substantia nigra development Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). (Gene Ontology, GO_0021762)
External Link http://amigo.geneontology.org/amigo/term/GO:0021762
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Genes

45 genes participating in the substantia nigra development biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ATP5PB ATP synthase peripheral stalk-membrane subunit b
ATP5PF ATP synthase peripheral stalk subunit F6
BASP1 brain abundant, membrane attached signal protein 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC14 coiled-coil domain containing 14
CDC42 cell division cycle 42
CKB creatine kinase, brain
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
DYNLL1 dynein, light chain, LC8-type 1
FGF9 fibroblast growth factor 9
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GRID1 glutamate receptor, ionotropic, delta 1
H2BC12L H2B clustered histone 12 like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
INA internexin neuronal intermediate filament protein, alpha
LDHA lactate dehydrogenase A
MAG myelin associated glycoprotein
MAOB monoamine oxidase B
MAPKAP1 mitogen-activated protein kinase associated protein 1
NDRG2 NDRG family member 2
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NPPC natriuretic peptide C
PADI2 peptidyl arginine deiminase, type II
PLP1 proteolipid protein 1
POTEE POTE ankyrin domain family, member E
POTEF POTE ankyrin domain family, member F
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RHOA ras homolog family member A
RRAD Ras-related associated with diabetes
S100A1 S100 calcium binding protein A1
SEC16A SEC16 homolog A (S. cerevisiae)
SIRT2 sirtuin 2
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SYNGR3 synaptogyrin 3
SYPL2 synaptophysin-like 2
TTBK1 tau tubulin kinase 1
UBL4A ubiquitin-like 4A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZNF148 zinc finger protein 148
ZNF430 zinc finger protein 430