steroid biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. (Gene Ontology, GO_0006694)
External Link http://amigo.geneontology.org/amigo/term/GO_0006694
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Genes

51 genes participating in the steroid biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACOT8 acyl-CoA thioesterase 8
ACOX2 acyl-CoA oxidase 2, branched chain
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
AKR1D1 aldo-keto reductase family 1, member D1
AMACR alpha-methylacyl-CoA racemase
BAAT bile acid CoA:amino acid N-acyltransferase
CH25H cholesterol 25-hydroxylase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
FAXDC2 fatty acid hydroxylase domain containing 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDXR ferredoxin reductase
GUCY2C guanylate cyclase 2C
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MSMO1 methylsterol monooxygenase 1
OSBP oxysterol binding protein
OSBPL1A oxysterol binding protein-like 1A
OSBPL2 oxysterol binding protein-like 2
OSBPL3 oxysterol binding protein-like 3
OSBPL6 oxysterol binding protein-like 6
OSBPL7 oxysterol binding protein-like 7
OSBPL9 oxysterol binding protein-like 9
PMVK phosphomevalonate kinase
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRLR prolactin receptor
RDH8 retinol dehydrogenase 8 (all-trans)
SCP2 sterol carrier protein 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SQLE squalene epoxidase
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)