streptozocin-5836 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the streptozocin-5836 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM22 ADAM metallopeptidase domain 22
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARMCX4 armadillo repeat containing, X-linked 4
BICD1 bicaudal D homolog 1 (Drosophila)
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CBX4 chromobox homolog 4
CBX8 chromobox homolog 8
CCDC93 coiled-coil domain containing 93
CDC14A cell division cycle 14A
CES2 carboxylesterase 2
CFLAR CASP8 and FADD-like apoptosis regulator
CHAT choline O-acetyltransferase
CHEK2 checkpoint kinase 2
CHMP6 charged multivesicular body protein 6
CLCN7 chloride channel, voltage-sensitive 7
CNOT8 CCR4-NOT transcription complex, subunit 8
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CORO2A coronin, actin binding protein, 2A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYHR1 cysteine/histidine-rich 1
DAAM2 dishevelled associated activator of morphogenesis 2
DSTYK dual serine/threonine and tyrosine protein kinase
EPHB2 EPH receptor B2
EVI5 ecotropic viral integration site 5
EWSR1 EWS RNA-binding protein 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM50B family with sequence similarity 50, member B
FCGRT Fc fragment of IgG, receptor, transporter, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GPSM3 G-protein signaling modulator 3
GRK5 G protein-coupled receptor kinase 5
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IPO8 importin 8
IQSEC2 IQ motif and Sec7 domain 2
ITGB5 integrin, beta 5
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KYNU kynureninase
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRRC61 leucine rich repeat containing 61
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MTM1 myotubularin 1
MYEF2 myelin expression factor 2
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL9 myosin, light chain 9, regulatory
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
PDGFB platelet-derived growth factor beta polypeptide
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLXNA3 plexin A3
PPARA peroxisome proliferator-activated receptor alpha
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSORS1C1 psoriasis susceptibility 1 candidate 1
RAB36 RAB36, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RNF146 ring finger protein 146
RPL13 ribosomal protein L13
RUNX1 runt-related transcription factor 1
RYK receptor-like tyrosine kinase
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIRT3 sirtuin 3
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMC1A structural maintenance of chromosomes 1A
SNX13 sorting nexin 13
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
TAGLN3 transgelin 3
TAPBP TAP binding protein (tapasin)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCP11L1 t-complex 11, testis-specific-like 1
TEX40 testis expressed 40
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLE3 transducin-like enhancer of split 3
TRIM14 tripartite motif containing 14
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAC14 Vac14 homolog (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
WIPF1 WAS/WASL interacting protein family, member 1
YY1 YY1 transcription factor
ZNF174 zinc finger protein 174
ZNF223 zinc finger protein 223
ZNF324 zinc finger protein 324
ZNF335 zinc finger protein 335
ZNF426 zinc finger protein 426
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ANG angiogenin, ribonuclease, RNase A family, 5
APH1B APH1B gamma secretase subunit
APLP1 amyloid beta (A4) precursor-like protein 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF80 chromosome 11 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
CAPN5 calpain 5
CBX7 chromobox homolog 7
CCDC85C coiled-coil domain containing 85C
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKL3 cyclin-dependent kinase-like 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DOCK1 dedicator of cytokinesis 1
DUSP8 dual specificity phosphatase 8
EAF2 ELL associated factor 2
EGF epidermal growth factor
EGLN2 egl-9 family hypoxia-inducible factor 2
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
F8 coagulation factor VIII, procoagulant component
FA2H fatty acid 2-hydroxylase
FAM102A family with sequence similarity 102, member A
FAM53B family with sequence similarity 53, member B
GFPT2 glutamine-fructose-6-phosphate transaminase 2
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFT54 intraflagellar transport 54
IL17RB interleukin 17 receptor B
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCTD15 potassium channel tetramerization domain containing 15
KIF16B kinesin family member 16B
KLHL36 kelch-like family member 36
LOC100127972 uncharacterized LOC100127972
LOC100286895 cell division cycle 27 homolog pseudogene
LOC730101 uncharacterized LOC730101
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRK1 leucine-rich repeat kinase 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCMBP minichromosome maintenance complex binding protein
METTL8 methyltransferase like 8
NECAB3 N-terminal EF-hand calcium binding protein 3
NECAP2 NECAP endocytosis associated 2
NHEJ1 nonhomologous end-joining factor 1
NOL12 nucleolar protein 12
NUP62CL nucleoporin 62kDa C-terminal like
OSR2 odd-skipped related transciption factor 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PADI1 peptidyl arginine deiminase, type I
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAQR6 progestin and adipoQ receptor family member VI
PARP16 poly (ADP-ribose) polymerase family, member 16
PDE8B phosphodiesterase 8B
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAC8 placenta-specific 8
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PORCN porcupine homolog (Drosophila)
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR14L proline rich 14-like
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTK6 protein tyrosine kinase 6
RHOBTB1 Rho-related BTB domain containing 1
RIC8B RIC8 guanine nucleotide exchange factor B
RNF31 ring finger protein 31
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCAMP5 secretory carrier membrane protein 5
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SOAT1 sterol O-acyltransferase 1
SOX12 SRY (sex determining region Y)-box 12
SPATA1 spermatogenesis associated 1
ST5 suppression of tumorigenicity 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX17 syntaxin 17
SYNE2 spectrin repeat containing, nuclear envelope 2
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TMEM104 transmembrane protein 104
TMEM212 transmembrane protein 212
TMEM62 transmembrane protein 62
TRABD TraB domain containing
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USP27X ubiquitin specific peptidase 27, X-linked
VEZT vezatin, adherens junctions transmembrane protein
WDR19 WD repeat domain 19
WDR37 WD repeat domain 37
XAB2 XPA binding protein 2
ZNF528 zinc finger protein 528
ZSCAN31 zinc finger and SCAN domain containing 31