succinylsulfathiazole-4265 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the succinylsulfathiazole-4265 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACE angiotensin I converting enzyme
ADGRG1 adhesion G protein-coupled receptor G1
AFF2 AF4/FMR2 family, member 2
AGXT alanine-glyoxylate aminotransferase
ALOX15B arachidonate 15-lipoxygenase, type B
ALPI alkaline phosphatase, intestinal
APOF apolipoprotein F
ARNT aryl hydrocarbon receptor nuclear translocator
ARSD arylsulfatase D
ATXN2L ataxin 2-like
AVPR1A arginine vasopressin receptor 1A
BMP10 bone morphogenetic protein 10
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1QL1 complement component 1, q subcomponent-like 1
CD19 CD19 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CELF2 CUGBP, Elav-like family member 2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CNOT3 CCR4-NOT transcription complex, subunit 3
COL9A3 collagen, type IX, alpha 3
CPN2 carboxypeptidase N, polypeptide 2
CRH corticotropin releasing hormone
CSF1 colony stimulating factor 1 (macrophage)
CST1 cystatin SN
CYSLTR1 cysteinyl leukotriene receptor 1
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DUOX2 dual oxidase 2
DUX4L8 double homeobox 4 like 8
EDN3 endothelin 3
EPHA3 EPH receptor A3
FAM149B1 family with sequence similarity 149, member B1
FAM198B family with sequence similarity 198, member B
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
FLT3LG fms-related tyrosine kinase 3 ligand
FOXL1 forkhead box L1
GAS1 growth arrest-specific 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPC3 glypican 3
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIK3 glutamate receptor, ionotropic, kainate 3
GRM8 glutamate receptor, metabotropic 8
GUCA2A guanylate cyclase activator 2A (guanylin)
HOXD13 homeobox D13
HPGDS hematopoietic prostaglandin D synthase
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGFALS insulin-like growth factor binding protein, acid labile subunit
INS insulin
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KLK13 kallikrein-related peptidase 13
KRT14 keratin 14, type I
KRTAP1-3 keratin associated protein 1-3
KRTAP5-9 keratin associated protein 5-9
LARGE like-glycosyltransferase
LINC00652 long intergenic non-protein coding RNA 652
LRRC75B leucine rich repeat containing 75B
LST1 leukocyte specific transcript 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MNMIP1 manchette microtubule inner protein 1
NEFM neurofilament, medium polypeptide
NF1 neurofibromin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NHLH2 nescient helix loop helix 2
NPR1 natriuretic peptide receptor 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUMA1 nuclear mitotic apparatus protein 1
OR2F2 olfactory receptor, family 2, subfamily F, member 2
OTOF otoferlin
PADI4 peptidyl arginine deiminase, type IV
PIPOX pipecolic acid oxidase
PLVAP plasmalemma vesicle associated protein
PRUNE2 prune homolog 2 (Drosophila)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RIN3 Ras and Rab interactor 3
RS1 retinoschisin 1
SCGB2A1 secretoglobin, family 2A, member 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SH3PXD2A SH3 and PX domains 2A
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC16A6 solute carrier family 16, member 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK5 serine peptidase inhibitor, Kazal type 5
STK3 serine/threonine kinase 3
SYT13 synaptotagmin XIII
TBC1D2 TBC1 domain family, member 2
TBKBP1 TBK1 binding protein 1
TOX3 TOX high mobility group box family member 3
TRGV5 T cell receptor gamma variable 5
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPM3 transient receptor potential cation channel, subfamily M, member 3
UBA7 ubiquitin-like modifier activating enzyme 7
VNN1 vanin 1
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H7B zinc finger CCCH-type containing 7B
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ANOS1 anosmin 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
BBC3 BCL2 binding component 3
BGLAP bone gamma-carboxyglutamate (gla) protein
BNC1 basonuclin 1
C1R complement component 1, r subcomponent
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCP110 centriolar coiled coil protein 110kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CTC1 CTS telomere maintenance complex component 1
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ETNK2 ethanolamine kinase 2
FAM69A family with sequence similarity 69, member A
FAT4 FAT atypical cadherin 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GMEB1 glucocorticoid modulatory element binding protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1E histone cluster 1, H1e
HIST1H4D histone cluster 1, H4d
HIST2H2AA3 histone cluster 2, H2aa3
HOXA1 homeobox A1
IDI2-AS1 IDI2 antisense RNA 1
IPO8 importin 8
KCTD17 potassium channel tetramerization domain containing 17
KIF13A kinesin family member 13A
KLHL25 kelch-like family member 25
LATS1 large tumor suppressor kinase 1
LMO7 LIM domain 7
LOC100286895 cell division cycle 27 homolog pseudogene
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MAPK12 mitogen-activated protein kinase 12
MCC mutated in colorectal cancers
MCTP2 multiple C2 domains, transmembrane 2
MGC12488
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
NPM3 nucleophosmin/nucleoplasmin 3
NRTN neurturin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PARP11 poly (ADP-ribose) polymerase family, member 11
PGPEP1 pyroglutamyl-peptidase I
PIP prolactin-induced protein
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLBD1 phospholipase B domain containing 1
PLCD1 phospholipase C, delta 1
PMCH pro-melanin-concentrating hormone
PODNL1 podocan-like 1
PRF1 perforin 1 (pore forming protein)
PRKG2 protein kinase, cGMP-dependent, type II
PRPH peripherin
QSER1 glutamine and serine rich 1
RAB36 RAB36, member RAS oncogene family
RAI2 retinoic acid induced 2
RNF126P1 ring finger protein 126 pseudogene 1
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
SAMHD1 SAM domain and HD domain 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAYSD1 SAYSVFN motif domain containing 1
SCG5 secretogranin V
SHROOM2 shroom family member 2
SLC12A8 solute carrier family 12, member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYCP2 synaptonemal complex protein 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
THBS3 thrombospondin 3
TM6SF1 transmembrane 6 superfamily member 1
TMEM132A transmembrane protein 132A
TMEM242 transmembrane protein 242
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAC T cell receptor alpha constant
TSPAN8 tetraspanin 8
TWISTNB TWIST neighbor
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VGLL3 vestigial-like family member 3
VN1R1 vomeronasal 1 receptor 1
ZBTB6 zinc finger and BTB domain containing 6
ZFP30 ZFP30 zinc finger protein
ZNF215 zinc finger protein 215
ZNF33B zinc finger protein 33B
ZNF675 zinc finger protein 675
ZNF778 zinc finger protein 778
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZXDC ZXD family zinc finger C