stk11 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description serine/threonine kinase 11|This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6794)
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Genes

7 genes co-occuring with the biological term stk11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CHEK2 checkpoint kinase 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
PALB2 partner and localizer of BRCA2
PTEN phosphatase and tensin homolog
STK11 serine/threonine kinase 11
TP53 tumor protein p53
TUSC3 tumor suppressor candidate 3