| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the streptozocin-6098 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADCK2 | aarF domain containing kinase 2 |
| ADD2 | adducin 2 (beta) |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ARTN | artemin |
| AVPR1B | arginine vasopressin receptor 1B |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BIN1 | bridging integrator 1 |
| BMP1 | bone morphogenetic protein 1 |
| BST1 | bone marrow stromal cell antigen 1 |
| C2 | complement component 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC40 | coiled-coil domain containing 40 |
| CCDC64 | coiled-coil domain containing 64 |
| CCKAR | cholecystokinin A receptor |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK18 | cyclin-dependent kinase 18 |
| CERS4 | ceramide synthase 4 |
| CFHR2 | complement factor H-related 2 |
| CLCA3P | chloride channel accessory 3, pseudogene |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL7A1 | collagen, type VII, alpha 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DNASE1 | deoxyribonuclease I |
| DPP4 | dipeptidyl-peptidase 4 |
| EXPH5 | exophilin 5 |
| FBLN1 | fibulin 1 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FSTL1 | follistatin-like 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HOXA10 | homeobox A10 |
| HP | haptoglobin |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IBSP | integrin-binding sialoprotein |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLHL3 | kelch-like family member 3 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAP1A | microtubule-associated protein 1A |
| MAPK8 | mitogen-activated protein kinase 8 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MYF5 | myogenic factor 5 |
| NAV3 | neuron navigator 3 |
| NPPA | natriuretic peptide A |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCDHB6 | protocadherin beta 6 |
| PDLIM3 | PDZ and LIM domain 3 |
| PLEK | pleckstrin |
| PLXDC1 | plexin domain containing 1 |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 |
| POPDC3 | popeye domain containing 3 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRRG3 | proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| R3HDM1 | R3H domain containing 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCN1A | sodium channel, voltage gated, type I alpha subunit |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFEB | transcription factor EB |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRIB2 | tribbles pseudokinase 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBE3A | ubiquitin protein ligase E3A |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZNF154 | zinc finger protein 154 |
| ZNF442 | zinc finger protein 442 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AUTS2 | autism susceptibility candidate 2 |
| BMP15 | bone morphogenetic protein 15 |
| C5AR2 | complement component 5a receptor 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEP97 | centrosomal protein 97kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP9 | dual specificity phosphatase 9 |
| EDAR | ectodysplasin A receptor |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERCC6 | excision repair cross-complementation group 6 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FMOD | fibromodulin |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALK1 | galactokinase 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HAMP | hepcidin antimicrobial peptide |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H4D | histone cluster 1, H4d |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| ICK | intestinal cell (MAK-like) kinase |
| IFNA14 | interferon, alpha 14 |
| IFT54 | intraflagellar transport 54 |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LENEP | lens epithelial protein |
| LMTK2 | lemur tyrosine kinase 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MCC | mutated in colorectal cancers |
| METTL16 | methyltransferase like 16 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MVD | mevalonate (diphospho) decarboxylase |
| MYLK | myosin light chain kinase |
| NDE1 | nudE neurodevelopment protein 1 |
| PARPBP | PARP1 binding protein |
| PCDHA5 | protocadherin alpha 5 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PODXL2 | podocalyxin-like 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAB40C | RAB40C, member RAS oncogene family |
| RLN1 | relaxin 1 |
| RPL10L | ribosomal protein L10-like |
| S100A9 | S100 calcium binding protein A9 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPRYD7 | SPRY domain containing 7 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSBP3 | single stranded DNA binding protein 3 |
| TDRD1 | tudor domain containing 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM242 | transmembrane protein 242 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TRABD | TraB domain containing |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBG2 | tubulin, gamma 2 |
| UBQLN4 | ubiquilin 4 |
| USP19 | ubiquitin specific peptidase 19 |
| USP20 | ubiquitin specific peptidase 20 |
| WDR19 | WD repeat domain 19 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF532 | zinc finger protein 532 |
| ZNF571 | zinc finger protein 571 |
