sulconazole-3035 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulconazole-3035 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABLIM1 actin binding LIM protein 1
ADAM22 ADAM metallopeptidase domain 22
AKR1C2 aldo-keto reductase family 1, member C2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARMC9 armadillo repeat containing 9
C16ORF45 chromosome 16 open reading frame 45
C19ORF73 chromosome 19 open reading frame 73
C20ORF195 chromosome 20 open reading frame 195
CAV2 caveolin 2
CCDC181 coiled-coil domain containing 181
CCL24 chemokine (C-C motif) ligand 24
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CDHR5 cadherin-related family member 5
CDRT1 CMT1A duplicated region transcript 1
CNTNAP2 contactin associated protein-like 2
COL10A1 collagen, type X, alpha 1
COL18A1 collagen, type XVIII, alpha 1
CTNS cystinosin, lysosomal cystine transporter
CTSF cathepsin F
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAAF1 dynein, axonemal, assembly factor 1
DUSP4 dual specificity phosphatase 4
EDDM3B epididymal protein 3B
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EMC3 ER membrane protein complex subunit 3
EMCN endomucin
ESR1 estrogen receptor 1
FAM127B family with sequence similarity 127, member B
FST follistatin
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GTPBP1 GTP binding protein 1
HABP4 hyaluronan binding protein 4
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
HAP1 huntingtin-associated protein 1
HOXC6 homeobox C6
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFT38 intraflagellar transport 38
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IRF4 interferon regulatory factor 4
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KIF26B kinesin family member 26B
L1CAM L1 cell adhesion molecule
LAMB3 laminin, beta 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC48 leucine rich repeat containing 48
MAN1A2 mannosidase, alpha, class 1A, member 2
MVD mevalonate (diphospho) decarboxylase
MYOD1 myogenic differentiation 1
N4BP3 NEDD4 binding protein 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRL neural retina leucine zipper
NRP1 neuropilin 1
PCDH11Y protocadherin 11 Y-linked
PCP4 Purkinje cell protein 4
PDE4DIP phosphodiesterase 4D interacting protein
PEG3 paternally expressed 3
PLCG1 phospholipase C, gamma 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
RAB25 RAB25, member RAS oncogene family
RAG2 recombination activating gene 2
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBPMS RNA binding protein with multiple splicing
RDH16 retinol dehydrogenase 16 (all-trans)
RGS6 regulator of G-protein signaling 6
RIMS3 regulating synaptic membrane exocytosis 3
RNF122 ring finger protein 122
RPS11 ribosomal protein S11
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERHL2 serine hydrolase-like 2
SH3GL3 SH3-domain GRB2-like 3
SIGLEC9 sialic acid binding Ig-like lectin 9
SIM2 single-minded family bHLH transcription factor 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMTN smoothelin
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSTR4 somatostatin receptor 4
SUSD5 sushi domain containing 5
TAS2R1 taste receptor, type 2, member 1
TBX5 T-box 5
TECPR2 tectonin beta-propeller repeat containing 2
THRB thyroid hormone receptor, beta
TMEM242 transmembrane protein 242
TNN tenascin N
TNP2 transition protein 2 (during histone to protamine replacement)
UBASH3A ubiquitin associated and SH3 domain containing A
ZER1 zyg-11 related, cell cycle regulator
ZFHX3 zinc finger homeobox 3
ZNF177 zinc finger protein 177

decreased expression

Symbol Name
ADM adrenomedullin
AEN apoptosis enhancing nuclease
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APH1B APH1B gamma secretase subunit
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF3 activating transcription factor 3
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCORL1 BCL6 corepressor-like 1
C5AR1 complement component 5a receptor 1
CCL4 chemokine (C-C motif) ligand 4
CD69 CD69 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
DAAM1 dishevelled associated activator of morphogenesis 1
DDIT4 DNA-damage-inducible transcript 4
DENND5B DENN/MADD domain containing 5B
DHRS3 dehydrogenase/reductase (SDR family) member 3
DUSP8 dual specificity phosphatase 8
EDC3 enhancer of mRNA decapping 3
EGLN1 egl-9 family hypoxia-inducible factor 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
FAM172A family with sequence similarity 172, member A
FAM188A family with sequence similarity 188, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLJ21369 uncharacterized protein FLJ21369
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBP2 guanylate binding protein 2, interferon-inducible
HCAR3 hydroxycarboxylic acid receptor 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HOXC8 homeobox C8
IL18 interleukin 18
INHBE inhibin, beta E
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF10 Kruppel-like factor 10
LINC00597 long intergenic non-protein coding RNA 597
LRRC20 leucine rich repeat containing 20
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MPZ myelin protein zero
MYL5 myosin, light chain 5, regulatory
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NACA2 nascent polypeptide-associated complex alpha subunit 2
NARFL nuclear prelamin A recognition factor-like
NINJ2 ninjurin 2
NTSR1 neurotensin receptor 1 (high affinity)
NUPL1 nucleoporin like 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAQR3 progestin and adipoQ receptor family member III
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PLAT plasminogen activator, tissue
PMFBP1 polyamine modulated factor 1 binding protein 1
POLM polymerase (DNA directed), mu
PPARG peroxisome proliferator-activated receptor gamma
PRSS53 protease, serine, 53
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33B RAB33B, member RAS oncogene family
RBM42 RNA binding motif protein 42
RCAN3 RCAN family member 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
SCAI suppressor of cancer cell invasion
SEC31B SEC31 homolog B (S. cerevisiae)
SERTAD3 SERTA domain containing 3
SIK1 salt-inducible kinase 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLFN12 schlafen family member 12
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STBD1 starch binding domain 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEC tec protein tyrosine kinase
TERT telomerase reverse transcriptase
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM104 transmembrane protein 104
TMEM45A transmembrane protein 45A
TRIM36 tripartite motif containing 36
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UCN urocortin
ZNF141 zinc finger protein 141
ZNF215 zinc finger protein 215
ZNF32 zinc finger protein 32
ZNF350 zinc finger protein 350
ZNF480 zinc finger protein 480