streptomycin-3195 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the streptomycin-3195 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADGRL3 adhesion G protein-coupled receptor L3
AFF1 AF4/FMR2 family, member 1
ALCAM activated leukocyte cell adhesion molecule
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOB aldolase B, fructose-bisphosphate
APAF1 apoptotic peptidase activating factor 1
APOLD1 apolipoprotein L domain containing 1
AREG amphiregulin
ARTN artemin
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BNC2 basonuclin 2
C3ORF18 chromosome 3 open reading frame 18
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CD52 CD52 molecule
CLCA1 chloride channel accessory 1
CLCA2 chloride channel accessory 2
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNTNAP2 contactin associated protein-like 2
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR3 chemokine (C-X-C motif) receptor 3
DCBLD2 discoidin, CUB and LCCL domain containing 2
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DTNA dystrobrevin, alpha
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F5 E2F transcription factor 5, p130-binding
EDA ectodysplasin A
EDNRA endothelin receptor type A
EFR3B EFR3 homolog B (S. cerevisiae)
EPS8L1 EPS8-like 1
FBXL7 F-box and leucine-rich repeat protein 7
FGF22 fibroblast growth factor 22
FKBP10 FK506 binding protein 10, 65 kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FRMD4B FERM domain containing 4B
FSCN1 fascin actin-bundling protein 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GIF gastric intrinsic factor (vitamin B synthesis)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR15 G protein-coupled receptor 15
GRM3 glutamate receptor, metabotropic 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAND1 heart and neural crest derivatives expressed 1
HFE hemochromatosis
HIST1H1T histone cluster 1, H1t
HIST1H2AK histone cluster 1, H2ak
ICAM1 intercellular adhesion molecule 1
IL18RAP interleukin 18 receptor accessory protein
IL1R1 interleukin 1 receptor, type I
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KLHL20 kelch-like family member 20
KLK13 kallikrein-related peptidase 13
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMF2 lipase maturation factor 2
MATN3 matrilin 3
MC5R melanocortin 5 receptor
MCTP2 multiple C2 domains, transmembrane 2
MEG3 maternally expressed 3 (non-protein coding)
MYBPH myosin binding protein H
MYT1L myelin transcription factor 1-like
NKX2-5 NK2 homeobox 5
NPFFR1 neuropeptide FF receptor 1
NRL neural retina leucine zipper
NUP214 nucleoporin 214kDa
OGDHL oxoglutarate dehydrogenase-like
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCDH11Y protocadherin 11 Y-linked
PCDH17 protocadherin 17
PLA2G5 phospholipase A2, group V
PRB1 proline-rich protein BstNI subfamily 1
PRDM2 PR domain containing 2, with ZNF domain
PRSS53 protease, serine, 53
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHOBTB2 Rho-related BTB domain containing 2
RPL35A ribosomal protein L35a
SC5D sterol-C5-desaturase
SCN11A sodium channel, voltage gated, type XI alpha subunit
SERHL2 serine hydrolase-like 2
SIK3 SIK family kinase 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMAD1 SMAD family member 1
SMR3A submaxillary gland androgen regulated protein 3A
SNAP25 synaptosomal-associated protein, 25kDa
SPON1 spondin 1, extracellular matrix protein
SPTA1 spectrin, alpha, erythrocytic 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
THAP9 THAP domain containing 9
TRBC1 T cell receptor beta constant 1
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBR2 ubiquitin protein ligase E3 component n-recognin 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
AHDC1 AT hook, DNA binding motif, containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AOC2 amine oxidase, copper containing 2 (retina-specific)
APOD apolipoprotein D
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMC6 armadillo repeat containing 6
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
C14ORF93 chromosome 14 open reading frame 93
CAPN5 calpain 5
CD82 CD82 molecule
CHRM3 cholinergic receptor, muscarinic 3
CHST10 carbohydrate sulfotransferase 10
CIC capicua transcriptional repressor
CLCN6 chloride channel, voltage-sensitive 6
CRYGC crystallin, gamma C
CSF1R colony stimulating factor 1 receptor
CST6 cystatin E/M
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGFL7 EGF-like-domain, multiple 7
EMID1 EMI domain containing 1
FBXL2 F-box and leucine-rich repeat protein 2
FGF4 fibroblast growth factor 4
GAMT guanidinoacetate N-methyltransferase
GPX1 glutathione peroxidase 1
GRB7 growth factor receptor-bound protein 7
GYS1 glycogen synthase 1 (muscle)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC5 homeobox C5
HOXC8 homeobox C8
IFI35 interferon-induced protein 35
IL4R interleukin 4 receptor
INHA inhibin, alpha
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM5C lysine (K)-specific demethylase 5C
KIAA1456 KIAA1456
LAMB3 laminin, beta 3
LATS1 large tumor suppressor kinase 1
LDHB lactate dehydrogenase B
LMO2 LIM domain only 2 (rhombotin-like 1)
LPAR4 lysophosphatidic acid receptor 4
LYRM9 LYR motif containing 9
LYZ lysozyme
LZTR1 leucine-zipper-like transcription regulator 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MT1H metallothionein 1H
MYL5 myosin, light chain 5, regulatory
NDOR1 NADPH dependent diflavin oxidoreductase 1
ONECUT2 one cut homeobox 2
OVGP1 oviductal glycoprotein 1, 120kDa
PARD6A par-6 family cell polarity regulator alpha
PCDHA5 protocadherin alpha 5
POLL polymerase (DNA directed), lambda
PPT2 palmitoyl-protein thioesterase 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUNDC3B RUN domain containing 3B
S100A4 S100 calcium binding protein A4
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC46A3 solute carrier family 46, member 3
SOX3 SRY (sex determining region Y)-box 3
SRD5A3 steroid 5 alpha-reductase 3
SRGN serglycin
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCP10 t-complex 10
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM209 transmembrane protein 209
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
WDR62 WD repeat domain 62
WNT10B wingless-type MMTV integration site family, member 10B
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB25 zinc finger and BTB domain containing 25
ZNF137P zinc finger protein 137, pseudogene
ZNF16 zinc finger protein 16
ZNF34 zinc finger protein 34
ZNF770 zinc finger protein 770
ZNF816 zinc finger protein 816