| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the strophanthidin-5826 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADM | adrenomedullin |
| AMOTL2 | angiomotin like 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF3 | activating transcription factor 3 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BCL6 | B-cell CLL/lymphoma 6 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BMP2 | bone morphogenetic protein 2 |
| BTG2 | BTG family, member 2 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CCNL1 | cyclin L1 |
| CD83 | CD83 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDKN2AIP | CDKN2A interacting protein |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLDN1 | claudin 1 |
| CLK1 | CDC-like kinase 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTGF | connective tissue growth factor |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLX2 | distal-less homeobox 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EGR1 | early growth response 1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM46C | family with sequence similarity 46, member C |
| FAM53C | family with sequence similarity 53, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H4H | histone cluster 1, H4h |
| HIST3H2A | histone cluster 3, H2a |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER5 | immediate early response 5 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| JUND | jun D proto-oncogene |
| KLF2 | Kruppel-like factor 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL20 | kelch-like family member 20 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCL1 | myeloid cell leukemia 1 |
| MYLIP | myosin regulatory light chain interacting protein |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NXF1 | nuclear RNA export factor 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSPC1 | paraspeckle component 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| RSRP1 | arginine/serine-rich protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIK3 | SIK family kinase 3 |
| SIRT1 | sirtuin 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SOCS1 | suppressor of cytokine signaling 1 |
| STK17B | serine/threonine kinase 17b |
| STX3 | syntaxin 3 |
| TEX14 | testis expressed 14 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC22D1 | TSC22 domain family, member 1 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKRD46 | ankyrin repeat domain 46 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BTBD3 | BTB (POZ) domain containing 3 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C4ORF27 | chromosome 4 open reading frame 27 |
| CBR3 | carbonyl reductase 3 |
| CBX7 | chromobox homolog 7 |
| CCDC51 | coiled-coil domain containing 51 |
| CCNA2 | cyclin A2 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC7 | cell division cycle 7 |
| CDH7 | cadherin 7, type 2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| COBL | cordon-bleu WH2 repeat protein |
| CUTC | cutC copper transporter |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAIM | Fas apoptotic inhibitory molecule |
| FASTKD3 | FAST kinase domains 3 |
| FBXW2 | F-box and WD repeat domain containing 2 |
| FHOD1 | formin homology 2 domain containing 1 |
| FKBPL | FK506 binding protein like |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GID4 | GID complex subunit 4 |
| GLCE | glucuronic acid epimerase |
| GSPT2 | G1 to S phase transition 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HMG20A | high mobility group 20A |
| HMGA2 | high mobility group AT-hook 2 |
| HOXA10 | homeobox A10 |
| HOXA9 | homeobox A9 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL17RB | interleukin 17 receptor B |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JRKL | JRK-like |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0355 | KIAA0355 |
| KLF11 | Kruppel-like factor 11 |
| LMNB1 | lamin B1 |
| LOC100272216 | uncharacterized LOC100272216 |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| NIF3L1 | NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) |
| NOL12 | nucleolar protein 12 |
| NPR3 | natriuretic peptide receptor 3 |
| NSUN5P2 | NOP2/Sun domain family, member 5 pseudogene 2 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PALB2 | partner and localizer of BRCA2 |
| PCYOX1L | prenylcysteine oxidase 1 like |
| PNMA1 | paraneoplastic Ma antigen 1 |
| POGK | pogo transposable element with KRAB domain |
| POLI | polymerase (DNA directed) iota |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RGS20 | regulator of G-protein signaling 20 |
| RIN2 | Ras and Rab interactor 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RUFY2 | RUN and FYVE domain containing 2 |
| S100PBP | S100P binding protein |
| SHROOM2 | shroom family member 2 |
| SNPH | syntaphilin |
| SPATA7 | spermatogenesis associated 7 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STBD1 | starch binding domain 1 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UBAC1 | UBA domain containing 1 |
| WDR5B | WD repeat domain 5B |
| WDR91 | WD repeat domain 91 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| XPA | xeroderma pigmentosum, complementation group A |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF232 | zinc finger protein 232 |
| ZNF239 | zinc finger protein 239 |
| ZNF248 | zinc finger protein 248 |
| ZNF365 | zinc finger protein 365 |
| ZNF652 | zinc finger protein 652 |
