sulfadiazine-1810 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfadiazine-1810 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKTIP AKT interacting protein
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARHGAP10 Rho GTPase activating protein 10
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ARTN artemin
ASPH aspartate beta-hydroxylase
ATM ATM serine/threonine kinase
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAX BCL2-associated X protein
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C2ORF68 chromosome 2 open reading frame 68
C6ORF62 chromosome 6 open reading frame 62
CCDC88A coiled-coil domain containing 88A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLDN8 claudin 8
DBF4B DBF4 zinc finger B
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DZIP3 DAZ interacting zinc finger protein 3
ELF2 E74-like factor 2 (ets domain transcription factor)
ERLIN1 ER lipid raft associated 1
FBN1 fibrillin 1
FCF1 FCF1 rRNA-processing protein
FHL1 four and a half LIM domains 1
FOXN3 forkhead box N3
FOXO1 forkhead box O1
FSCN1 fascin actin-bundling protein 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GJC1 gap junction protein, gamma 1, 45kDa
GM2A GM2 ganglioside activator
GOLGA8B golgin A8 family, member B
GPR3 G protein-coupled receptor 3
GSR glutathione reductase
GUSBP3 glucuronidase, beta pseudogene 3
HDGFRP3 hepatoma-derived growth factor, related protein 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HNMT histamine N-methyltransferase
HOXD1 homeobox D1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INO80B INO80 complex subunit B
JAK2 Janus kinase 2
KRIT1 KRIT1, ankyrin repeat containing
KRT33A keratin 33A, type I
LMAN1 lectin, mannose-binding, 1
LPAR6 lysophosphatidic acid receptor 6
LYPD3 LY6/PLAUR domain containing 3
LYST lysosomal trafficking regulator
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAT2A methionine adenosyltransferase II, alpha
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
MCM4 minichromosome maintenance complex component 4
MED14 mediator complex subunit 14
MED16 mediator complex subunit 16
MET MET proto-oncogene, receptor tyrosine kinase
MPDZ multiple PDZ domain protein
MVK mevalonate kinase
N4BP2L2 NEDD4 binding protein 2-like 2
NIPAL3 NIPA-like domain containing 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PASK PAS domain containing serine/threonine kinase
PCDH1 protocadherin 1
PCLO piccolo presynaptic cytomatrix protein
PDE4DIP phosphodiesterase 4D interacting protein
PECAM1 platelet/endothelial cell adhesion molecule 1
PEX1 peroxisomal biogenesis factor 1
PICALM phosphatidylinositol binding clathrin assembly protein
PLEKHO1 pleckstrin homology domain containing, family O member 1
PTBP3 polypyrimidine tract binding protein 3
PTGES prostaglandin E synthase
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RDX radixin
RNF216 ring finger protein 216
RPL10 ribosomal protein L10
RRM1 ribonucleotide reductase M1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC39A9 solute carrier family 39, member 9
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SOS2 son of sevenless homolog 2 (Drosophila)
SS18 synovial sarcoma translocation, chromosome 18
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCF3 transcription factor 3
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TRIM25 tripartite motif containing 25
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
TUBGCP3 tubulin, gamma complex associated protein 3
TWF1 twinfilin actin binding protein 1
UBOX5 U-box domain containing 5
USP24 ubiquitin specific peptidase 24
VEGFA vascular endothelial growth factor A
WHSC1 Wolf-Hirschhorn syndrome candidate 1

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADGRF1 adhesion G protein-coupled receptor F1
ALG12 ALG12, alpha-1,6-mannosyltransferase
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
C16ORF62 chromosome 16 open reading frame 62
C6ORF47 chromosome 6 open reading frame 47
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CCDC25 coiled-coil domain containing 25
CCDC85C coiled-coil domain containing 85C
CEP170B centrosomal protein 170B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLCN2 chloride channel, voltage-sensitive 2
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COQ4 coenzyme Q4
CTNNBL1 catenin, beta like 1
CTSF cathepsin F
CTSK cathepsin K
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCLRE1A DNA cross-link repair 1A
DCLRE1B DNA cross-link repair 1B
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
ERCC8 excision repair cross-complementation group 8
ETV4 ets variant 4
FAM53B family with sequence similarity 53, member B
FLJ22184
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR1 G protein-coupled receptor 1
HDAC3 histone deacetylase 3
HDAC5 histone deacetylase 5
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HPS6 Hermansky-Pudlak syndrome 6
IFI6 interferon, alpha-inducible protein 6
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ISL1 ISL LIM homeobox 1
KIAA0922 KIAA0922
KIF16B kinesin family member 16B
KIFC3 kinesin family member C3
LIMS2 LIM and senescent cell antigen-like domains 2
MAGEA3 melanoma antigen family A3
MAST3 microtubule associated serine/threonine kinase 3
MCMBP minichromosome maintenance complex binding protein
MNX1 motor neuron and pancreas homeobox 1
MOB3B MOB kinase activator 3B
MOGS mannosyl-oligosaccharide glucosidase
MRPL52 mitochondrial ribosomal protein L52
MT1HL1 metallothionein 1H-like 1
MYO1D myosin ID
NDRG4 NDRG family member 4
NRTN neurturin
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLSCR4 phospholipid scramblase 4
POLH polymerase (DNA directed), eta
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTTG3P pituitary tumor-transforming 3, pseudogene
RNF121 ring finger protein 121
RNF31 ring finger protein 31
ROGDI rogdi homolog (Drosophila)
RPAP1 RNA polymerase II associated protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMD9 sterile alpha motif domain containing 9
SCARA3 scavenger receptor class A, member 3
SCML2 sex comb on midleg-like 2 (Drosophila)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1B SET domain containing 1B
SHROOM2 shroom family member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SPATA2L spermatogenesis associated 2-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAC SH3 and cysteine rich domain
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYT17 synaptotagmin XVII
TGFB3 transforming growth factor, beta 3
TMEM8A transmembrane protein 8A
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNNI3 troponin I type 3 (cardiac)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VWA1 von Willebrand factor A domain containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC10 zinc finger, CCHC domain containing 10
ZMAT5 zinc finger, matrin-type 5
ZNF324 zinc finger protein 324
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747
ZNF8 zinc finger protein 8
ZSCAN16 zinc finger and SCAN domain containing 16