stachydrine-4469 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the stachydrine-4469 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALOX12 arachidonate 12-lipoxygenase
AMPD3 adenosine monophosphate deaminase 3
ARHGAP4 Rho GTPase activating protein 4
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BTNL3 butyrophilin-like 3
C1ORF61 chromosome 1 open reading frame 61
CA5B carbonic anhydrase VB, mitochondrial
CD68 CD68 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHN2 chimerin 2
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CRHR2 corticotropin releasing hormone receptor 2
CTNS cystinosin, lysosomal cystine transporter
DCHS2 dachsous cadherin-related 2
DMP1 dentin matrix acidic phosphoprotein 1
ECE1 endothelin converting enzyme 1
EDNRA endothelin receptor type A
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPS8L3 EPS8-like 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBXL18 F-box and leucine-rich repeat protein 18
FGF18 fibroblast growth factor 18
FGF6 fibroblast growth factor 6
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT1 fms-related tyrosine kinase 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GVINP1 GTPase, very large interferon inducible pseudogene 1
HMHB1 histocompatibility (minor) HB-1
HOXD11 homeobox D11
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IGHM immunoglobulin heavy constant mu
IL16 interleukin 16
IL36RN interleukin 36 receptor antagonist
IL6R interleukin 6 receptor
ITGA7 integrin, alpha 7
KCNIP1 Kv channel interacting protein 1
KCTD14 potassium channel tetramerization domain containing 14
KIAA0319 KIAA0319
KIAA0509 uncharacterized LOC57242
LEFTY1 left-right determination factor 1
LINC00312 long intergenic non-protein coding RNA 312
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC48 leucine rich repeat containing 48
LTC4S leukotriene C4 synthase
MAK male germ cell-associated kinase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NRP2 neuropilin 2
NUDCD3 NudC domain containing 3
OLFML2B olfactomedin-like 2B
OPRM1 opioid receptor, mu 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PHOX2B paired-like homeobox 2b
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCH pro-melanin-concentrating hormone
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PRDM1 PR domain containing 1, with ZNF domain
PRDX2 peroxiredoxin 2
PRMT8 protein arginine methyltransferase 8
PRPH2 peripherin 2 (retinal degeneration, slow)
PRR5L proline rich 5 like
PRUNE2 prune homolog 2 (Drosophila)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RANBP3 RAN binding protein 3
RBM48 RNA binding motif protein 48
REEP2 receptor accessory protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS3 regulator of G-protein signaling 3
RIMS2 regulating synaptic membrane exocytosis 2
RUNX1 runt-related transcription factor 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SORT1 sortilin 1
SPATA6 spermatogenesis associated 6
SRRT serrate, RNA effector molecule
STAB1 stabilin 1
SYCP2 synaptonemal complex protein 2
TEF thyrotrophic embryonic factor
TIMP3 TIMP metallopeptidase inhibitor 3
USP29 ubiquitin specific peptidase 29
VIPR2 vasoactive intestinal peptide receptor 2
VPS9D1 VPS9 domain containing 1
WDR78 WD repeat domain 78
YIPF4 Yip1 domain family, member 4
ZHX3 zinc fingers and homeoboxes 3
ZNF528 zinc finger protein 528
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACVR2B activin A receptor, type IIB
AK5 adenylate kinase 5
APOLD1 apolipoprotein L domain containing 1
ASB7 ankyrin repeat and SOCS box containing 7
ATP13A2 ATPase type 13A2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BICC1 BicC family RNA binding protein 1
C4ORF29 chromosome 4 open reading frame 29
CALCOCO1 calcium binding and coiled-coil domain 1
CARD8 caspase recruitment domain family, member 8
CCDC9 coiled-coil domain containing 9
CENPJ centromere protein J
CEP295 centrosomal protein 295kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLSPN claspin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTNAP3B contactin associated protein-like 3B
COBL cordon-bleu WH2 repeat protein
COLGALT2 collagen beta(1-O)galactosyltransferase 2
DCAF13 DDB1 and CUL4 associated factor 13
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGF epidermal growth factor
ELP6 elongator acetyltransferase complex subunit 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO46 F-box protein 46
FBXW12 F-box and WD repeat domain containing 12
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GPATCH3 G patch domain containing 3
GRAMD4 GRAM domain containing 4
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IL17RB interleukin 17 receptor B
IRAK4 interleukin-1 receptor-associated kinase 4
KDM4D lysine (K)-specific demethylase 4D
KIAA0754 KIAA0754
KPNA5 karyopherin alpha 5 (importin alpha 6)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LIN37 lin-37 DREAM MuvB core complex component
LRRC37A3 leucine rich repeat containing 37, member A3
MFSD11 major facilitator superfamily domain containing 11
MGC12488
MTMR6 myotubularin related protein 6
MVP major vault protein
MX1 MX dynamin-like GTPase 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NME5 NME/NM23 family member 5
NPY1R neuropeptide Y receptor Y1
PDE12 phosphodiesterase 12
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLXNA3 plexin A3
PLXNB3 plexin B3
POM121 POM121 transmembrane nucleoporin
RAB33B RAB33B, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RPGR retinitis pigmentosa GTPase regulator
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SELL selectin L
SIX1 SIX homeobox 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNHG3 small nucleolar RNA host gene 3
SOX12 SRY (sex determining region Y)-box 12
SPAG16 sperm associated antigen 16
SREBF1 sterol regulatory element binding transcription factor 1
TH tyrosine hydroxylase
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSC22D4 TSC22 domain family, member 4
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3C tubulin, alpha 3c
ULK1 unc-51 like autophagy activating kinase 1
USB1 U6 snRNA biogenesis 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB39 zinc finger and BTB domain containing 39
ZC3H12A zinc finger CCCH-type containing 12A
ZFHX3 zinc finger homeobox 3
ZNF112 zinc finger protein 112
ZNF286A zinc finger protein 286A
ZNF350 zinc finger protein 350
ZNF573 zinc finger protein 573
ZNF606 zinc finger protein 606
ZNF721 zinc finger protein 721
ZNF76 zinc finger protein 76