sulconazole-3373 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulconazole-3373 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP8L A kinase (PRKA) anchor protein 8-like
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
BDKRB2 bradykinin receptor B2
BIRC3 baculoviral IAP repeat containing 3
C5ORF42 chromosome 5 open reading frame 42
CARD9 caspase recruitment domain family, member 9
CCDC71 coiled-coil domain containing 71
CD52 CD52 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COPA coatomer protein complex, subunit alpha
CPQ carboxypeptidase Q
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DAPK3 death-associated protein kinase 3
DDIT3 DNA-damage-inducible transcript 3
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLX2 distal-less homeobox 2
DMP1 dentin matrix acidic phosphoprotein 1
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EGR2 early growth response 2
ELL2 elongation factor, RNA polymerase II, 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPX eosinophil peroxidase
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
FAM46C family with sequence similarity 46, member C
FGF18 fibroblast growth factor 18
FOS FBJ murine osteosarcoma viral oncogene homolog
GABARAPL1 GABA(A) receptor-associated protein like 1
GALR2 galanin receptor 2
GEM GTP binding protein overexpressed in skeletal muscle
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPR15 G protein-coupled receptor 15
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HIST1H4E histone cluster 1, H4e
HIST1H4H histone cluster 1, H4h
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
JUN jun proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1456 KIAA1456
KIF21B kinesin family member 21B
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL25 kelch-like family member 25
KRT17 keratin 17, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRC17 leucine rich repeat containing 17
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8 mitogen-activated protein kinase 8
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCL1 myeloid cell leukemia 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYOF myoferlin
NOTCH3 notch 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP188 nucleoporin 188kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLXNA2 plexin A2
POU3F4 POU class 3 homeobox 4
PSG4 pregnancy specific beta-1-glycoprotein 4
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RNF17 ring finger protein 17
RPL13P5 ribosomal protein L13 pseudogene 5
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SH3BP2 SH3-domain binding protein 2
SIX3 SIX homeobox 3
SLC35E2 solute carrier family 35, member E2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRCAP Snf2-related CREBBP activator protein
SRSF7 serine/arginine-rich splicing factor 7
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SYCE1L synaptonemal complex central element protein 1-like
TBXA2R thromboxane A2 receptor
TEX14 testis expressed 14
TJAP1 tight junction associated protein 1 (peripheral)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNP2 transition protein 2 (during histone to protamine replacement)
TSC22D3 TSC22 domain family, member 3
WLS wntless Wnt ligand secretion mediator
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFP36 ZFP36 ring finger protein
ZNF407 zinc finger protein 407
ZNF440 zinc finger protein 440
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADRA2C adrenoceptor alpha 2C
AFAP1 actin filament associated protein 1
AKIP1 A kinase (PRKA) interacting protein 1
ALPK1 alpha-kinase 1
ARSB arylsulfatase B
ASB8 ankyrin repeat and SOCS box containing 8
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BGLAP bone gamma-carboxyglutamate (gla) protein
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF27A chromosome 2 open reading frame 27A
C4ORF29 chromosome 4 open reading frame 29
C6ORF47 chromosome 6 open reading frame 47
CALML5 calmodulin-like 5
CCDC132 coiled-coil domain containing 132
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DENND4C DENN/MADD domain containing 4C
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DMC1 DNA meiotic recombinase 1
DPY19L1P1 DPY19L1 pseudogene 1
EGFL7 EGF-like-domain, multiple 7
ETV6 ets variant 6
FAM155B family with sequence similarity 155, member B
FLJ22184
GINS4 GINS complex subunit 4 (Sld5 homolog)
GK3P glycerol kinase 3 pseudogene
GLB1L galactosidase, beta 1-like
GMPR guanosine monophosphate reductase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR143 G protein-coupled receptor 143
GRAMD1C GRAM domain containing 1C
GRTP1 growth hormone regulated TBC protein 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
ICK intestinal cell (MAK-like) kinase
KIAA0754 KIAA0754
KIAA0894 KIAA0894 protein
KIAA1107 KIAA1107
KLC2 kinesin light chain 2
KRT8P12 keratin 8 pseudogene 12
LINC00597 long intergenic non-protein coding RNA 597
LOC100287590 uncharacterized LOC100287590
LRRC37A3 leucine rich repeat containing 37, member A3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MXD3 MAX dimerization protein 3
MYO1D myosin ID
NABP2 nucleic acid binding protein 2
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
NRSN2 neurensin 2
PEX26 peroxisomal biogenesis factor 26
PHACTR4 phosphatase and actin regulator 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLIN3 perilipin 3
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRAMEF11 PRAME family member 11
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFWD3 ring finger and WD repeat domain 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF2 ring finger protein 2
RNF208 ring finger protein 208
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SDC3 syndecan 3
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SNORA21 small nucleolar RNA, H/ACA box 21
SPTBN2 spectrin, beta, non-erythrocytic 2
SRD5A3 steroid 5 alpha-reductase 3
STRN striatin, calmodulin binding protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D19 TBC1 domain family, member 19
TBC1D2 TBC1 domain family, member 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TDRD1 tudor domain containing 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VGF VGF nerve growth factor inducible
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF160 zinc finger protein 160
ZNF286A zinc finger protein 286A
ZNF446 zinc finger protein 446
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF750 zinc finger protein 750