star Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description steroidogenic acute regulatory protein|The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6770)
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Genes

44 genes co-occuring with the biological term star in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AFG3L2 AFG3-like AAA ATPase 2
AKAP1 A kinase (PRKA) anchor protein 1
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
BMP15 bone morphogenetic protein 15
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
CCHCR1 coiled-coil alpha-helical rod protein 1
CCNL2 cyclin L2
CDK10 cyclin-dependent kinase 10
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
EGFR epidermal growth factor receptor
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXL2 forkhead box L2
GDF9 growth differentiation factor 9
HCRT hypocretin (orexin) neuropeptide precursor
HCRTR1 hypocretin (orexin) receptor 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
INHBA inhibin, beta A
INSR insulin receptor
JAK2 Janus kinase 2
JUN jun proto-oncogene
LEP leptin
LONP1 lon peptidase 1, mitochondrial
LONP2 lon peptidase 2, peroxisomal
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MIR27A microRNA 27a
MRAP melanocortin 2 receptor accessory protein
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
STAR steroidogenic acute regulatory protein
STARD3 StAR-related lipid transfer (START) domain containing 3
TNF tumor necrosis factor
UBE2I ubiquitin-conjugating enzyme E2I
USF2 upstream transcription factor 2, c-fos interacting
VDAC1 voltage-dependent anion channel 1