| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the strophanthidin-7182 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADCY6 | adenylate cyclase 6 |
| AK1 | adenylate kinase 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BLVRA | biliverdin reductase A |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CCNK | cyclin K |
| CDC14A | cell division cycle 14A |
| CEP104 | centrosomal protein 104kDa |
| CLDN9 | claudin 9 |
| COPS8 | COP9 signalosome subunit 8 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPD | carboxypeptidase D |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DAPK2 | death-associated protein kinase 2 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DRD1 | dopamine receptor D1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DXO | decapping exoribonuclease |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EMC1 | ER membrane protein complex subunit 1 |
| ESR1 | estrogen receptor 1 |
| EXOC5 | exocyst complex component 5 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| GLRX | glutaredoxin (thioltransferase) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H4F | histone cluster 1, H4f |
| HNMT | histamine N-methyltransferase |
| HOXA10 | homeobox A10 |
| IFT122 | intraflagellar transport 122 |
| IFT38 | intraflagellar transport 38 |
| ITGA6 | integrin, alpha 6 |
| KCNIP1 | Kv channel interacting protein 1 |
| KIAA0485 | uncharacterized LOC57235 |
| LACTB2 | lactamase, beta 2 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MED28 | mediator complex subunit 28 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MYO9B | myosin IXB |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCOA2 | nuclear receptor coactivator 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PAPOLA | poly(A) polymerase alpha |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDHA6 | protocadherin alpha 6 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PFDN6 | prefoldin subunit 6 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTK6 | protein tyrosine kinase 6 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PXN | paxillin |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBBP9 | retinoblastoma binding protein 9 |
| RBM34 | RNA binding motif protein 34 |
| RCAN1 | regulator of calcineurin 1 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RNASEH2B | ribonuclease H2, subunit B |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SC5D | sterol-C5-desaturase |
| SECTM1 | secreted and transmembrane 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD1B | SET domain containing 1B |
| SFXN3 | sideroflexin 3 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SKIL | SKI-like proto-oncogene |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SP100 | SP100 nuclear antigen |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TMEM19 | transmembrane protein 19 |
| TMEM63A | transmembrane protein 63A |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRAF3 | TNF receptor-associated factor 3 |
| TROVE2 | TROVE domain family, member 2 |
| VARS | valyl-tRNA synthetase |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB14 | zinc finger and BTB domain containing 14 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZMYND11 | zinc finger, MYND-type containing 11 |
| ZNF696 | zinc finger protein 696 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ACVR2A | activin A receptor, type IIA |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BTBD2 | BTB (POZ) domain containing 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCDC85C | coiled-coil domain containing 85C |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP85 | centrosomal protein 85kDa |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CHKB | choline kinase beta |
| CIC | capicua transcriptional repressor |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CTAGE9 | CTAGE family, member 9 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXO31 | F-box protein 31 |
| FLCN | folliculin |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GLI3 | GLI family zinc finger 3 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HINFP | histone H4 transcription factor |
| ICK | intestinal cell (MAK-like) kinase |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JADE1 | jade family PHD finger 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIFC1 | kinesin family member C1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINS | lines homolog (Drosophila) |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MON1B | MON1 secretory trafficking family member B |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NBAS | neuroblastoma amplified sequence |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCDHB3 | protocadherin beta 3 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PISD | phosphatidylserine decarboxylase |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PRSS22 | protease, serine, 22 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF123 | ring finger protein 123 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RWDD2A | RWD domain containing 2A |
| SAMHD1 | SAM domain and HD domain 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPAG4 | sperm associated antigen 4 |
| STAG3 | stromal antigen 3 |
| TBX19 | T-box 19 |
| THBS3 | thrombospondin 3 |
| TLN1 | talin 1 |
| TLR5 | toll-like receptor 5 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRAIP | TRAF interacting protein |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| USB1 | U6 snRNA biogenesis 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF205 | zinc finger protein 205 |
| ZNF219 | zinc finger protein 219 |
| ZNF276 | zinc finger protein 276 |
| ZNF672 | zinc finger protein 672 |
