steroid Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from triterpenoids. (Chemical Entities of Biological Interest Ontology, CHEBI_35341)
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Genes

223 genes co-occuring with the biological term steroid in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACE angiotensin I converting enzyme
ACPP acid phosphatase, prostate
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR2 adiponectin receptor 2
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1D1 aldo-keto reductase family 1, member D1
ALAS1 5'-aminolevulinate synthase 1
AMH anti-Mullerian hormone
AR androgen receptor
ARID1A AT rich interactive domain 1A (SWI-like)
AZIN2 antizyme inhibitor 2
BAG1 BCL2-associated athanogene
BCL2 B-cell CLL/lymphoma 2
BRCA1 breast cancer 1, early onset
C4B complement component 4B (Chido blood group)
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL11 chemokine (C-C motif) ligand 11
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCNE1 cyclin E1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLU clusterin
COMT catechol-O-methyltransferase
CTCF CCCTC-binding factor (zinc finger protein)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DGKQ diacylglycerol kinase, theta 110kDa
DICER1 dicer 1, ribonuclease type III
EMP2 epithelial membrane protein 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FASN fatty acid synthase
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FDX1 ferredoxin 1
FKBP4 FK506 binding protein 4, 59kDa
FKBPL FK506 binding protein like
FLG filaggrin
FLII flightless I homolog (Drosophila)
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXA1 forkhead box A1
FSHR follicle stimulating hormone receptor
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
GHRL ghrelin/obestatin prepropeptide
GLUL glutamate-ammonia ligase
GNLY granulysin
GSTA2 glutathione S-transferase alpha 2
GSTA3 glutathione S-transferase alpha 3
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HP haptoglobin
HPSE heparanase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGHE immunoglobulin heavy constant epsilon
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1RN interleukin 1 receptor antagonist
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL5 interleukin 5
INSIG1 insulin induced gene 1
IRF1 interferon regulatory factor 1
KANK2 KN motif and ankyrin repeat domains 2
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK3 kallikrein-related peptidase 3
KRT5 keratin 5, type II
LCN2 lipocalin 2
LEP leptin
LHCGR luteinizing hormone/choriogonadotropin receptor
LIN28A lin-28 homolog A (C. elegans)
LVRN laeverin
MAP2 microtubule-associated protein 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MB myoglobin
MEIS1 Meis homeobox 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP9 matrix metallopeptidase 9
MT1A metallothionein 1A
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR5A1 nuclear receptor subfamily 5, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
PAEP progestagen-associated endometrial protein
PELP1 proline, glutamate and leucine rich protein 1
PGR progesterone receptor
PGRMC1 progesterone receptor membrane component 1
PLAU plasminogen activator, urokinase
PLCE1 phospholipase C, epsilon 1
PLXNB1 plexin B1
POR P450 (cytochrome) oxidoreductase
POSTN periostin, osteoblast specific factor
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRLR prolactin receptor
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTHLH parathyroid hormone-like hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRU protein tyrosine phosphatase, receptor type, U
RANBP9 RAN binding protein 9
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RGN regucalcin
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
SCARB1 scavenger receptor class B, member 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCN5A sodium channel, voltage gated, type V alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SDC3 syndecan 3
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SFTPD surfactant protein D
SHBG sex hormone-binding globulin
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SOD2 superoxide dismutase 2, mitochondrial
SRA1 steroid receptor RNA activator 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SRD5A3 steroid 5 alpha-reductase 3
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIP1 stress-induced phosphoprotein 1
STS steroid sulfatase (microsomal), isozyme S
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SYNPO synaptopodin
TAC3 tachykinin 3
TARBP2 TAR (HIV-1) RNA binding protein 2
TBX21 T-box 21
TDG thymine-DNA glycosylase
TERT telomerase reverse transcriptase
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNXB tenascin XB
TP53 tumor protein p53
TRERF1 transcriptional regulating factor 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TTLL5 tubulin tyrosine ligase-like family member 5
U2AF2 U2 small nuclear RNA auxiliary factor 2
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNT3A wingless-type MMTV integration site family, member 3A
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
ZDHHC21 zinc finger, DHHC-type containing 21
ZDHHC7 zinc finger, DHHC-type containing 7