repeat containing 20 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX2 | neuronal pentraxin II |
| NTF3 | neurotrophin 3 |
| ONECUT2 | one cut homeobox 2 |
| OSMR | oncostatin M receptor |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PDE8B | phosphodiesterase 8B |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCD1 | phospholipase C, delta 1 |
| PMEL | premelanosome protein |
| POLH | polymerase (DNA directed), eta |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB8B | RAB8B, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL34 | ribosomal protein L34 |
| RPS15A | ribosomal protein S15a |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC12A8 | solute carrier family 12, member 8 |
| SMA4 | glucuronidase, beta pseudogene |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STX1A | syntaxin 1A (brain) |
| TCP10 | t-complex 10 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR5 | toll-like receptor 5 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TYRP1 | tyrosinase-related protein 1 |
| VEGFC | vascular endothelial growth factor C |
| XAB2 | XPA binding protein 2 |
| ZNF16 | zinc finger protein 16 |