streptozocin-2535 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the streptozocin-2535 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AHNAK AHNAK nucleoprotein
ALDOB aldolase B, fructose-bisphosphate
APAF1 apoptotic peptidase activating factor 1
ARNT aryl hydrocarbon receptor nuclear translocator
ASPH aspartate beta-hydroxylase
AURKA aurora kinase A
BLVRA biliverdin reductase A
BMP8B bone morphogenetic protein 8b
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CARF calcium responsive transcription factor
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CCSER2 coiled-coil serine-rich protein 2
CD1E CD1e molecule
CDC14A cell division cycle 14A
CEP104 centrosomal protein 104kDa
CEP295 centrosomal protein 295kDa
CLTA clathrin, light chain A
COL15A1 collagen, type XV, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CTNNBL1 catenin, beta like 1
CUL2 cullin 2
CYHR1 cysteine/histidine-rich 1
DBR1 debranching RNA lariats 1
DIAPH2 diaphanous-related formin 2
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DST dystonin
DZIP3 DAZ interacting zinc finger protein 3
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GID4 GID complex subunit 4
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GOSR2 golgi SNAP receptor complex member 2
GPATCH4 G patch domain containing 4
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HN1L hematological and neurological expressed 1-like
HOXA10 homeobox A10
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL22 interleukin 22
IL27RA interleukin 27 receptor, alpha
IL6R interleukin 6 receptor
ING1 inhibitor of growth family, member 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KRIT1 KRIT1, ankyrin repeat containing
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LRRC8B leucine rich repeat containing 8 family, member B
LTB4R leukotriene B4 receptor
MANSC1 MANSC domain containing 1
MAP7 microtubule-associated protein 7
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MMP3 matrix metallopeptidase 3
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NF2 neurofibromin 2 (merlin)
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NRDE2 NRDE-2, necessary for RNA interference, domain containing
NUPR1 nuclear protein, transcriptional regulator, 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PGAP3 post-GPI attachment to proteins 3
PHC1 polyhomeotic homolog 1 (Drosophila)
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PORCN porcupine homolog (Drosophila)
POU2F2 POU class 2 homeobox 2
PRSS8 protease, serine, 8
PVR poliovirus receptor
PYCRL pyrroline-5-carboxylate reductase-like
RAB6A RAB6A, member RAS oncogene family
RHOD ras homolog family member D
SCGB1D1 secretoglobin, family 1D, member 1
SEC14L1 SEC14-like 1 (S. cerevisiae)
SGPL1 sphingosine-1-phosphate lyase 1
SH3BP2 SH3-domain binding protein 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SMAD3 SMAD family member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SP1 Sp1 transcription factor
SRSF1 serine/arginine-rich splicing factor 1
SUMO1 small ubiquitin-like modifier 1
TACC1 transforming, acidic coiled-coil containing protein 1
TBRG4 transforming growth factor beta regulator 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPD52 tumor protein D52
TRIM25 tripartite motif containing 25
TRIM36 tripartite motif containing 36
TSC2 tuberous sclerosis 2
TTF2 transcription termination factor, RNA polymerase II
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WDR76 WD repeat domain 76
ZBTB17 zinc finger and BTB domain containing 17
ZBTB7A zinc finger and BTB domain containing 7A
ZER1 zyg-11 related, cell cycle regulator
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACPP acid phosphatase, prostate
ADAM2 ADAM metallopeptidase domain 2
ADGRB1 adhesion G protein-coupled receptor B1
ADGRD2 adhesion G protein-coupled receptor D2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AIRE autoimmune regulator
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ALOX12 arachidonate 12-lipoxygenase
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASB7 ankyrin repeat and SOCS box containing 7
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BMP15 bone morphogenetic protein 15
BNC2 basonuclin 2
C14ORF105 chromosome 14 open reading frame 105
C7ORF69 chromosome 7 open reading frame 69
CCDC57 coiled-coil domain containing 57
CCDC92 coiled-coil domain containing 92
CDH8 cadherin 8, type 2
COL19A1 collagen, type XIX, alpha 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DKFZP434L187 uncharacterized LOC26082
DOK3 docking protein 3
DSPP dentin sialophosphoprotein
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA3 ephrin-A3
FAM131A family with sequence similarity 131, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBRS fibrosin
FBXO40 F-box protein 40
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FLT4 fms-related tyrosine kinase 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAREM GRB2 associated, regulator of MAPK1
GEMIN8 gem (nuclear organelle) associated protein 8
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIPR gastric inhibitory polypeptide receptor
GJA1 gap junction protein, alpha 1, 43kDa
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HAMP hepcidin antimicrobial peptide
HCG4 HLA complex group 4 (non-protein coding)
HOXC8 homeobox C8
HSPB6 heat shock protein, alpha-crystallin-related, B6
HYAL4 hyaluronoglucosaminidase 4
IFNA14 interferon, alpha 14
INO80D INO80 complex subunit D
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM5C lysine (K)-specific demethylase 5C
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT81 keratin 81, type II
LAMB3 laminin, beta 3
LEFTY2 left-right determination factor 2
LOXL3 lysyl oxidase-like 3
MBNL3 muscleblind-like splicing regulator 3
MGP matrix Gla protein
MTSS1L metastasis suppressor 1-like
MYH15 myosin, heavy chain 15
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NNAT neuronatin
PBOV1 prostate and breast cancer overexpressed 1
PCDH12 protocadherin 12
PHOX2A paired-like homeobox 2a
PICK1 protein interacting with PRKCA 1
PLCD1 phospholipase C, delta 1
PODNL1 podocan-like 1
PRDM12 PR domain containing 12
PRO2964 uncharacterized protein PRO2964
PROL1 proline rich, lacrimal 1
PRSS21 protease, serine, 21 (testisin)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF122 ring finger protein 122
RNF39 ring finger protein 39
SCGB2A2 secretoglobin, family 2A, member 2
SLC16A6 solute carrier family 16, member 6
SLC35F5 solute carrier family 35, member F5
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPEF1 sperm flagellar 1
STBD1 starch binding domain 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP3 STEAP family member 3, metalloreductase
STEAP4 STEAP family member 4
TCTN2 tectonic family member 2
TESPA1 thymocyte expressed, positive selection associated 1
TMEM212 transmembrane protein 212
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNS2 tensin 2
UPK3B uroplakin 3B
VEZT vezatin, adherens junctions transmembrane protein
ZNF132 zinc finger protein 132
ZNF749 zinc finger protein 749