| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the streptomycin-3195 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADGRL3 | adhesion G protein-coupled receptor L3 |
| AFF1 | AF4/FMR2 family, member 1 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| AREG | amphiregulin |
| ARTN | artemin |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BNC2 | basonuclin 2 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CASQ1 | calsequestrin 1 (fast-twitch, skeletal muscle) |
| CD52 | CD52 molecule |
| CLCA1 | chloride channel accessory 1 |
| CLCA2 | chloride channel accessory 2 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNTNAP2 | contactin associated protein-like 2 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DLGAP2 | discs, large (Drosophila) homolog-associated protein 2 |
| DTNA | dystrobrevin, alpha |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EDA | ectodysplasin A |
| EDNRA | endothelin receptor type A |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EPS8L1 | EPS8-like 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF22 | fibroblast growth factor 22 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FRMD4B | FERM domain containing 4B |
| FSCN1 | fascin actin-bundling protein 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR15 | G protein-coupled receptor 15 |
| GRM3 | glutamate receptor, metabotropic 3 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HFE | hemochromatosis |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AK | histone cluster 1, H2ak |
| ICAM1 | intercellular adhesion molecule 1 |
| IL18RAP | interleukin 18 receptor accessory protein |
| IL1R1 | interleukin 1 receptor, type I |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCNAB3 | potassium channel, voltage gated subfamily A regulatory beta subunit 3 |
| KLHL20 | kelch-like family member 20 |
| KLK13 | kallikrein-related peptidase 13 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMF2 | lipase maturation factor 2 |
| MATN3 | matrilin 3 |
| MC5R | melanocortin 5 receptor |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MYBPH | myosin binding protein H |
| MYT1L | myelin transcription factor 1-like |
| NKX2-5 | NK2 homeobox 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRL | neural retina leucine zipper |
| NUP214 | nucleoporin 214kDa |
| OGDHL | oxoglutarate dehydrogenase-like |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PCDH11Y | protocadherin 11 Y-linked |
| PCDH17 | protocadherin 17 |
| PLA2G5 | phospholipase A2, group V |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRSS53 | protease, serine, 53 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPL35A | ribosomal protein L35a |
| SC5D | sterol-C5-desaturase |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SERHL2 | serine hydrolase-like 2 |
| SIK3 | SIK family kinase 3 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD1 | SMAD family member 1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTA1 | spectrin, alpha, erythrocytic 1 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| THAP9 | THAP domain containing 9 |
| TRBC1 | T cell receptor beta constant 1 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| APOD | apolipoprotein D |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARMC6 | armadillo repeat containing 6 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAPN5 | calpain 5 |
| CD82 | CD82 molecule |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIC | capicua transcriptional repressor |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CRYGC | crystallin, gamma C |
| CSF1R | colony stimulating factor 1 receptor |
| CST6 | cystatin E/M |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGFL7 | EGF-like-domain, multiple 7 |
| EMID1 | EMI domain containing 1 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGF4 | fibroblast growth factor 4 |
| GAMT | guanidinoacetate N-methyltransferase |
| GPX1 | glutathione peroxidase 1 |
| GRB7 | growth factor receptor-bound protein 7 |
| GYS1 | glycogen synthase 1 (muscle) |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC5 | homeobox C5 |
| HOXC8 | homeobox C8 |
| IFI35 | interferon-induced protein 35 |
| IL4R | interleukin 4 receptor |
| INHA | inhibin, alpha |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1456 | KIAA1456 |
| LAMB3 | laminin, beta 3 |
| LATS1 | large tumor suppressor kinase 1 |
| LDHB | lactate dehydrogenase B |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LYRM9 | LYR motif containing 9 |
| LYZ | lysozyme |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCC | mutated in colorectal cancers |
| MT1H | metallothionein 1H |
| MYL5 | myosin, light chain 5, regulatory |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| ONECUT2 | one cut homeobox 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCDHA5 | protocadherin alpha 5 |
| POLL | polymerase (DNA directed), lambda |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUNDC3B | RUN domain containing 3B |
| S100A4 | S100 calcium binding protein A4 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDC3 | syndecan 3 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC46A3 | solute carrier family 46, member 3 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRGN | serglycin |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAOK1 | TAO kinase 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCP10 | t-complex 10 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM209 | transmembrane protein 209 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| WDR62 | WD repeat domain 62 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF16 | zinc finger protein 16 |
| ZNF34 | zinc finger protein 34 |
| ZNF770 | zinc finger protein 770 |
| ZNF816 | zinc finger protein 816 |