| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the streptozocin-2535 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AHNAK | AHNAK nucleoprotein |
| ALDOB | aldolase B, fructose-bisphosphate |
| APAF1 | apoptotic peptidase activating factor 1 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASPH | aspartate beta-hydroxylase |
| AURKA | aurora kinase A |
| BLVRA | biliverdin reductase A |
| BMP8B | bone morphogenetic protein 8b |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CARF | calcium responsive transcription factor |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD1E | CD1e molecule |
| CDC14A | cell division cycle 14A |
| CEP104 | centrosomal protein 104kDa |
| CEP295 | centrosomal protein 295kDa |
| CLTA | clathrin, light chain A |
| COL15A1 | collagen, type XV, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CTNNBL1 | catenin, beta like 1 |
| CUL2 | cullin 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| DBR1 | debranching RNA lariats 1 |
| DIAPH2 | diaphanous-related formin 2 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DST | dystonin |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GID4 | GID complex subunit 4 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPATCH4 | G patch domain containing 4 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HN1L | hematological and neurological expressed 1-like |
| HOXA10 | homeobox A10 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL22 | interleukin 22 |
| IL27RA | interleukin 27 receptor, alpha |
| IL6R | interleukin 6 receptor |
| ING1 | inhibitor of growth family, member 1 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| LTB4R | leukotriene B4 receptor |
| MANSC1 | MANSC domain containing 1 |
| MAP7 | microtubule-associated protein 7 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MMP3 | matrix metallopeptidase 3 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NF2 | neurofibromin 2 (merlin) |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PGAP3 | post-GPI attachment to proteins 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
| PORCN | porcupine homolog (Drosophila) |
| POU2F2 | POU class 2 homeobox 2 |
| PRSS8 | protease, serine, 8 |
| PVR | poliovirus receptor |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB6A | RAB6A, member RAS oncogene family |
| RHOD | ras homolog family member D |
| SCGB1D1 | secretoglobin, family 1D, member 1 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SGPL1 | sphingosine-1-phosphate lyase 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SMAD3 | SMAD family member 3 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) |
| SP1 | Sp1 transcription factor |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SUMO1 | small ubiquitin-like modifier 1 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPD52 | tumor protein D52 |
| TRIM25 | tripartite motif containing 25 |
| TRIM36 | tripartite motif containing 36 |
| TSC2 | tuberous sclerosis 2 |
| TTF2 | transcription termination factor, RNA polymerase II |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACPP | acid phosphatase, prostate |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AIRE | autoimmune regulator |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ALOX12 | arachidonate 12-lipoxygenase |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BMP15 | bone morphogenetic protein 15 |
| BNC2 | basonuclin 2 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC92 | coiled-coil domain containing 92 |
| CDH8 | cadherin 8, type 2 |
| COL19A1 | collagen, type XIX, alpha 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DKFZP434L187 | uncharacterized LOC26082 |
| DOK3 | docking protein 3 |
| DSPP | dentin sialophosphoprotein |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EFNA3 | ephrin-A3 |
| FAM131A | family with sequence similarity 131, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBRS | fibrosin |
| FBXO40 | F-box protein 40 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
| FLT4 | fms-related tyrosine kinase 4 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GIPR | gastric inhibitory polypeptide receptor |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HAMP | hepcidin antimicrobial peptide |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HOXC8 | homeobox C8 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HYAL4 | hyaluronoglucosaminidase 4 |
| IFNA14 | interferon, alpha 14 |
| INO80D | INO80 complex subunit D |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM5C | lysine (K)-specific demethylase 5C |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KRT81 | keratin 81, type II |
| LAMB3 | laminin, beta 3 |
| LEFTY2 | left-right determination factor 2 |
| LOXL3 | lysyl oxidase-like 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MGP | matrix Gla protein |
| MTSS1L | metastasis suppressor 1-like |
| MYH15 | myosin, heavy chain 15 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NNAT | neuronatin |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCDH12 | protocadherin 12 |
| PHOX2A | paired-like homeobox 2a |
| PICK1 | protein interacting with PRKCA 1 |
| PLCD1 | phospholipase C, delta 1 |
| PODNL1 | podocan-like 1 |
| PRDM12 | PR domain containing 12 |
| PRO2964 | uncharacterized protein PRO2964 |
| PROL1 | proline rich, lacrimal 1 |
| PRSS21 | protease, serine, 21 (testisin) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNF122 | ring finger protein 122 |
| RNF39 | ring finger protein 39 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SPEF1 | sperm flagellar 1 |
| STBD1 | starch binding domain 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STEAP4 | STEAP family member 4 |
| TCTN2 | tectonic family member 2 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMEM212 | transmembrane protein 212 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TNS2 | tensin 2 |
| UPK3B | uroplakin 3B |
| VEZT | vezatin, adherens junctions transmembrane protein |
| ZNF132 | zinc finger protein 132 |
| ZNF749 | zinc finger protein 749 |