steroid biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. (Gene Ontology, GO_0006694)
External Link http://amigo.geneontology.org/amigo/term/GO:0006694
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Genes

26 genes participating in the steroid biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
CD163L1 CD163 molecule-like 1
CH25H cholesterol 25-hydroxylase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHRS11 dehydrogenase/reductase (SDR family) member 11
FAXDC2 fatty acid hydroxylase domain containing 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDXR ferredoxin reductase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
LMBR1 limb development membrane protein 1
MSMO1 methylsterol monooxygenase 1
PMVK phosphomevalonate kinase
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRLR prolactin receptor
RDH8 retinol dehydrogenase 8 (all-trans)
SQLE squalene epoxidase
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SYCP2 synaptonemal complex protein 2