suppressor of fused homolog (Drosophila)|The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 51684)
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17 genes co-occuring with the biological term sufu in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
