strabismus Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

229 genes co-occuring with the disease strabismus in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
KIF21A kinesin family member 21A 2.31121
PHOX2A paired-like homeobox 2a 2.11097
CHN1 chimerin 1 1.89777
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.72547
VANGL2 VANGL planar cell polarity protein 2 1.66916
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.58939
HOXA1 homeobox A1 1.54054
VANGL1 VANGL planar cell polarity protein 1 1.51633
SALL4 spalt-like transcription factor 4 1.35768
CLVS1 clavesin 1 1.30751
NKD2 naked cuticle homolog 2 (Drosophila) 1.25645
FRMD7 FERM domain containing 7 1.2495
FZD6 frizzled class receptor 6 1.20266
PRICKLE2 prickle homolog 2 (Drosophila) 1.19575
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) 1.17679
PRELID1 PRELI domain containing 1 1.17507
NKD1 naked cuticle homolog 1 (Drosophila) 1.10973
EBP emopamil binding protein (sterol isomerase) 1.08873
WNT11 wingless-type MMTV integration site family, member 11 1.07068
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.0627
DDT D-dopachrome tautomerase 1.03409
ADAL adenosine deaminase-like 1.00161
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.986849
ADGRG1 adhesion G protein-coupled receptor G1 0.9696
OR2B2 olfactory receptor, family 2, subfamily B, member 2 0.966663
AMTN amelotin 0.956196
DPT dermatopontin 0.9238
PTCH1 patched 1 0.885569
ANKRD6 ankyrin repeat domain 6 0.86018
CASQ2 calsequestrin 2 (cardiac muscle) 0.856905
GLRB glycine receptor, beta 0.846669
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 0.842573
ZC3H13 zinc finger CCCH-type containing 13 0.836017
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 0.835198
FUS FUS RNA binding protein 0.819616
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.796232
SURF1 surfeit 1 0.773296
SCRIB scribbled planar cell polarity protein 0.766351
FMN1 formin 1 0.756156
PPT1 palmitoyl-protein thioesterase 1 0.756156
NLK nemo-like kinase 0.752085
FGF13 fibroblast growth factor 13 0.751271
DUSP22 dual specificity phosphatase 22 0.748424
BMP2K BMP2 inducible kinase 0.74436
DAAM2 dishevelled associated activator of morphogenesis 2 0.743547
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.743141
UBE2A ubiquitin-conjugating enzyme E2A 0.734622
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 0.725311
ECEL1 endothelin converting enzyme-like 1 0.722077
PDLIM1 PDZ and LIM domain 1 0.717232
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 0.712392
EFNB1 ephrin-B1 0.709169
PMM2 phosphomannomutase 2 0.70233
FOXF2 forkhead box F2 0.699116
DSE dermatan sulfate epimerase 0.698715
PRICKLE1 prickle homolog 1 (Drosophila) 0.697911
FOXC2 forkhead box C2 0.682693
WDFY2 WD repeat and FYVE domain containing 2 0.671925
CHD7 chromodomain helicase DNA binding protein 7 0.670732
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.669538
RAB2A RAB2A, member RAS oncogene family 0.659611
FZD3 frizzled class receptor 3 0.658818
HOXB1 homeobox B1 0.650903
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.649323
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.643797
MBD5 methyl-CpG binding domain protein 5 0.63907
FGF17 fibroblast growth factor 17 0.636315
DAAM1 dishevelled associated activator of morphogenesis 1 0.635921
CRLF1 cytokine receptor-like factor 1 0.630813
FOXQ1 forkhead box Q1 0.623359
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.616703
COPA coatomer protein complex, subunit alpha 0.616703
NBPF1 neuroblastoma breakpoint family, member 1 0.604981
FOXL2 forkhead box L2 0.583163
WNT5B wingless-type MMTV integration site family, member 5B 0.582384
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.577716
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.576161
DVL3 dishevelled segment polarity protein 3 0.573828
EVC2 Ellis van Creveld syndrome 2 0.568386
CCDC27 coiled-coil domain containing 27 0.561392
AMBN ameloblastin (enamel matrix protein) 0.55712
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.547032
RAB2B RAB2B, member RAS oncogene family 0.533088
OSTM1 osteopetrosis associated transmembrane protein 1 0.532314
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.531154
PCDH11Y protocadherin 11 Y-linked 0.528449
COL9A1 collagen, type IX, alpha 1 0.526132
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.522273
MTM1 myotubularin 1 0.518805
NMS neuromedin S 0.508808
WNT5A wingless-type MMTV integration site family, member 5A 0.507273
DVL2 dishevelled segment polarity protein 2 0.504207
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.499997
HES4 hes family bHLH transcription factor 4 0.499997
WNT3 wingless-type MMTV integration site family, member 3 0.49274
PRKCZ protein kinase C, zeta 0.489311
PCDH11X protocadherin 11 X-linked 0.483224
LSR lipolysis stimulated lipoprotein receptor 0.47753
DLG1 discs, large homolog 1 (Drosophila) 0.477151
MCM8 minichromosome maintenance complex component 8 0.466172
TBCE tubulin folding cofactor E 0.445052
SDCBP syndecan binding protein (syntenin) 0.443923
OSCAR osteoclast associated, immunoglobulin-like receptor 0.437906
CLCN7 chloride channel, voltage-sensitive 7 0.436402
ZIC2 Zic family member 2 0.435651
RORA RAR-related orphan receptor A 0.434148
LARS leucyl-tRNA synthetase 0.430017
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.429266
EVC Ellis van Creveld protein 0.422515
NUMA1 nuclear mitotic apparatus protein 1 0.421765
GADD45G growth arrest and DNA-damage-inducible, gamma 0.416896
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 0.407545
PEX19 peroxisomal biogenesis factor 19 0.404184
SETX senataxin 0.398216
CUL1 cullin 1 0.395235
FYB FYN binding protein 0.392629
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.387794
CPSF3L cleavage and polyadenylation specific factor 3-like 0.384822
OMG oligodendrocyte myelin glycoprotein 0.380368
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.378514
MYDGF myeloid-derived growth factor 0.377402
PTK7 protein tyrosine kinase 7 (inactive) 0.377031
DVL1 dishevelled segment polarity protein 1 0.365932
HTN3 histatin 3 0.363716
FBLIM1 filamin binding LIM protein 1 0.363716
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.360395
NR2E3 nuclear receptor subfamily 2, group E, member 3 0.356341
CYCS cytochrome c, somatic 0.355604
YARS tyrosyl-tRNA synthetase 0.354868
VSX1 visual system homeobox 1 0.354868
JMJD6 jumonji domain containing 6 0.35082
CA8 carbonic anhydrase VIII 0.347511
STAT2 signal transducer and activator of transcription 2, 113kDa 0.338707
COL11A1 collagen, type XI, alpha 1 0.337975
PAX6 paired box 6 0.337608
IFITM2 interferon induced transmembrane protein 2 0.334315
EREG epiregulin 0.33066
NOTCH1 notch 1 0.328105
FZD4 frizzled class receptor 4 0.32701
TTPA tocopherol (alpha) transfer protein 0.322637
PANK2 pantothenate kinase 2 0.321545
ENAM enamelin 0.32009
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.316092
MAP2K4 mitogen-activated protein kinase kinase 4 0.315366
HEXA hexosaminidase A (alpha polypeptide) 0.311377
CLCN1 chloride channel, voltage-sensitive 1 0.307757
SIX3 SIX homeobox 3 0.30631
GREM2 gremlin 2, DAN family BMP antagonist 0.305587
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.293334
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.285802
CNTN2 contactin 2 (axonal) 0.285802
GK glycerol kinase 0.280439
EFNB2 ephrin-B2 0.280082
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.272241
BTC betacellulin 0.269753
PER1 period circadian clock 1 0.266913
HNF4A hepatocyte nuclear factor 4, alpha 0.26266
TYRP1 tyrosinase-related protein 1 0.249257
FOXC1 forkhead box C1 0.241196
NCSTN nicastrin 0.240847
UBE2S ubiquitin-conjugating enzyme E2S 0.233183
EP300 E1A binding protein p300 0.230063
AXIN1 axin 1 0.218715
PITX2 paired-like homeodomain 2 0.217352
GLO1 glyoxalase I 0.215314
FGF8 fibroblast growth factor 8 (androgen-induced) 0.214636
PRSS21 protease, serine, 21 (testisin) 0.214297
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.214297
FN1 fibronectin 1 0.210253
UBE2K ubiquitin-conjugating enzyme E2K 0.195501
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.193915
CXCR5 chemokine (C-X-C motif) receptor 5 0.175146
TBP TATA box binding protein 0.173571
LAX1 lymphocyte transmembrane adaptor 1 0.172291
HEXB hexosaminidase B (beta polypeptide) 0.165217
WNT3A wingless-type MMTV integration site family, member 3A 0.162109
IDS iduronate 2-sulfatase 0.162109
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.161523
FUT2 fucosyltransferase 2 (secretor status included) 0.160574
FGF19 fibroblast growth factor 19 0.160574
PRL prolactin 0.132215
BSG basigin (Ok blood group) 0.131573
FGFR3 fibroblast growth factor receptor 3 0.124737
F3 coagulation factor III (thromboplastin, tissue factor) 0.120281
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.115512
CADM1 cell adhesion molecule 1 0.1141
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.112337
PIDD1 p53-induced death domain protein 1 0.111805
HCRT hypocretin (orexin) neuropeptide precursor 0.111787
MBP myelin basic protein 0.110263
TPH1 tryptophan hydroxylase 1 0.109751
FGFR2 fibroblast growth factor receptor 2 0.108215
AQP4 aquaporin 4 0.099402
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.099017
TTR transthyretin 0.097719
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.097645
PLAT plasminogen activator, tissue 0.096543
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.095602
PSEN1 presenilin 1 0.092675
AXL AXL receptor tyrosine kinase 0.09079
LRP2 low density lipoprotein receptor-related protein 2 0.090102
PTER phosphotriesterase related 0.090019
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.089909
MNX1 motor neuron and pancreas homeobox 1 0.08894
IFNB1 interferon, beta 1, fibroblast 0.088688
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.088156
DMPK dystrophia myotonica-protein kinase 0.088072
TF transferrin 0.08796
CREBBP CREB binding protein 0.087365
AREG amphiregulin 0.087309
NF1 neurofibromin 1 0.085997
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.085247
COL2A1 collagen, type II, alpha 1 0.085218
PKD1P6 polycystic kidney disease 1 (autosomal dominant) pseudogene 6 0.084786
FOXP2 forkhead box P2 0.084727
ERBB4 erb-b2 receptor tyrosine kinase 4 0.081994
BCHE butyrylcholinesterase 0.081668
ATXN3 ataxin 3 0.080441
F12 coagulation factor XII (Hageman factor) 0.079143
DNM2 dynamin 2 0.078263
CA2 carbonic anhydrase II 0.077927
ACAN aggrecan 0.077866
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.076488
FGF1 fibroblast growth factor 1 (acidic) 0.074976
OXA1L oxidase (cytochrome c) assembly 1-like 0.074511
SUMO2 small ubiquitin-like modifier 2 0.073704
ASPH aspartate beta-hydroxylase 0.073016
PPARA peroxisome proliferator-activated receptor alpha 0.072985
CXCL12 chemokine (C-X-C motif) ligand 12 0.070384