| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the streptomycin-7194 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ADCY9 | adenylate cyclase 9 |
| AEN | apoptosis enhancing nuclease |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| APC | adenomatous polyposis coli |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| B9D2 | B9 protein domain 2 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCNO | cyclin O |
| CD44 | CD44 molecule (Indian blood group) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLEC16A | C-type lectin domain family 16, member A |
| CTNNBL1 | catenin, beta like 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYTH1 | cytohesin 1 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPN2 | epsin 2 |
| ESR1 | estrogen receptor 1 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM65A | family with sequence similarity 65, member A |
| FILIP1L | filamin A interacting protein 1-like |
| FLT4 | fms-related tyrosine kinase 4 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GOLGA1 | golgin A1 |
| HIST1H2BC | histone cluster 1, H2bc |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HOXA6 | homeobox A6 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT22 | intraflagellar transport 22 |
| INTS7 | integrator complex subunit 7 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ITGB4 | integrin, beta 4 |
| KLF6 | Kruppel-like factor 6 |
| KRT17 | keratin 17, type I |
| LHX2 | LIM homeobox 2 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC61 | leucine rich repeat containing 61 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAX | MYC associated factor X |
| MBD3 | methyl-CpG binding domain protein 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MPZL2 | myelin protein zero-like 2 |
| MVK | mevalonate kinase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NMT2 | N-myristoyltransferase 2 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHF20 | PHD finger protein 20 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PRLR | prolactin receptor |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RHOQ | ras homolog family member Q |
| RINT1 | RAD50 interactor 1 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL7 | ribosomal protein L7 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SKIL | SKI-like proto-oncogene |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SMC1A | structural maintenance of chromosomes 1A |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SP100 | SP100 nuclear antigen |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TJP3 | tight junction protein 3 |
| TMEM120B | transmembrane protein 120B |
| TMEM70 | transmembrane protein 70 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOR1AIP1 | torsin A interacting protein 1 |
| TRIM3 | tripartite motif containing 3 |
| U2SURP | U2 snRNP-associated SURP domain containing |
| WDR76 | WD repeat domain 76 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZNF468 | zinc finger protein 468 |
| Symbol | Name |
|---|---|
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| ALS2CL | ALS2 C-terminal like |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BCL9 | B-cell CLL/lymphoma 9 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CA11 | carbonic anhydrase XI |
| CCDC9 | coiled-coil domain containing 9 |
| CD82 | CD82 molecule |
| CEP131 | centrosomal protein 131kDa |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| E2F3 | E2F transcription factor 3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPHA2 | EPH receptor A2 |
| FGF23 | fibroblast growth factor 23 |
| FKBPL | FK506 binding protein like |
| FOSL1 | FOS-like antigen 1 |
| GPC3 | glypican 3 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HIST1H2AI | histone cluster 1, H2ai |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JMJD4 | jumonji domain containing 4 |
| KIAA0319L | KIAA0319-like |
| KLK5 | kallikrein-related peptidase 5 |
| KRT31 | keratin 31, type I |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAP1S | microtubule-associated protein 1S |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOSPD3 | motile sperm domain containing 3 |
| MPST | mercaptopyruvate sulfurtransferase |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MXD3 | MAX dimerization protein 3 |
| NEK11 | NIMA-related kinase 11 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHA5 | protocadherin alpha 5 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGBD5 | piggyBac transposable element derived 5 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PICK1 | protein interacting with PRKCA 1 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLA2G3 | phospholipase A2, group III |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PROL1 | proline rich, lacrimal 1 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| PYGB | phosphorylase, glycogen; brain |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RARS | arginyl-tRNA synthetase |
| RNF19B | ring finger protein 19B |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SH2D4A | SH2 domain containing 4A |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3 | stromal antigen 3 |
| STRN | striatin, calmodulin binding protein |
| TBX19 | T-box 19 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TLR5 | toll-like receptor 5 |
| TMEM104 | transmembrane protein 104 |
| TMEM183A | transmembrane protein 183A |
| TNS2 | tensin 2 |
| TOM1 | target of myb1 (chicken) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TUBA3C | tubulin, alpha 3c |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UBTD1 | ubiquitin domain containing 1 |
| USP36 | ubiquitin specific peptidase 36 |
| VPS9D1 | VPS9 domain containing 1 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| XAB2 | XPA binding protein 2 |
| ZNF180 | zinc finger protein 180 |
| ZNF219 | zinc finger protein 219 |
| ZNF282 | zinc finger protein 282 |
| ZNF432 | zinc finger protein 432 |
| ZNF701 | zinc finger protein 701 |