streptomycin-5837 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the streptomycin-5837 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANAPC5 anaphase promoting complex subunit 5
BCAS3 breast carcinoma amplified sequence 3
C21ORF2 chromosome 21 open reading frame 2
C7ORF69 chromosome 7 open reading frame 69
CA5BP1 carbonic anhydrase VB pseudogene 1
CDON cell adhesion associated, oncogene regulated
CDRT1 CMT1A duplicated region transcript 1
CEMIP cell migration inducing protein, hyaluronan binding
CNOT8 CCR4-NOT transcription complex, subunit 8
COL14A1 collagen, type XIV, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPN2 carboxypeptidase N, polypeptide 2
CSPP1 centrosome and spindle pole associated protein 1
CTSF cathepsin F
CYHR1 cysteine/histidine-rich 1
DCAF8 DDB1 and CUL4 associated factor 8
DNPEP aspartyl aminopeptidase
DPF3 D4, zinc and double PHD fingers, family 3
EFS embryonal Fyn-associated substrate
EML3 echinoderm microtubule associated protein like 3
EPHB2 EPH receptor B2
FBXL15 F-box and leucine-rich repeat protein 15
FGFR1 fibroblast growth factor receptor 1
FKBP8 FK506 binding protein 8, 38kDa
GABARAPL1 GABA(A) receptor-associated protein like 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLI2 GLI family zinc finger 2
HHLA3 HERV-H LTR-associating 3
HIST1H1D histone cluster 1, H1d
HOXC10 homeobox C10
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
INADL InaD-like (Drosophila)
INO80D INO80 complex subunit D
ITGB4 integrin, beta 4
ITSN2 intersectin 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KRT8P12 keratin 8 pseudogene 12
LAMA2 laminin, alpha 2
LAMC3 laminin, gamma 3
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LOC647070 uncharacterized LOC647070
MAN2A2 mannosidase, alpha, class 2A, member 2
METTL7A methyltransferase like 7A
MRPS12 mitochondrial ribosomal protein S12
MTERF4 mitochondrial transcription termination factor 4
MUC6 mucin 6, oligomeric mucus/gel-forming
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEK11 NIMA-related kinase 11
NF1 neurofibromin 1
NOX1 NADPH oxidase 1
NPTXR neuronal pentraxin receptor
NSUN6 NOP2/Sun domain family, member 6
OSBPL10 oxysterol binding protein-like 10
OSMR oncostatin M receptor
PCDHA5 protocadherin alpha 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PELO pelota homolog (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLD2 phospholipase D2
PLXDC1 plexin domain containing 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRF1 perforin 1 (pore forming protein)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
QTRT1 queuine tRNA-ribosyltransferase 1
SCN9A sodium channel, voltage gated, type IX alpha subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SMC1A structural maintenance of chromosomes 1A
SMYD2 SET and MYND domain containing 2
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SND1-IT1 SND1 intronic transcript 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SPINK5 serine peptidase inhibitor, Kazal type 5
SS18 synovial sarcoma translocation, chromosome 18
SSBP3 single stranded DNA binding protein 3
STOM stomatin
SUGP1 SURP and G patch domain containing 1
TBX1 T-box 1
TEX40 testis expressed 40
THOC5 THO complex 5
TRIM14 tripartite motif containing 14
TRIM62 tripartite motif containing 62
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZFHX3 zinc finger homeobox 3
ZNF440 zinc finger protein 440
ZNF492 zinc finger protein 492
ZNF500 zinc finger protein 500
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BOLA1 bolA family member 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
CAMTA2 calmodulin binding transcription activator 2
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPT centromere protein T
CHPF chondroitin polymerizing factor
CLCF1 cardiotrophin-like cytokine factor 1
CLDN14 claudin 14
CNTNAP3B contactin associated protein-like 3B
CPPED1 calcineurin-like phosphoesterase domain containing 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTDNEP1 CTD nuclear envelope phosphatase 1
CXCL3 chemokine (C-X-C motif) ligand 3
DDIT3 DNA-damage-inducible transcript 3
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DSPP dentin sialophosphoprotein
DUSP8 dual specificity phosphatase 8
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EAF2 ELL associated factor 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
EXOC5 exocyst complex component 5
FAF1 Fas (TNFRSF6) associated factor 1
FANCE Fanconi anemia, complementation group E
FURIN furin (paired basic amino acid cleaving enzyme)
FZD3 frizzled class receptor 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLCE glucuronic acid epimerase
GLDC glycine dehydrogenase (decarboxylating)
HIRIP3 HIRA interacting protein 3
HIST1H1T histone cluster 1, H1t
HMOX1 heme oxygenase 1
IL17RB interleukin 17 receptor B
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUNB jun B proto-oncogene
KIAA0232 KIAA0232
KIAA1549L KIAA1549-like
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MGMT O-6-methylguanine-DNA methyltransferase
MYO1D myosin ID
NHEJ1 nonhomologous end-joining factor 1
NRBP1 nuclear receptor binding protein 1
ORC2 origin recognition complex, subunit 2
PADI1 peptidyl arginine deiminase, type I
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRPH peripherin
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RABL6 RAB, member RAS oncogene family-like 6
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCEL sciellin
SCGB2A2 secretoglobin, family 2A, member 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SPAG4 sperm associated antigen 4
STEAP4 STEAP family member 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TIGD6 tigger transposable element derived 6
TMEM2 transmembrane protein 2
TMEM212 transmembrane protein 212
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3C tubulin, alpha 3c
URGCP upregulator of cell proliferation
UROS uroporphyrinogen III synthase
WDR76 WD repeat domain 76
ZFP36 ZFP36 ring finger protein
ZNF263 zinc finger protein 263
ZNF34 zinc finger protein 34
ZNF385D zinc finger protein 385D
ZNF528 zinc finger protein 528
ZNF586 zinc finger protein 586
ZNF623 zinc finger protein 623