substance-related disorders Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
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Genes

23 genes associated with the disease substance-related disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AR androgen receptor
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
COMT catechol-O-methyltransferase
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
ESR1 estrogen receptor 1
FKBP5 FK506 binding protein 5
MAOA monoamine oxidase A
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
PDYN prodynorphin
PENK proenkephalin
PKNOX2 PBX/knotted 1 homeobox 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
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