sulfabenzamide-4979 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfabenzamide-4979 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIRE autoimmune regulator
AKT2 v-akt murine thymoma viral oncogene homolog 2
APOC1 apolipoprotein C-I
ARHGAP33 Rho GTPase activating protein 33
ATP11A ATPase, class VI, type 11A
BHMT2 betaine--homocysteine S-methyltransferase 2
BNC2 basonuclin 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CARD14 caspase recruitment domain family, member 14
CCDC85C coiled-coil domain containing 85C
CCL27 chemokine (C-C motif) ligand 27
CCNG2 cyclin G2
CD58 CD58 molecule
CD82 CD82 molecule
CEMP1 cementum protein 1
CFAP69 cilia and flagella associated protein 69
CHAT choline O-acetyltransferase
CLCN7 chloride channel, voltage-sensitive 7
CPA4 carboxypeptidase A4
CYLD cylindromatosis (turban tumor syndrome)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DLX4 distal-less homeobox 4
DOCK6 dedicator of cytokinesis 6
DST dystonin
EFNB3 ephrin-B3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPHA1 EPH receptor A1
EXTL3 exostosin-like glycosyltransferase 3
FANCA Fanconi anemia, complementation group A
GFOD2 glucose-fructose oxidoreductase domain containing 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GLIPR1 GLI pathogenesis-related 1
GPC3 glypican 3
GPER1 G protein-coupled estrogen receptor 1
GPM6B glycoprotein M6B
GPR137 G protein-coupled receptor 137
GSTA4 glutathione S-transferase alpha 4
GYG2 glycogenin 2
HIPK2 homeodomain interacting protein kinase 2
HLF hepatic leukemia factor
INHBA inhibin, beta A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNK10 potassium channel, two pore domain subfamily K, member 10
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLHL22 kelch-like family member 22
LIMS2 LIM and senescent cell antigen-like domains 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MAP2K5 mitogen-activated protein kinase kinase 5
MOB3B MOB kinase activator 3B
MTCP1 mature T-cell proliferation 1
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
MXD4 MAX dimerization protein 4
MYO1F myosin IF
NADK NAD kinase
NCF4 neutrophil cytosolic factor 4, 40kDa
NF2 neurofibromin 2 (merlin)
NR2F1 nuclear receptor subfamily 2, group F, member 1
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PCDHGB5 protocadherin gamma subfamily B, 5
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POFUT1 protein O-fucosyltransferase 1
POPDC3 popeye domain containing 3
POU2F2 POU class 2 homeobox 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRF1 perforin 1 (pore forming protein)
PTCRA pre T-cell antigen receptor alpha
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RND1 Rho family GTPase 1
RPL10L ribosomal protein L10-like
RPLP2 ribosomal protein, large, P2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SETBP1 SET binding protein 1
SGCE sarcoglycan, epsilon
SGK2 serum/glucocorticoid regulated kinase 2
SIDT2 SID1 transmembrane family, member 2
SIX3 SIX homeobox 3
SLC6A16 solute carrier family 6, member 16
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SOX12 SRY (sex determining region Y)-box 12
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAZ tafazzin
THBD thrombomodulin
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM254 transmembrane protein 254
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
UNC93B1 unc-93 homolog B1 (C. elegans)
USP22 ubiquitin specific peptidase 22
WSCD1 WSC domain containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABLIM3 actin binding LIM protein family, member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADSB acyl-CoA dehydrogenase, short/branched chain
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATXN2 ataxin 2
AXIN1 axin 1
C14ORF93 chromosome 14 open reading frame 93
C19ORF73 chromosome 19 open reading frame 73
C2ORF54 chromosome 2 open reading frame 54
CAMTA2 calmodulin binding transcription activator 2
CLDN15 claudin 15
CTAGE9 CTAGE family, member 9
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
EHD3 EH-domain containing 3
ELMO3 engulfment and cell motility 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F2R coagulation factor II (thrombin) receptor
FAM155B family with sequence similarity 155, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HOOK1 hook microtubule-tethering protein 1
HSPA1L heat shock 70kDa protein 1-like
IDI2-AS1 IDI2 antisense RNA 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFNAR1 interferon (alpha, beta and omega) receptor 1
ISG15 ISG15 ubiquitin-like modifier
ITPKB inositol-trisphosphate 3-kinase B
KDM5C lysine (K)-specific demethylase 5C
KIAA0754 KIAA0754
KLHL12 kelch-like family member 12
KREMEN2 kringle containing transmembrane protein 2
LAMA3 laminin, alpha 3
LMBR1L limb development membrane protein 1-like
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC390998 ribosomal protein L10 pseudogene
LRRC8E leucine rich repeat containing 8 family, member E
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MCTP1 multiple C2 domains, transmembrane 1
MFAP2 microfibrillar-associated protein 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOSPD3 motile sperm domain containing 3
MTA2 metastasis associated 1 family, member 2
NPTX1 neuronal pentraxin I
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHEX phosphate regulating endopeptidase homolog, X-linked
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
POM121 POM121 transmembrane nucleoporin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPRS protein tyrosine phosphatase, receptor type, S
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
ROM1 retinal outer segment membrane protein 1
RPGRIP1L RPGRIP1-like
SETD8 SET domain containing (lysine methyltransferase) 8
SHPK sedoheptulokinase
SIRAL2 SIR2 antiphage like 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TET3 tet methylcytosine dioxygenase 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TPK1 thiamin pyrophosphokinase 1
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
USP27X ubiquitin specific peptidase 27, X-linked
WDR91 WD repeat domain 91
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF205 zinc finger protein 205
ZNF329 zinc finger protein 329
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZSCAN31 zinc finger and SCAN domain containing 31