striae distensae Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description Thinned, erythematous, depressed bands of atrophic skin. Initially, striae appear as flattened and thinned, pinkish linear regions of the skin. Striae tend to enlarge in length and become reddish or purplish. Later, striae tend to appear as white, depressed bands that are parallel to the lines of skin tension. Striae distensae occur most often in areas that have been subject to distension such as the lower back, buttocks, thighs, breast, abdomen, and shoulders. (Human Phenotype Ontology, HP_0001065)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001065
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Genes

15 genes associated with the striae distensae phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
AIP aryl hydrocarbon receptor interacting protein
COL3A1 collagen, type III, alpha 1
CUL4B cullin 4B
FBN1 fibrillin 1
GNAS GNAS complex locus
HDAC8 histone deacetylase 8
PDE11A phosphodiesterase 11A
PDE8B phosphodiesterase 8B
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
SH3BP2 SH3-domain binding protein 2
SMAD3 SMAD family member 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNXB tenascin XB