sulfadiazine-1688 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sulfadiazine-1688 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADGRG2 adhesion G protein-coupled receptor G2
ADTRP androgen-dependent TFPI-regulating protein
AK2 adenylate kinase 2
ASB1 ankyrin repeat and SOCS box containing 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BAHCC1 BAH domain and coiled-coil containing 1
BIN1 bridging integrator 1
CAPN9 calpain 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD82 CD82 molecule
CEP162 centrosomal protein 162kDa
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSRP2 cysteine and glycine-rich protein 2
DCAKD dephospho-CoA kinase domain containing
DOCK5 dedicator of cytokinesis 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELOVL5 ELOVL fatty acid elongase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
EVA1B eva-1 homolog B (C. elegans)
FLOT1 flotillin 1
FOXN3 forkhead box N3
FUS FUS RNA binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GOSR2 golgi SNAP receptor complex member 2
GPR137 G protein-coupled receptor 137
GPR27 G protein-coupled receptor 27
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRIK5 glutamate receptor, ionotropic, kainate 5
HAP1 huntingtin-associated protein 1
HDAC11 histone deacetylase 11
HIST1H4H histone cluster 1, H4h
HOXB7 homeobox B7
ING1 inhibitor of growth family, member 1
INPP5J inositol polyphosphate-5-phosphatase J
KDM4C lysine (K)-specific demethylase 4C
KIAA0319L KIAA0319-like
LMAN1 lectin, mannose-binding, 1
MFN1 mitofusin 1
MFSD11 major facilitator superfamily domain containing 11
MYOF myoferlin
N4BP1 NEDD4 binding protein 1
NCALD neurocalcin delta
NFX1 nuclear transcription factor, X-box binding 1
NKTR natural killer cell triggering receptor
NRCAM neuronal cell adhesion molecule
PDCD6 programmed cell death 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PHEX phosphate regulating endopeptidase homolog, X-linked
PIAS1 protein inhibitor of activated STAT, 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLK4 polo-like kinase 4
PLXNB3 plexin B3
PML promyelocytic leukemia
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP5C protein phosphatase 5, catalytic subunit
PTGES prostaglandin E synthase
PVT1 Pvt1 oncogene (non-protein coding)
RANBP3 RAN binding protein 3
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS14 regulator of G-protein signaling 14
RNF126P1 ring finger protein 126 pseudogene 1
RRAGD Ras-related GTP binding D
S100A9 S100 calcium binding protein A9
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMIM14 small integral membrane protein 14
SNX1 sorting nexin 1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPIN1 spindlin 1
STRN striatin, calmodulin binding protein
STX7 syntaxin 7
SYNGR1 synaptogyrin 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLK1 tousled-like kinase 1
TMEM63A transmembrane protein 63A
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TUBGCP3 tubulin, gamma complex associated protein 3
UBXN6 UBX domain protein 6
UTRN utrophin
VASH2 vasohibin 2
WDR78 WD repeat domain 78
YY2 YY2 transcription factor
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF286A zinc finger protein 286A
ZNF350 zinc finger protein 350
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADCY6 adenylate cyclase 6
AES amino-terminal enhancer of split
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANXA2P3 annexin A2 pseudogene 3
APOD apolipoprotein D
ARMC6 armadillo repeat containing 6
ARRB2 arrestin, beta 2
ATXN2 ataxin 2
BCL9 B-cell CLL/lymphoma 9
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CAPN1 calpain 1, (mu/I) large subunit
CAPN15 calpain 15
CCDC9 coiled-coil domain containing 9
CCNE1 cyclin E1
CCNO cyclin O
CHKB choline kinase beta
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CTSV cathepsin V
CYFIP2 cytoplasmic FMR1 interacting protein 2
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DUSP8 dual specificity phosphatase 8
EFHD2 EF-hand domain family, member D2
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
FANCC Fanconi anemia, complementation group C
FLJ22184
GALK1 galactokinase 1
GALT galactose-1-phosphate uridylyltransferase
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLI3 GLI family zinc finger 3
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GSTA4 glutathione S-transferase alpha 4
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMHA1 histocompatibility (minor) HA-1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL17RA interleukin 17 receptor A
KDM5C lysine (K)-specific demethylase 5C
LAMB3 laminin, beta 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MPI mannose phosphate isomerase
MTERF1 mitochondrial transcription termination factor 1
MXD3 MAX dimerization protein 3
MYH9 myosin, heavy chain 9, non-muscle
NPIPB15 nuclear pore complex interacting protein family, member B15
NPY1R neuropeptide Y receptor Y1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRSN2 neurensin 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OCEL1 occludin/ELL domain containing 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PGP phosphoglycolate phosphatase
PLA2G15 phospholipase A2, group XV
PLEKHA6 pleckstrin homology domain containing, family A member 6
PODXL2 podocalyxin-like 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PSKH1 protein serine kinase H1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM38 RNA binding motif protein 38
S100A4 S100 calcium binding protein A4
SCAMP5 secretory carrier membrane protein 5
SH2D4A SH2 domain containing 4A
SIRT6 sirtuin 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAP29 synaptosomal-associated protein, 29kDa
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STX5 syntaxin 5
TET3 tet methylcytosine dioxygenase 3
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TKFC triokinase/FMN cyclase
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM5 tripartite motif containing 5
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
USP20 ubiquitin specific peptidase 20
XAB2 XPA binding protein 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YEATS2 YEATS domain containing 2
ZMAT5 zinc finger, matrin-type 5
ZNF205 zinc finger protein 205
ZNF408 zinc finger protein 408
ZNF573 zinc finger protein 573
ZNF574 zinc finger protein 574
ZNF768 zinc finger protein 768
ZNF8 zinc finger protein 8