| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the streptomycin-1578 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| AIM2 | absent in melanoma 2 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATG12 | autophagy related 12 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BCL7A | B-cell CLL/lymphoma 7A |
| BCL7C | B-cell CLL/lymphoma 7C |
| BEGAIN | brain-enriched guanylate kinase-associated |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CANT1 | calcium activated nucleotidase 1 |
| CCNT1 | cyclin T1 |
| CDC42 | cell division cycle 42 |
| CDK5 | cyclin-dependent kinase 5 |
| CENPI | centromere protein I |
| CLEC11A | C-type lectin domain family 11, member A |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CNTN1 | contactin 1 |
| COPS8 | COP9 signalosome subunit 8 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| DEAF1 | DEAF1 transcription factor |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP3 | dual specificity phosphatase 3 |
| ENO3 | enolase 3 (beta, muscle) |
| FAM214B | family with sequence similarity 214, member B |
| FN1 | fibronectin 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GOLIM4 | golgi integral membrane protein 4 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HDAC7 | histone deacetylase 7 |
| HIRA | histone cell cycle regulator |
| HTATSF1 | HIV-1 Tat specific factor 1 |
| HYI | hydroxypyruvate isomerase (putative) |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIZ | kizuna centrosomal protein |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRRC23 | leucine rich repeat containing 23 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MED1 | mediator complex subunit 1 |
| MMP25 | matrix metallopeptidase 25 |
| MYO1C | myosin IC |
| N4BP1 | NEDD4 binding protein 1 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) |
| NOL12 | nucleolar protein 12 |
| NRBP1 | nuclear receptor binding protein 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUP205 | nucleoporin 205kDa |
| OSBPL2 | oxysterol binding protein-like 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PALM | paralemmin |
| PCGF2 | polycomb group ring finger 2 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POLG | polymerase (DNA directed), gamma |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) |
| PRKX | protein kinase, X-linked |
| RBM19 | RNA binding motif protein 19 |
| RECQL4 | RecQ protein-like 4 |
| RPS11 | ribosomal protein S11 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAMD9 | sterile alpha motif domain containing 9 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SDC2 | syndecan 2 |
| SECISBP2L | SECIS binding protein 2-like |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SMAD6 | SMAD family member 6 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SOCS3 | suppressor of cytokine signaling 3 |
| SP140L | SP140 nuclear body protein-like |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TGIF2 | TGFB-induced factor homeobox 2 |
| TM2D1 | TM2 domain containing 1 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRA | T cell receptor alpha locus |
| TRMT61A | tRNA methyltransferase 61A |
| TTC31 | tetratricopeptide repeat domain 31 |
| USP2 | ubiquitin specific peptidase 2 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZNF318 | zinc finger protein 318 |
| ZNF350 | zinc finger protein 350 |
| ZNF408 | zinc finger protein 408 |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| AMPD2 | adenosine monophosphate deaminase 2 |
| AMT | aminomethyltransferase |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKRD40 | ankyrin repeat domain 40 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| AZI2 | 5-azacytidine induced 2 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CD82 | CD82 molecule |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CEP170B | centrosomal protein 170B |
| CEP85 | centrosomal protein 85kDa |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CSK | c-src tyrosine kinase |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DIXDC1 | DIX domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| ECI1 | enoyl-CoA delta isomerase 1 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| EXOSC10 | exosome component 10 |
| FAM50B | family with sequence similarity 50, member B |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTM1 | glutathione S-transferase mu 1 |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HINFP | histone H4 transcription factor |
| IFNA17 | interferon, alpha 17 |
| KIF15 | kinesin family member 15 |
| KIF1BP | KIF1 binding protein |
| LBR | lamin B receptor |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAVS | mitochondrial antiviral signaling protein |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| MCRS1 | microspherule protein 1 |
| MGAM | maltase-glucoamylase |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO19 | myosin XIX |
| NEK11 | NIMA-related kinase 11 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PODNL1 | podocan-like 1 |
| PREPL | prolyl endopeptidase-like |
| PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTGES2 | prostaglandin E synthase 2 |
| RBM41 | RNA binding motif protein 41 |
| RFPL3 | ret finger protein-like 3 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPIA | ribose 5-phosphate isomerase A |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| RSF1 | remodeling and spacing factor 1 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SLN | sarcolipin |
| SNX6 | sorting nexin 6 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TIPIN | TIMELESS interacting protein |
| TMEM11 | transmembrane protein 11 |
| TMEM50B | transmembrane protein 50B |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSPAN32 | tetraspanin 32 |
| TUBA3C | tubulin, alpha 3c |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBQLN4 | ubiquilin 4 |
| UBXN2B | UBX domain protein 2B |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| WRN | Werner syndrome, RecQ helicase-like |
| ZNF189 | zinc finger protein 189 |
| ZNF768 | zinc finger protein 768 |
| ZNF770 | zinc finger protein 770 |