striated muscle contraction Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. (Gene Ontology, GO_0006941)
External Link http://amigo.geneontology.org/amigo/term/GO:0006941
Similar Terms
Downloads & Tools

Genes

56 genes participating in the striated muscle contraction biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CASQ2 calsequestrin 2 (cardiac muscle)
CCDC78 coiled-coil domain containing 78
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
DMD dystrophin
DTNA dystrobrevin, alpha
GAA glucosidase, alpha; acid
GRK2 G protein-coupled receptor kinase 2
JSRP1 junctional sarcoplasmic reticulum protein 1
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLHL41 kelch-like family member 41
LMOD3 leiomodin 3 (fetal)
LOC112694756 uncharaterized LOC112694756
MYBPC3 myosin binding protein C, cardiac
MYH14 myosin, heavy chain 14, non-muscle
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLK2 myosin light chain kinase 2
NANOS1 nanos homolog 1 (Drosophila)
PGAM2 phosphoglycerate mutase 2 (muscle)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PVALEF parvalbumin like EF-hand containing
RCSD1 RCSD domain containing 1
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
RYR3 ryanodine receptor 3
SCN1B sodium channel, voltage gated, type I beta subunit
SCN2B sodium channel, voltage gated, type II beta subunit
SCN3B sodium channel, voltage gated, type III beta subunit
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMPX small muscle protein, X-linked
STAC SH3 and cysteine rich domain
STAC2 SH3 and cysteine rich domain 2
STAC3 SH3 and cysteine rich domain 3
TCAP titin-cap
TNNC2 troponin C type 2 (fast)
TNNI1 troponin I type 1 (skeletal, slow)
TNNI2 troponin I type 2 (skeletal, fast)
TNNI3 troponin I type 3 (cardiac)
TNNT1 troponin T type 1 (skeletal, slow)
TNNT2 troponin T type 2 (cardiac)
TNNT3 troponin T type 3 (skeletal, fast)
TPM1 tropomyosin 1 (alpha)
TTR transthyretin