| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the strophanthidin-2525 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AREG | amphiregulin |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATF7IP | activating transcription factor 7 interacting protein |
| B9D2 | B9 protein domain 2 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTG2 | BTG family, member 2 |
| C18ORF25 | chromosome 18 open reading frame 25 |
| C3AR1 | complement component 3a receptor 1 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNT2 | cyclin T2 |
| CD83 | CD83 molecule |
| CREM | cAMP responsive element modulator |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYHR1 | cysteine/histidine-rich 1 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DUSP1 | dual specificity phosphatase 1 |
| EED | embryonic ectoderm development |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FASTKD2 | FAST kinase domains 2 |
| FCAR | Fc fragment of IgA receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| G0S2 | G0/G1 switch 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPATCH2 | G patch domain containing 2 |
| GTPBP1 | GTP binding protein 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H4C | histone cluster 1, H4c |
| HLA-F | major histocompatibility complex, class I, F |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| IER3 | immediate early response 3 |
| IL1A | interleukin 1, alpha |
| IL1B | interleukin 1, beta |
| IL1RAP | interleukin 1 receptor accessory protein |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLF10 | Kruppel-like factor 10 |
| KLHL24 | kelch-like family member 24 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MTF1 | metal-regulatory transcription factor 1 |
| NCKAP1L | NCK-associated protein 1-like |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NFYA | nuclear transcription factor Y, alpha |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NRF1 | nuclear respiratory factor 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUPL1 | nucleoporin like 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPC1 | paraspeckle component 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTX3 | pentraxin 3, long |
| RBM15 | RNA binding motif protein 15 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS2 | regulator of G-protein signaling 2 |
| RND1 | Rho family GTPase 1 |
| RNF24 | ring finger protein 24 |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| RUFY3 | RUN and FYVE domain containing 3 |
| RUNX1 | runt-related transcription factor 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SP1 | Sp1 transcription factor |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STK17B | serine/threonine kinase 17b |
| TAPBP | TAP binding protein (tapasin) |
| THBS1 | thrombospondin 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TPMT | thiopurine S-methyltransferase |
| TXNIP | thioredoxin interacting protein |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZC3H11A | zinc finger CCCH-type containing 11A |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADM | adrenomedullin |
| ANXA2P2 | annexin A2 pseudogene 2 |
| ARMC6 | armadillo repeat containing 6 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C11ORF71 | chromosome 11 open reading frame 71 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CALHM2 | calcium homeostasis modulator 2 |
| CCDC51 | coiled-coil domain containing 51 |
| CCNE2 | cyclin E2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CISH | cytokine inducible SH2-containing protein |
| COG2 | component of oligomeric golgi complex 2 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
| DOLK | dolichol kinase |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| FAM57A | family with sequence similarity 57, member A |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FANCF | Fanconi anemia, complementation group F |
| FANCL | Fanconi anemia, complementation group L |
| FHOD1 | formin homology 2 domain containing 1 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GRAMD4 | GRAM domain containing 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPA8 | heat shock 70kDa protein 8 |
| JRKL | JRK-like |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KLF11 | Kruppel-like factor 11 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LRRC14 | leucine rich repeat containing 14 |
| LXN | latexin |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MKKS | McKusick-Kaufman syndrome |
| MOCOS | molybdenum cofactor sulfurase |
| MSRB1 | methionine sulfoxide reductase B1 |
| MUTYH | mutY homolog |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAGK | N-acetylglucosamine kinase |
| NFE2 | nuclear factor, erythroid 2 |
| NLRX1 | NLR family member X1 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAAF1 | proteasomal ATPase-associated factor 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PEX12 | peroxisomal biogenesis factor 12 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLA2G12A | phospholipase A2, group XIIA |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PNMA1 | paraneoplastic Ma antigen 1 |
| POGK | pogo transposable element with KRAB domain |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| PRDM13 | PR domain containing 13 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR3 | proline rich 3 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SETD6 | SET domain containing 6 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SUOX | sulfite oxidase |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TFB1M | transcription factor B1, mitochondrial |
| TGM5 | transglutaminase 5 |
| THAP11 | THAP domain containing 11 |
| TMEM186 | transmembrane protein 186 |
| TRIM66 | tripartite motif containing 66 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| VANGL1 | VANGL planar cell polarity protein 1 |
| WDR3 | WD repeat domain 3 |
| XAB2 | XPA binding protein 2 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF16 | zinc finger protein 16 |
| ZNF248 | zinc finger protein 248 |
| ZNF302 | zinc finger protein 302 |
| ZNF32 | zinc finger protein 32 |
| ZNF33B | zinc finger protein 33B |
| ZNF571 | zinc finger protein 571 |
| ZNF573 | zinc finger protein 573 |
| ZNF7 | zinc finger protein 7 |
| ZNF83 | zinc finger protein 83 |
