streptomycin-1578 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the streptomycin-1578 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
AIM2 absent in melanoma 2
AMBRA1 autophagy/beclin-1 regulator 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG12 autophagy related 12
BATF basic leucine zipper transcription factor, ATF-like
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCL7A B-cell CLL/lymphoma 7A
BCL7C B-cell CLL/lymphoma 7C
BEGAIN brain-enriched guanylate kinase-associated
C9ORF156 chromosome 9 open reading frame 156
CANT1 calcium activated nucleotidase 1
CCNT1 cyclin T1
CDC42 cell division cycle 42
CDK5 cyclin-dependent kinase 5
CENPI centromere protein I
CLEC11A C-type lectin domain family 11, member A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTN1 contactin 1
COPS8 COP9 signalosome subunit 8
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DEAF1 DEAF1 transcription factor
DUSP2 dual specificity phosphatase 2
DUSP3 dual specificity phosphatase 3
ENO3 enolase 3 (beta, muscle)
FAM214B family with sequence similarity 214, member B
FN1 fibronectin 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GEMIN6 gem (nuclear organelle) associated protein 6
GNB5 guanine nucleotide binding protein (G protein), beta 5
GOLIM4 golgi integral membrane protein 4
GRK5 G protein-coupled receptor kinase 5
GUSBP3 glucuronidase, beta pseudogene 3
HAUS5 HAUS augmin-like complex, subunit 5
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HTATSF1 HIV-1 Tat specific factor 1
HYI hydroxypyruvate isomerase (putative)
IGFBP7 insulin-like growth factor binding protein 7
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM5A lysine (K)-specific demethylase 5A
KIZ kizuna centrosomal protein
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00339 long intergenic non-protein coding RNA 339
LRRC23 leucine rich repeat containing 23
MAP2K7 mitogen-activated protein kinase kinase 7
MDC1 mediator of DNA-damage checkpoint 1
MED1 mediator complex subunit 1
MMP25 matrix metallopeptidase 25
MYO1C myosin IC
N4BP1 NEDD4 binding protein 1
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NOL12 nucleolar protein 12
NRBP1 nuclear receptor binding protein 1
NRGN neurogranin (protein kinase C substrate, RC3)
NUP205 nucleoporin 205kDa
OSBPL2 oxysterol binding protein-like 2
OVGP1 oviductal glycoprotein 1, 120kDa
PALM paralemmin
PCGF2 polycomb group ring finger 2
PKNOX1 PBX/knotted 1 homeobox 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLG polymerase (DNA directed), gamma
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PRKX protein kinase, X-linked
RBM19 RNA binding motif protein 19
RECQL4 RecQ protein-like 4
RPS11 ribosomal protein S11
SAG S-antigen; retina and pineal gland (arrestin)
SAMD9 sterile alpha motif domain containing 9
SBNO1 strawberry notch homolog 1 (Drosophila)
SDC2 syndecan 2
SECISBP2L SECIS binding protein 2-like
SH3BP2 SH3-domain binding protein 2
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SMAD6 SMAD family member 6
SMG5 SMG5 nonsense mediated mRNA decay factor
SOCS3 suppressor of cytokine signaling 3
SP140L SP140 nuclear body protein-like
SPDEF SAM pointed domain containing ETS transcription factor
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TGIF2 TGFB-induced factor homeobox 2
TM2D1 TM2 domain containing 1
TNK1 tyrosine kinase, non-receptor, 1
TRA T cell receptor alpha locus
TRMT61A tRNA methyltransferase 61A
TTC31 tetratricopeptide repeat domain 31
USP2 ubiquitin specific peptidase 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
ZNF318 zinc finger protein 318
ZNF350 zinc finger protein 350
ZNF408 zinc finger protein 408
ZNF444 zinc finger protein 444

decreased expression

Symbol Name
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
AMPD2 adenosine monophosphate deaminase 2
AMT aminomethyltransferase
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD40 ankyrin repeat domain 40
ASB13 ankyrin repeat and SOCS box containing 13
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AZI2 5-azacytidine induced 2
C12ORF43 chromosome 12 open reading frame 43
C19ORF54 chromosome 19 open reading frame 54
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CAPG capping protein (actin filament), gelsolin-like
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CD82 CD82 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEND1 cell cycle exit and neuronal differentiation 1
CEP170B centrosomal protein 170B
CEP85 centrosomal protein 85kDa
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLTCL1 clathrin, heavy chain-like 1
CSK c-src tyrosine kinase
CSRNP2 cysteine-serine-rich nuclear protein 2
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DIXDC1 DIX domain containing 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPF2 D4, zinc and double PHD fingers family 2
DSN1 DSN1, MIS12 kinetochore complex component
ECI1 enoyl-CoA delta isomerase 1
EPM2AIP1 EPM2A (laforin) interacting protein 1
EXOSC10 exosome component 10
FAM50B family with sequence similarity 50, member B
FBXL14 F-box and leucine-rich repeat protein 14
FBXL6 F-box and leucine-rich repeat protein 6
FCHSD2 FCH and double SH3 domains 2
FURIN furin (paired basic amino acid cleaving enzyme)
GSTCD glutathione S-transferase, C-terminal domain containing
GSTM1 glutathione S-transferase mu 1
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HINFP histone H4 transcription factor
IFNA17 interferon, alpha 17
KIF15 kinesin family member 15
KIF1BP KIF1 binding protein
LBR lamin B receptor
LRRC37A2 leucine rich repeat containing 37, member A2
LYPLA2P1 lysophospholipase II pseudogene 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK10 mitogen-activated protein kinase 10
MAVS mitochondrial antiviral signaling protein
MBIP MAP3K12 binding inhibitory protein 1
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCRS1 microspherule protein 1
MGAM maltase-glucoamylase
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO19 myosin XIX
NEK11 NIMA-related kinase 11
NSD1 nuclear receptor binding SET domain protein 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PODNL1 podocan-like 1
PREPL prolyl endopeptidase-like
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PTCD1 pentatricopeptide repeat domain 1
PTGES2 prostaglandin E synthase 2
RBM41 RNA binding motif protein 41
RFPL3 ret finger protein-like 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
RPIA ribose 5-phosphate isomerase A
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RSF1 remodeling and spacing factor 1
SFMBT1 Scm-like with four mbt domains 1
SLN sarcolipin
SNX6 sorting nexin 6
SUN2 Sad1 and UNC84 domain containing 2
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TIAM2 T-cell lymphoma invasion and metastasis 2
TIPIN TIMELESS interacting protein
TMEM11 transmembrane protein 11
TMEM50B transmembrane protein 50B
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSPAN32 tetraspanin 32
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
UBXN2B UBX domain protein 2B
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
WRN Werner syndrome, RecQ helicase-like
ZNF189 zinc finger protein 189
ZNF768 zinc finger protein 768
ZNF770 zinc finger protein 770